A Small Molecule Activator of p300/CBP Histone Acetyltransferase Promotes Survival and Neurite Growth in a Cellular Model of Parkinson’s Disease

Region-specific role of growth differentiation factor-5 in the establishment of sympathetic innervation

(2016) Gerard W. O’Keeffe et al.   Neural Development

Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial

(2015) C. Warren Olanow et al.   ANNALS OF NEUROLOGY

The proinflammatory cytokine, interleukin-17A, augments mitochondrial function and neurite outgrowth of cultured adult sensory neurons derived from normal and diabetic rats

(2015) Tarek Habash et al.   EXPERIMENTAL NEUROLOGY

Crafting the Brain – Role of Histone Acetyltransferases in Neural Development and Disease

(2014) Bilal N. Sheikh   CELL AND TISSUE RESEARCH

Class-IIa Histone Deacetylase Inhibition Promotes the Growth of Neural Processes and Protects Them Against Neurotoxic Insult

(2014) Louise M. Collins et al.   MOLECULAR NEUROBIOLOGY

Neurotrophic factors: from neurodevelopmental regulators to novel therapies for Parkinson′s disease

(2014) GerardW O′Keeffe et al.   Neural Regeneration Research

Canonical BMP–Smad Signalling Promotes Neurite Growth in Rat Midbrain Dopaminergic Neurons

(2014) Shane V. Hegarty et al.   NEUROMOLECULAR MEDICINE

Histone Decacetylase Inhibitors Prevent Mitochondrial Fragmentation and Elicit Early Neuroprotection against MPP+

(2013) Min Zhu et al.   CNS Neuroscience & Therapeutics

Lysine Acetyltransferases CBP and p300 as Therapeutic Targets in Cognitive and Neurodegenerative Disorders

(2013) Luis Valor et al.   CURRENT PHARMACEUTICAL DESIGN

CBP regulates the differentiation of interneurons from ventral forebrain neural precursors during murine development

(2013) David Tsui et al.   DEVELOPMENTAL BIOLOGY

AMP-activated protein kinase mediates activity-dependent axon branching by recruiting mitochondria to axon

(2013) Kentaro Tao et al.   Developmental Neurobiology

Chromatin structure, pluripotency and differentiation

(2013) Lourdes Serrano et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

A Novel Activator of CBP/p300 Acetyltransferases Promotes Neurogenesis and Extends Memory Duration in Adult Mice

(2013) S. Chatterjee et al.   JOURNAL OF NEUROSCIENCE

Charge density distribution and the electrostatic moments of CTPB in the active site of p300 enzyme: A DFT and charge density study

(2013) B. Devipriya et al.   JOURNAL OF THEORETICAL BIOLOGY

BMP2 and GDF5 induce neuronal differentiation through a Smad dependant pathway in a model of human midbrain dopaminergic neurons

(2013) Shane V. Hegarty et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The coming crisis: Obtaining care for the growing burden of neurodegenerative conditions

(2013) E. R. Dorsey et al.   NEUROLOGY

Sodium butyrate improves locomotor impairment and early mortality in a rotenone-induced Drosophila model of Parkinson’s disease

(2013) R. St. Laurent et al.   NEUROSCIENCE

Acetyltransferases (HATs) as Targets for Neurological Therapeutics

(2013) Anne Schneider et al.   Neurotherapeutics

Epigenetic targeting of histone deacetylase: Therapeutic potential in Parkinson's disease?

(2013) Ian F. Harrison et al.   PHARMACOLOGY & THERAPEUTICS

Krüppel-like Factor 11 Differentially Couples to Histone Acetyltransferase and Histone Methyltransferase Chromatin Remodeling Pathways to Transcriptionally Regulate Dopamine D2 Receptor in Neuronal Cells

(2012) Seungmae Seo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The histone acetyltransferase p300 promotes intrinsic axonal regeneration

(2011) Perrine Gaub et al.   BRAIN

Exposure of foetal neural progenitor cells to IL-1β impairs their proliferation and alters their differentiation - a role for maternal inflammation?

(2011) Sean J. Crampton et al.   JOURNAL OF NEUROCHEMISTRY

 -Synuclein Negatively Regulates Protein Kinase C  Expression to Suppress Apoptosis in Dopaminergic Neurons by Reducing p300 Histone Acetyltransferase Activity

(2011) H. Jin et al.   JOURNAL OF NEUROSCIENCE

Neuropathology of sporadic Parkinson's disease: Evaluation and changes of concepts

(2011) Kurt A. Jellinger   MOVEMENT DISORDERS

Protective effects of valproic acid on the nigrostriatal dopamine system in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

(2011) S.K. Kidd et al.   NEUROSCIENCE

Neurotrophic Effects of Growth/Differentiation Factor 5 in a Neuronal Cell Line

(2011) André Toulouse et al.   NEUROTOXICITY RESEARCH

Serotonin and dopamine striatal innervation in Parkinson’s disease and Huntington’s chorea

(2011) Catherine Bédard et al.   PARKINSONISM & RELATED DISORDERS

Dynamic association of p300 with the promoter of the G protein-coupled rat delta opioid receptor gene during NGF-induced neuronal differentiation

(2010) Yulong L. Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibition

(2010) Sarah K. Kidd et al.   BRAIN RESEARCH

HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300 and P/CAF-dependent p53 acetylation

(2010) P Gaub et al.   CELL DEATH AND DIFFERENTIATION

New Anacardic Acid-Inspired Benzamides: Histone Lysine Acetyltransferase Activators

(2010) José A. Souto et al.   ChemMedChem

CBP Histone Acetyltransferase Activity Regulates Embryonic Neural Differentiation in the Normal and Rubinstein-Taybi Syndrome Brain

(2010) Jing Wang et al.   DEVELOPMENTAL CELL

Extracellular signals regulating sympathetic neuron survival and target innervation during development

(2009) Alun M. Davies   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Parkinson's disease

(2009) Andrew J Lees et al.   LANCET

Retinoid Signaling and Neurogenin2 Function Are Coupled for the Specification of Spinal Motor Neurons through a Chromatin Modifier CBP

(2009) Seunghee Lee et al.   NEURON

Multiple roles of HDAC inhibition in neurodegenerative conditions

(2009) De-Maw Chuang et al.   TRENDS IN NEUROSCIENCES

Synthesis of Benzamides Related to Anacardic Acid and Their Histone Acetyltransferase (HAT) Inhibitory Activities

(2008) José A. Souto et al.   ChemMedChem

Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders

(2008) T ABEL et al.   CURRENT OPINION IN PHARMACOLOGY

Histone deacetylase inhibitors: possible implications for neurodegenerative disorders

(2008) Eric Hahnen et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons

(2008) Xuefei Wu et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Parkinson's disease: clinical features and diagnosis

(2008) J Jankovic   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Nuclear Factor  B Signaling Either Stimulates or Inhibits Neurite Growth Depending on the Phosphorylation Status of p65/RelA

(2008) H. Gutierrez et al.   JOURNAL OF NEUROSCIENCE

Epigenetics in the Nervous System

(2008) Y. Jiang et al.   JOURNAL OF NEUROSCIENCE

Intrinsically Fluorescent Carbon Nanospheres as a Nuclear Targeting Vector: Delivery of Membrane-Impermeable Molecule to Modulate Gene Expression In Vivo

(2008) B. Ruthrotha Selvi et al.   NANO LETTERS

Therapeutic application of histone deacetylase inhibitors for central nervous system disorders

(2008) Aleksey G. Kazantsev et al.   NATURE REVIEWS DRUG DISCOVERY