Neuroprotective Effect of the Novel Compound ITH33/IQM9.21 Against Oxidative Stress and Na+ and Ca2+ Overload in Motor Neuron-like NSC-34 Cells

The Neuroprotective Drug Riluzole Acts via Small Conductance Ca2+-Activated K+ Channels to Ameliorate Defects in Spinal Muscular Atrophy Models

(2013) M. Dimitriadi et al.   JOURNAL OF NEUROSCIENCE

Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia

(2012) Silvia Lorrio et al.   NEUROPHARMACOLOGY

Multi-target novel neuroprotective compound ITH33/IQM9.21 inhibits calcium entry, calcium signals and exocytosis

(2011) Marcos Maroto et al.   CELL CALCIUM

Quantification and identification of mitochondrial proteins containing vicinal dithiols

(2010) Raquel Requejo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A Review of the Neural Mechanisms of Action and Clinical Efficiency of Riluzole in Treating Amyotrophic Lateral Sclerosis: What have we Learned in the Last Decade?

(2010) Mark C. Bellingham   CNS Neuroscience & Therapeutics

Mitochondrial dysfunction and intracellular calcium dysregulation in ALS

(2010) Hibiki Kawamata et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Neuroprotective and Cholinergic Properties of Multifunctional Glutamic Acid Derivatives for the Treatment of Alzheimer’s Disease

(2009) Mariana P. Arce et al.   JOURNAL OF MEDICINAL CHEMISTRY

Amyotrophic lateral sclerosis

(2009) Lokesh C Wijesekera et al.   Orphanet Journal of Rare Diseases

Calcium signaling and neurodegenerative diseases

(2009) Ilya Bezprozvanny   TRENDS IN MOLECULAR MEDICINE

Riluzole blocks persistent Na+and Ca2+currents and modulates release of glutamate via presynaptic NMDA receptors on neonatal rat hypoglossal motoneuronsin vitro

(2008) Nerijus Lamanauskas et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Riluzole-induced block of voltage-gated Na+ current and activation of BKCa channels in cultured differentiated human skeletal muscle cells

(2007) Ya-Jean Wang et al.   LIFE SCIENCES