Aberrant CpG Methylation Mediates Abnormal Transcription of MAO-A Induced by Acute and Chronic l-3,4-Dihydroxyphenylalanine Administration in SH-SY5Y Neuronal Cells

Monoamine oxidase a gene promoter methylation and transcriptional downregulation in an offender population with antisocial personality disorder

(2015) D. Checknita et al.   BRITISH JOURNAL OF PSYCHIATRY

Modulation of monoamine oxidase (MAO) expression in neuropsychiatric disorders: genetic and environmental factors involved in type A MAO expression

(2015) Makoto Naoi et al.   JOURNAL OF NEURAL TRANSMISSION

Molecular mechanism of monoamine oxidase A gene regulation under inflammation and ischemia-like conditions: key roles of the transcription factors GATA2, Sp1 and TBP

(2015) Vinayak Gupta et al.   JOURNAL OF NEUROCHEMISTRY

Amelioration of l-Dopa-Associated Dyskinesias with Triterpenoic Acid in a Parkinsonian Rat Model

(2015) Babongile C. Ndlovu et al.   NEUROTOXICITY RESEARCH

Pharmacoepigenetics of depression: no major influence of MAO-A DNA methylation on treatment response

(2014) Katharina Domschke et al.   JOURNAL OF NEURAL TRANSMISSION

TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells

(2014) C. Jin et al.   NUCLEIC ACIDS RESEARCH

L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum

(2014) Gregory Porras et al.   Scientific Reports

Presynaptic Mechanisms of l-DOPA-Induced Dyskinesia: The Findings, the Debate, and the Therapeutic Implications

(2014) M. Angela Cenci   Frontiers in Neurology

A DNA Methyltransferase Inhibitor, 5-Aza-2′-Deoxycytidine, Exacerbates Neurotoxicity and Upregulates Parkinson's Disease-Related Genes in Dopaminergic Neurons

(2013) Yong Wang et al.   CNS Neuroscience & Therapeutics

Dual Inhibitors of Monoamine Oxidase and Cholinesterase for the Treatment of Alzheimer Disease

(2013) Matilde Yanez et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction

(2013) Andrii Rudenko et al.   NEURON

Epigenetic Landscape of Parkinson’s Disease: Emerging Role in Disease Mechanisms and Therapeutic Modalities

(2013) Navneet Ammal Kaidery et al.   Neurotherapeutics

Evidence that the methylation state of the monoamine oxidase A (MAOA) gene predicts brain activity of MAO A enzyme in healthy men

(2012) Elena Shumay et al.   Epigenetics

Rasagiline and selegiline, inhibitors of type B monoamine oxidase, induce type A monoamine oxidase in human SH-SY5Y cells

(2012) Keiko Inaba-Hasegawa et al.   JOURNAL OF NEURAL TRANSMISSION

Acute Administration of L-Dopa Induces Changes in Methylation Metabolites, Reduced Protein Phosphatase 2A Methylation, and Hyperphosphorylation of Tau Protein in Mouse Brain

(2012) T. Bottiglieri et al.   JOURNAL OF NEUROSCIENCE

Oxidative stress induces DNA demethylation and histone acetylation in SH-SY5Y cells: potential epigenetic mechanisms in gene transcription in Aβ production

(2012) Xinling Gu et al.   NEUROBIOLOGY OF AGING

l-DOPA pharmacokinetics in the MPTP-lesioned macaque model of Parkinson's disease

(2012) Philippe Huot et al.   NEUROPHARMACOLOGY

Altered cerebellar organization and function in monoamine oxidase A hypomorphic mice

(2012) Loai Alzghoul et al.   NEUROPHARMACOLOGY

The role of GRK6 in animal models of Parkinson's Disease and L-DOPA treatment

(2012) Francesca Managò et al.   Scientific Reports

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

(2011) Junjie U. Guo et al.   CELL

DNA Demethylation Dynamics

(2011) Nidhi Bhutani et al.   CELL

Transcriptional regulation and multiple functions of MAO genes

(2011) Jean C. Shih et al.   JOURNAL OF NEURAL TRANSMISSION

Crossover comparison of IPX066 and a standard levodopa formulation in advanced Parkinson's disease

(2011) Robert A. Hauser et al.   MOVEMENT DISORDERS

Contribution of pre-synaptic mechanisms to l-DOPA-induced dyskinesia

(2011) M. Carta et al.   NEUROSCIENCE

Efficacy, safety, and patient preference of monoamine oxidase B inhibitors in the treatment of Parkinson's disease

(2011) Bradley Robottom   Patient Preference and Adherence

Levodopa Deactivates Enzymes That Regulate Thiol−Disulfide Homeostasis and Promotes Neuronal Cell Death: Implications for Therapy of Parkinson’s Disease

(2010) Elizabeth A. Sabens et al.   BIOCHEMISTRY

L-Dopa therapy increases homocysteine concentration in cerebrospinal fluid from patients with Parkinson’s disease

(2010) Chiaki Isobe et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Levodopa-induced dyskinesias in patients with Parkinson's disease: filling the bench-to-bedside gap

(2010) Paolo Calabresi et al.   LANCET NEUROLOGY

Levodopa: the story so far

(2010) Alison Abbott   NATURE

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

(2010) Shinsuke Ito et al.   NATURE

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Molecular mechanisms of L-DOPA-induced dyskinesia

(2008) Peter Jenner   NATURE REVIEWS NEUROSCIENCE

Oxidative and Inflammatory Pathways in Parkinson’s Disease

(2008) Rebecca L. Miller et al.   NEUROCHEMICAL RESEARCH