Synthetic modified pyrrolo[1,4] benzodiazepine molecules demonstrate selective anticancer activity by targeting the human ligase 1 enzyme: An in silico and in vitro mechanistic study

Title
Synthetic modified pyrrolo[1,4] benzodiazepine molecules demonstrate selective anticancer activity by targeting the human ligase 1 enzyme: An in silico and in vitro mechanistic study
Authors
Keywords
Ligase inhibitor, DNA ligase 1, Replication, Colon cancer, Hepatic cancer, Apoptosis, PBD derivatives
Journal
CHEMICO-BIOLOGICAL INTERACTIONS
Volume 237, Issue -, Pages 115-124
Publisher
Elsevier BV
Online
2015-06-14
DOI
10.1016/j.cbi.2015.05.024

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