Article
Clinical Neurology
Caiqiang Xue, Bin Zhang, Juan Deng, Xianwang Liu, Shenglin Li, Junlin Zhou
Summary: This study used diffusion-weighted imaging (DWI) to distinguish giant cell glioblastoma (GC) from classic glioblastoma (GBM), showing that the ADC(min) parameter can improve the accuracy of preoperative differential diagnosis of the two tumor types.
WORLD NEUROSURGERY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Felipe S. Furtado, Nathaniel D. Mercaldo, Thomas Vahle, Thomas Benkert, William R. Bradley, Lisa Ratanaprasatporn, Ravi Teja Seethamraju, Mukesh G. Harisinghani, Susanna Lee, Krista Suarez-Weiss, Lale Umutlu, Ciprian Catana, Kelsey L. Pomykala, Liran Domachevsky, Hanna Bernstine, David Groshar, Bruse R. Rosen, Onofrio Antonio Catalano
Summary: This study compared standard (STD-DWI) single-shot echo-planar imaging DWI and simultaneous multislice (SMS) DWI during whole-body positron emission tomography (PET)/MRI in terms of acquisition time, image quality, and lesion detection. The results showed that SMS-DWI shortened the acquisition time and maintained or improved the diagnostic yield in most anatomical regions. Therefore, SMS-DWI has important clinical application prospects in cancer staging and restaging.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Konrad A. Kruk, Tobias J. Dietrich, Simon Wildermuth, Sebastian Leschka, Andreas Toepfer, Stephan Waelti, Chan-Hi Olaf Kim, Sabine Guesewell, Tim Fischer
Summary: This study evaluated the feasibility of diffusion-weighted imaging (DWI) in diagnosing osteomyelitis and bone marrow edema in the forefoot. The measurement of apparent diffusion coefficient (ADC) values allowed for differentiation between healthy and abnormal bone and provided specific cutoff values for the confirmation or exclusion of osteomyelitis.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Qingqing Yan, Fuyan Li, Yi Cui, Yong Wang, Xiao Wang, Wenjing Jia, Xinhui Liu, Yuting Li, Huan Chang, Feng Shi, Yuwei Xia, Qing Zhou, Qingshi Zeng
Summary: This study aimed to develop and validate a deep learning model using conventional MRI and DWI to differentiate glioblastoma from single brain metastasis. The single-MRI-sequence DL models, including the T model and T&P model, achieved high AUC values in the validation set. The combination model showed improved classification performance when DWI was combined with T2WI and contrast-enhanced T1WI.
JOURNAL OF DIGITAL IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yang Guo, Zeyu Ma, Dongling Pei, Wenchao Duan, Yu Guo, Zhongyi Liu, Fangzhan Guan, Zilong Wang, Aoqi Xing, Zhixuan Guo, Lin Luo, Weiwei Wang, Bin Yu, Jinqiao Zhou, Yuchen Ji, Dongming Yan, Jingliang Cheng, Xianzhi Liu, Jing Yan, Zhenyu Zhang
Summary: By analyzing radiomic features from diffusion-weighted imaging (DWI), a three-class radiomic model can be trained to classify three molecular subtypes (IDHmut-noncodel, IDHwt, and IDHmut-codel) of adult gliomas, providing an alternative method for patients who don't have access to genetic testing.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Review
Oncology
Andrea Romano, Serena Palizzi, Allegra Romano, Giulia Moltoni, Alberto Di Napoli, Francesca Maccioni, Alessandro Bozzao
Summary: Differential diagnosis, therapy response assessment, correlation between imaging and prognosis, and biomolecular findings remain challenges in neuro-oncology imaging. Though sophisticated MRI sequences and artificial intelligence are researched, Diffusion Weighted Imaging (DWI) is a commonly used and effective tool that provides information on tumor grading, differential diagnosis, molecular profile, and therapy response. DWI offers functional and physiological information regarding brain neoplasia in addition to its clinical purpose. A literature review identified 179 articles on the potential role of DWI in neuro-oncology.
Review
Clinical Neurology
Sacha Posener, Ghazi Hmeydia, Joseph Benzakoun, Catherine Oppenheim, Jean-Claude Baron, Guillaume Turc
Summary: This systematic review and meta-analysis examined the prevalence, associated factors, and presumed causes of remote diffusion-weighted imaging lesions (RDWILs) in patients with spontaneous intracerebral hemorrhage (ICH). The results showed that RDWILs were detected in approximately 25% of acute ICH patients and were associated with neuroimaging features of microangiopathy, atrial fibrillation, clinical severity, elevated blood pressure, ICH volume, and the presence of subarachnoid or intraventricular hemorrhage. RDWILs were also associated with poor functional outcome at 3 months. Further studies are needed to investigate the impact of specific ICH treatment strategies on reducing RDWILs and improving outcomes.
Review
Medicine, General & Internal
Tzu-Hsin Huang, Ming-Chi Lai, Yu-Shiue Chen, Chin-Wei Huang
Summary: This review focuses on the fundamentals of DWI and its associated techniques, such as apparent diffusion coefficient, diffusion tensor imaging, and tractography, as well as their impact on epilepsy in terms of differential diagnosis, epileptic foci determination, and prognosis prediction.
Article
Oncology
Torgeir Mo, Siri Helene Bertelsen Brandal, Alvaro Kohn-Luque, Olav Engebraaten, Vessela N. Kristensen, Thomas Fleischer, Tord Hompland, Therese Seierstad
Summary: Hypoxia is common in solid tumors and is associated with treatment resistance. Identifying hypoxia in solid tumors is important for treatment planning. This study validates the concept of hypoxia in breast cancer and develops a new approach for hypoxia imaging.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ho Young Park, Chong Hyun Suh, Woo Hyun Shim, Seon-Ok Kim, Woo Seok Kim, Sohee Jeong, Jae-Hong Lee, Sang Joon Kim
Summary: The study identified age and diffusion restriction in the caudate nucleus and putamen as independent prognostic factors for poor overall survival in patients with sporadic Creutzfeldt-Jakob disease. The DWI prognostic score model based on these features may be useful for disease stratification in clinical settings, with excellent interobserver agreement.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Davide Maraghelli, Michele Pietragalla, Cesare Cordopatri, Cosimo Nardi, Anna Julie Peired, Giandomenico Maggiore, Stefano Colagrande
Summary: Salivary gland tumours, rare and mainly located in the parotid gland, vary in malignancy based on location. Fine needle aspiration cytology and core needle biopsy are key for diagnosis, while MRI plays a growing role in providing additional information for assessment.
EUROPEAN JOURNAL OF RADIOLOGY
(2021)
Article
Oncology
Philipp Mayer, Anne Kraft, Wilfried Roth, Thilo Hackert, Frank Bergmann, Hans-Ulrich Kauczor, Verena Steinle, Ekaterina Khristenko, Miriam Klauss, Matthias M. Gaida
Summary: This study evaluated the potential of DW-MRI as an imaging biomarker for EMT in PDAC, finding significant correlations between ADC values and expression profiles of E-cadherin, Runx2, and Zeb1. Tumors with higher ADC values showed higher E-cadherin expression and lower Runx2 and Zeb1 expression, indicating a potential role for personalized EMT-targeted therapies based on DW-MRI findings in PDAC patients.
Article
Medicine, General & Internal
Letizia Macconi, Valeria Galici, Marco Di Maurizio, Enrica Rossi, Giovanni Taccetti, Vito Terlizzi
Summary: This observational study examined the changes in chest MRI of three CF adult patients three months after starting elexacaftor/tezacaftor and ivacaftor therapy. The results showed a significant reduction in mucus plugging and bronchial wall thickening, as well as an improvement in diffusion-weighted MRI score. Spirometric parameters, nutritional status, and sweat chloride also improved. These preliminary findings suggest that chest MRI could be a valuable tool for assessing disease progression in CF patients receiving modulatory drug therapy.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Silvana Sarria-Estrada, Estevo Santamarina, Manuel Quintana, Deborah Pareto, Maria Sueiras, Cristina Auger, Manuel Toledo, Alex Rovira
Summary: This study analyzed MRI features in patients with status epilepticus (SE), finding abnormalities in over half of the patients. Longer SE duration and the presence of lateralized periodic discharges (LPDs) on EEG were associated with SE-related MRI abnormalities and the development of mesial temporal sclerosis (MTS).
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shivani Ahlawat, Julie Paik, Filippo Del Grande, Elias S. Paris, Parvinder Sujlana, Laura M. Fayad
Summary: In patients with fibrosing systemic sclerosis-associated myopathy, intramuscular and fascial edema are more common on MRI, while patients with non-fibrosing myopathy often exhibit fatty replacement and atrophy.
