Article
Medicine, General & Internal
Jean Rama Surya, Barshen Habelhah, Jonathan Haroon, Kennedy Mahdavi, Kaya Jordan, Sergio Becerra, Victoria Venkatraman, Chloe Deveney, Alexander Bystritsky, Taylor Kuhn, Sheldon Jordan
Summary: The present study investigates a potential method of optimizing effective strategies for the functional lateralization of the dorsolateral prefrontal cortex (dlPFC) while in a scanner. The results demonstrated that 21.4% of right-handed individuals showed a dominant dlPFC localized to the right hemisphere rather than the assumed left, and 16.7% of left-handers were dominant in their left hemisphere. The task completed in the scanner might be an efficient method for localizing a potential dlPFC target for the purpose of brain stimulation (e.g., TMS), though further study replications are needed to extend and validate these findings.
Article
Neurosciences
Shintaro Uehara, Firas Mawase, Kendra M. Cherry-Allen, Keith Runnalls, Maheen Khan, Pablo Celnik
Summary: This study investigated the neurophysiological effects of tDCS over the right lateral PFC on PFC-M1 IHI. The results showed that tDCS did not modulate the magnitude of PFC-M1 IHI, but connectivity changed during motor tasks with Go/NoGo decisions.
Review
Neurosciences
Fiorenzo Moscatelli, Antonietta Messina, Anna Valenzano, Vincenzo Monda, Monica Salerno, Francesco Sessa, Ester La Torre, Domenico Tafuri, Alessia Scarinci, Michela Perrella, Gabriella Marsala, Marcellino Monda, Giuseppe Cibelli, Chiara Porro, Giovanni Messina
Summary: Transcranial magnetic stimulation, introduced in 1985, has provided important innovations in the study of cortical excitability, allowing for in-depth exploration of motor activation and control, as well as investigating acute and chronic responses in the motor cortex in sport science. This technique can enhance cortical excitability, facilitate the learning process, and is considered a principal strategy for acquiring motor skills in training settings.
Article
Clinical Neurology
Mohd Faizal Mohd Zulkifly, Ornela Merkohitaj, Juergen Brockmoeller, Walter Paulus
Summary: The study investigated the impact of caffeine on brain plasticity and found that it increased motor cortex excitability in caffeine-naive subjects, enhanced PAS 25 effects, and affected alertness and motor evoked potentials under light deprivation. Time of day had no effect on tACS-induced plasticity in caffeine consumers.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Clinical Neurology
Leila Farnad, Ensiyeh Ghasemian-Shirvan, Mohsen Mosayebi-Samani, Min-Fang Kuo, Michael A. Nitsche
Summary: This study investigated the association between tDCS parameters and induced aftereffects on motor cortical excitability in older adults. The results showed that all active stimulation conditions significantly enhanced motor cortical excitability in both age groups, with no significant differences observed between the age groups. Prolonged plasticity was observed with higher stimulation intensities in the late-phase range.
Article
Psychology, Multidisciplinary
Ziyu Wang, Rongjuan Zhu, Xuqun You
Summary: This study manipulated task types and predictability to investigate the role of the DLPFC in task-switching performances, finding that anodal tDCS may have a stronger influence over the right DLPFC by changing the irrelevant task-set inhibition process. The right DLPFC is unlikely to act by performing exogenous adjustment of predictable task switching.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Neurosciences
Ziyu Wang, Ziye Kong, Chenlin Li, Jimin Liang, Xuqun You
Summary: Transcranial direct current stimulation (tDCS) was used to investigate the involvement of the parietal cortex in task switching. The study found that stimulation of the right parietal cortex can decrease performance in predictable task switching, suggesting its involvement in proactive cognitive processes.
Article
Neurosciences
Brittany K. Rurak, Julian P. Rodrigues, Brian D. Power, Peter D. Drummond, Ann-Maree Vallence
Summary: With advancing age, there is a decline in voluntary movement control, possibly due to reduced effective connectivity between the supplementary motor area and primary motor cortex. Older adults show lower SMA-M1 connectivity but better connectivity is associated with better bimanual motor control in this age group.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2021)
Article
Clinical Neurology
Ensiyeh Ghasemian-Shirvan, Mohsen Mosayebi-Samani, Leila Farnad, Min-Fang Kuo, Raf L. J. Meesen, Michael A. Nitsche
Summary: This study systematically explored the effects of cathodal transcranial direct current stimulation (tDCS) on motor cortex excitability in elderly individuals, and found that the effects varied with different stimulation parameters and age groups.
Review
Neurosciences
Dongting Tian, Shin-Ichi Izumi
Summary: Understanding cortical circuits is crucial in neuroscience and neurorehabilitation. Transcranial magnetic stimulation (TMS) allows non-invasive probing of neuronal activity. This review integrates evidence from neurocytology and neurophysiology to elucidate the relationship between microscopic neuronal landscape and macroscopic TMS outcome. A preliminary neuronal model of the human motor cortex is proposed, linking TMS mechanisms with neuronal activity.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Hiroyuki Matsuta, Tsuyoshi Shimomura, Takanori Kouchiyama, Minoru Fujiki
Summary: This study investigated the effects of continuous theta-burst stimulation (cTBS) on GABA levels in the brain and motor neurons. The results showed that cTBS could simultaneously increase GABA levels in the stimulated cortex and decrease GABA levels in the unstimulated cortex. This may be associated with the mechanism of cTBS in adjusting interhemispheric imbalance in stroke rehabilitation.
Article
Multidisciplinary Sciences
Sajjad Anoushiravani, Jaber Alizadehgoradel, Asgar Iranpour, Omid Yousefi Bilehsavar, Asghar Pouresmali, Michael A. Nitsche, Mohammad Ali Salehinejad, Mohsen Mosayebi-Samani, Maryam Zoghi
Summary: Professional sports performance heavily relies on the interaction between the brain and muscles during movement. The use of transcranial direct current stimulation (tDCS) can improve motor performance in athletes by modulating cortical excitability. In this study, bilateral anodal tDCS over the premotor cortex significantly improved power speed, strength coordination, and static and dynamic strength variables in professional gymnastics athletes.
SCIENTIFIC REPORTS
(2023)
Article
Neurosciences
Aline Iannone, Irene Santiago, Silvia T. Ajao, Joaquim Brasil-Neto, John C. Rothwell, Danny A. Spampinato
Summary: Transcranial direct current stimulation (tDCS) is a promising intervention in clinical and behavioral neuroscience, but its impact is limited by response variability. Focal stimulation over the primary motor cortex (M1) enhances skill learning and activates distinct pathways to M1, suggesting that it may improve outcomes in future behavior enhancement studies.
NEUROSCIENCE RESEARCH
(2022)
Review
Psychology, Clinical
Mauro Pettorruso, Andrea Miuli, Chiara Di Natale, Chiara Montemitro, Francesca Zoratto, Luisa De Risio, Giacomo d'Andrea, Pinhas N. Dannon, Giovanni Martinotti, Massimo di Giannantonio
Summary: Although heterogeneous in protocols and parameters, results from tDCS and TMS studies indicate that the stimulation (instead of inhibition) of prefrontal regions could be beneficial to combat dysfunctional gambling-related decision processes. Further research is needed to investigate connectivity changes and laterality issues of NIBS application in GD.
ADDICTIVE BEHAVIORS
(2021)
Article
Neurosciences
Alessandra Vergallito, Erica Varoli, Alberto Pisoni, Giulia Mattavelli, Lilia Del Mauro, Sarah Feroldi, Giuseppe Vallar, Leonor J. Romero Lauro
Summary: We studied the effects of transcranial direct current stimulation (tDCS) on cortical excitability using a combination of transcranial magnetic stimulation and electroencephalography (TMS-EEG). Anodal tDCS over the right Posterior Parietal Cortex (rPPC) increased cortical excitability, while cathodal tDCS had no effect. However, when an endogenous task-induced activation was present during stimulation, cathodal tDCS effectively modulated cortical excitability.
Review
Clinical Neurology
Peter J. Fried, Emiliano Santarnecchi, Andrea Antal, David Bartres-Faz, Sven Bestmann, Linda L. Carpenter, Pablo Celnik, Dylan Edwards, Faranak Farzan, Shirley Fecteau, Mark S. George, Bin He, Yun-Hee Kim, Letizia Leocani, Sarah H. Lisanby, Colleen Loo, Bruce Luber, Michael A. Nitsche, Walter Paulus, Simone Rossi, Paolo M. Rossini, John Rothwell, Alexander T. Sack, Gregor Thut, Yoshikazu Ugawa, Ulf Ziemann, Mark Hallett, Alvaro Pascual-Leone
Summary: This article provides recommendations for training practitioners in the safe and effective administration of NIBS techniques, covering three different types of practitioners. It discusses the basic and advanced knowledge and skills that practitioners need to possess, as well as recommendations for curriculum components. The article also encourages licensing and governing bodies to implement these guidelines.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Neurosciences
Alexia Dalski, Gyula Kovacs, Geza Gergely Ambrus
Summary: This study explored the neural signatures of face familiarity using event-related potentials decoding. The results showed that the familiarity effect of faces existed in different experiments, predominantly in the posterior and central regions of the right hemisphere. The shared familiarity effect suggests that the neural indicator of face familiarity may be independent of familiarization methods, participants, and stimuli.
Editorial Material
Behavioral Sciences
Teodora Vekony, Geza Gergely Ambrus, Karolina Janacsek, Dezso Nemeth
Summary: The role of the dorsolateral prefrontal cortex (DLPFC) in implicit sequence/statistical learning has been investigated. A recent study found that stimulating the DLPFC may not affect implicit sequence learning measured by the Serial Reaction Time (SRT) task. The authors suggest that previous results showing improved implicit sequence learning could be due to explicit awareness in the Alternating Serial Reaction Time (ASRT) task.
Article
Neurosciences
Sophie-Marie Rostalski, Jonathan Edward Robinson, Geza Gergely Ambrus, Patrick Johnston, Gyula Kovacs
Summary: This study investigated the image-invariant encoding mechanism of the occipito-temporal cortex in identity recognition using fMRI adaptation. The results supported recent multivariate pattern analysis studies, showing that the core face-processing areas of the occipito-temporal cortex have image-independent identity encoding.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Article
Clinical Neurology
Ivan Chakalov, Andrea Antal, Simon S. Eckardt, Walter Paulus, Leif Saager, Konrad Meissner, Mathias Bahr, Onnen Moerer, Caspar Stephani
Summary: The study investigated the effect of TMS parameters on diaphragmatic motor-evoked potentials and found that biphasic pulses require less charge and time compared to monophasic pulses for inducing diMEPs, making them more suitable for stimulating the diaphragm.
CLINICAL NEUROPHYSIOLOGY
(2022)
Review
Clinical Neurology
Hartwig R. Siebner, Klaus Funke, Aman S. Aberra, Andrea Antal, Sven Bestmann, Robert Chen, Joseph Classen, Marco Davare, Vincenzo Di Lazzaro, Peter T. Fox, Mark Hallett, Anke N. Karabanov, Janine Kesselheim, Mikkel M. Beck, Giacomo Koch, David Liebetanz, Sabine Meunier, Carlo Miniussi, Walter Paulus, Angel Peterchev, Traian Popa, Michael C. Ridding, Axel Thielscher, Ulf Ziemann, John C. Rothwell, Yoshikazu Ugawa
Summary: Transcranial (electro)magnetic stimulation (TMS) is a non-invasive method used to induce neural activity in the human brain. TMS generates a time-varying electric field in the brain, affecting cortical neurons and their action potentials. TMS primarily targets the axonal terminals in the cortical gyri, with additional stimulation of myelinated axon bends in the juxtacortical white matter. The response to TMS influences both local neuronal populations and connected networks in the target area, as well as causing stimulation in the peripheral nervous system. The interpretation of TMS effects requires caution, and understanding its underlying mechanisms is crucial for its scientific and therapeutic advancements.
CLINICAL NEUROPHYSIOLOGY
(2022)
Article
Neurosciences
Nicole E. Neef, Alexandra Korzeczek, Annika Primassin, Alexander Wolff von Gudenberg, Peter Dechent, Christian Heiner Riedel, Walter Paulus, Martin Sommer
Summary: Persistent stuttering is a common neurodevelopmental speech disorder that is often associated with cortical alterations and dysfunctional neural pathways. Therapy may impact different brain structures related to speech motor performance and social-emotional burden in individuals with persistent stuttering.
HUMAN BRAIN MAPPING
(2022)
Article
Multidisciplinary Sciences
Mohd Faizal Mohd Zulkifly, Albert Lehr, Daniel van de Velden, Asad Khan, Niels K. Focke, Carsten H. Wolters, Walter Paulus
Summary: Interindividual anatomical differences in the human cortex can lead to variability in the response of transcranial electrical stimulation methods. This study aimed to explore the effects of personalized multi-electrode stimulation montages on the somatosensory cortex using 140 Hz transcranial alternating current stimulation (tACS). The results showed a decrease in oscillatory mu-rhythms during and after tactile discrimination tasks, indicating the involvement of the somatosensory system. However, on a group level, tACS did not significantly modulate oscillatory power and evoked potential amplitudes.
Review
Neurosciences
Andrea Antal, Bruce Luber, Anna-Katharine Brem, Marom Bikson, Andre R. Brunoni, Roi Cohen Kadosh, Veljko Dubljevic, Shirley Fecteau, Florinda Ferreri, Agnes Floeel, Mark Hallett, Roy H. Hamilton, Christoph S. Herrmann, Michal Lavidor, Collen Loo, Caroline Lustenberger, Sergio Machado, Carlo Miniussi, Vera Moliadze, Michael A. Nitsche, Simone Rossi, Paolo M. Rossini, Emiliano Santarnecchi, Margitta Seeck, Gregor Thut, Zsolt Turi, Yoshikazu Ugawa, Ganesan Venkatasubramanian, Nicole Wenderoth, Anna Wexler, Ulf Ziemann, Walter Paulus
Summary: Attempts to enhance human memory and learning ability through brain stimulation methods have gained attention. The effectiveness of these methods, such as transcranial magnetic and electric stimulation, varies and depends on factors like equipment, operator skill, and parameters. Safety is ensured when following established protocols, but devices and protocols outside of these parameters cannot claim to be safe. Marketing of brain stimulation devices should adhere to ethical standards and not mislead users.
CLINICAL NEUROPHYSIOLOGY PRACTICE
(2022)
Editorial Material
Clinical Neurology
Walter Paulus
Summary: Fifty years ago, the study on delayed visual evoked response in optic neuritis opened a new era in neurophysiological diagnosis. The positive component P100, detected above the primary visual cortex at 100 ms using a chessboard stimulation introduced by Halliday et al., became the gold standard for detecting pathological remyelination of the optic nerve. However, the delay of this response still poses questions about the speed of information processing.
KLINISCHE NEUROPHYSIOLOGIE
(2022)
Article
Anatomy & Morphology
Alexia Dalski, Gyula Kovacs, Geza Gergely Ambrus
Summary: Recent research suggests that information about a person's identity and emotions is important for the neural signal of familiarity. This study examined whether such information is necessary for recognizing familiarity in visually familiar and perceptually familiar faces. The results showed that even without additional semantic or affective information, familiarity could still be decoded based on EEG patterns in a matching task. This indicates that the visual processing of familiar faces and perceptually familiarized faces involves similar mechanisms.
BRAIN STRUCTURE & FUNCTION
(2023)
Article
Behavioral Sciences
Chenglin Li, A. Mike Burton, Geza Gergely Ambrus, Gyula Kovacs
Summary: The study reveals that the neural representations of face familiarity emerge between 400-600 msec post-stimulus onset, especially for famous individuals. The correlation between decoding performance and behavioral familiarity was more reliable, occurred earlier and lasted longer when personally familiar faces and viewers' own faces were included in the analysis.
Article
Neurosciences
Alexia Dalski, Gyula Kovacs, Holger Wiese, Geza Gergely Ambrus
Summary: In this study, the researchers used cross-experiment multivariate classification of EEG patterns to provide evidence for a shared familiarity signal for faces. They further characterized the spatio-temporal properties of this signal and found that it is present for long-term personally familiar faces and is associated with acknowledged and concealed familiarity responses.
Article
Psychology, Biological
Gyula Kovacs, Chenglin Li, Geza Gergely Ambrus, A. Mike Burton
Summary: Recognizing a face as belonging to a given identity is important in everyday life. The neural dynamics of face identity processing are influenced by the degree of familiarity, with more familiar faces being decoded with higher accuracy and for longer durations. However, one's own face only benefits from processing advantages in a relatively late time window.
Article
Neurosciences
Hannah Klink, Daniel Kaiser, Rico Stecher, Geza G. Ambrus, Gyula Kovacs
Summary: This study investigates the neural dynamics of familiarity with personally familiar scenes. The results show that familiarity can be decoded from EEG data for scenes and faces, but scenes have delayed processing compared to faces. Familiarity information affects recognition from 200ms and enhances category representations in early and late processing stages.
Article
Neurosciences
Song Xue, Feng Kong, Yiying Song, Jia Liu
Summary: This study used resting-state functional magnetic resonance imaging to explore the relationship between individual's spontaneous neural activity and social interaction anxiety in a nonclinical population. The results showed that social interaction anxiety was correlated with the fractional amplitude of low-frequency fluctuations in several brain regions, and that emotional intelligence partially mediated this relationship. This study provides evidence for the neural basis of social interaction anxiety in the normal population and highlights the role of emotional intelligence in this anxiety.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Katsuyuki Yamaguchi, Takuya Yazawa
Summary: This study provides morphometric data on the development of the human medullary arcuate nucleus (AN) by examining the brains of preterm and perinatal infants. The results show that AN morphology demonstrates asymmetry and individual variability during the fetal period. The volume and neuronal number of AN increase exponentially with age, while neuronal density decreases exponentially. The AN may undergo neuron death and neuroblasts production after mid-gestation.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Zhan Zhou, Weixin Dai, Tianxiao Liu, Min Shi, Yi Wei, Lifei Chen, Yubo Xie
Summary: Studies have shown that propofol-induced neurotoxicity is caused by disruption of mitochondrial fission and fusion, leading to an energy supply imbalance for developing neurons. Healthy mitochondria released by astrocytes can migrate to compromised neurons to mitigate propofol-induced neurotoxicity, but the exact mechanisms involved still need further clarification.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
An Chen, Song Hao, Yongpeng Han, Yang Fang, Yibei Miao
Summary: This study explores the efficacy of two forms of BCI attention training games and finds that physical games may be more effective than video games. The research also offers valuable insights for future game design from a neuroscience perspective.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Lina Liu, Luran Liu, Yunting Lu, Tianyuan Zhang, Wenting Zhao
Summary: This study reveals that GDI1 serves as a potential diagnostic biomarker for AD and inhibition of GDI1 can attenuate Aβ-induced neurotoxicity. The findings offer new insights for the treatment of AD.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Zahra Gholami, Ava Soltani Hekmat, Ali Abbasi, Kazem Javanmardi
Summary: This study investigated the effects of alamandine on allodynia in a rat model and found the presence of MrgD receptors in the vlPAG and RVM regions. Microinjection of alamandine resulted in a significant increase in paw withdrawal threshold and could be blocked by an MrgD receptor antagonist. Upregulation of MrgD receptor expression following allodynia induction suggests a potential compensatory mechanism in response to pain.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Mingliang Xu, Lei Xia, Junjie Li, Yehong Du, Zhifang Dong
Summary: This study found that DHF effectively alleviates sevoflurane-induced cognitive impairment in developing mice by restoring the balance between tau O-GlcNAcylation and phosphorylation. Therefore, DHF has the potential to be a therapeutic agent for treating cognitive impairment associated with anesthetics, such as sevoflurane.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Tsubasa Mitsutake, Hisato Nakazono, Takanori Taniguchi, Hisayoshi Yoshizuka, Maiko Sakamoto
Summary: The posterior parietal cortex plays a crucial role in postural stability, and transcranial electrical stimulation of this region can modulate physical control responses. This study found that cathodal stimulation significantly decreased joint angular velocity in multiple directions, while there were no significant differences with transcranial random noise stimulation.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Xishuai Yang, Wei Zhang, Xueli Chang, Zuopeng Li, Runquan Du, Junhong Guo
Summary: This study aims to evaluate the efficacy of low-dose rituximab (RTX) in patients with muscle-specific kinase antibody positive myasthenia gravis (MuSK-MG). The results showed that low-dose RTX treatment led to significant improvements in clinical symptoms and quality of life for patients with MuSK-MG.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Jian Zhang, Shunyuan Guo, Rong Tao, Fan Wang, Yihong Xie, Huizi Wang, Lan Ding, Yuejian Shen, Xiaoli Zhou, Junli Feng, Qing Shen
Summary: This study established an Alzheimer's disease (AD) model of zebrafish induced by AlCl3 and found that marine-derived plasmalogens (Pls) could alleviate cognitive impairments of AD zebrafish by reversing athletic impairment and altering the expression levels of genes related to oxidative stress, ferroptosis, synaptic dysfunction, and apoptosis.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Lu Li, Jiaqi Ren, Qi Fang, Liqiang Yu, Jintao Wang
Summary: ICU-AW is a common and severe neuromuscular complication in critically ill patients. Electrophysiological examination is essential for accurate diagnosis and early prediction of the disease. This study aimed to establish and validate an ICU-AW predictive model in SIRS patients, providing a practical tool for early clinical prediction.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Ahmad Alipour, Roghayeh Mohammadi
Summary: The present study aimed to investigate the separate and combined effects of anodal transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) and left dorsolateral prefrontal cortex (F3) regions on pain relief in patients with type-2 diabetes suffering from neuropathic pain (NP). The results showed that tDCS had the potential to induce pain relief in patients with type-2 diabetes suffering from NP. The mean perceived pain intensity in the posttest was lower in the M1 stimulation group than in the F3 stimulation group. However, more trials with larger sample sizes are necessary to define clinically relevant effects.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Eduardo J. Fusse, Franciele F. Scarante, Maria A. Vicente, Mariana M. Marrubia, Flavia Turcato, Davi S. Scomparin, Melissa A. Ribeiro, Maria J. Figueiredo, Tamires A. V. Brigante, Francisco S. Guimaraes, Alline C. Campos
Summary: Repeated exposure to psychosocial stress alters the endocannabinoid system and affects brain regions associated with emotional distress. Enhancing the effects of endocannabinoids through pharmacological inhibition induces an anti-stress behavioral effect, possibly mediated by the mTOR signaling pathway.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Giulia Agostoni, Luca Bischetti, Federica Repaci, Margherita Bechi, Marco Spangaro, Irene Ceccato, Elena Cavallini, Luca Fiorentino, Francesca Martini, Jacopo Sapienza, Mariachiara Buonocore, Michele Francesco D'Incalci, Federica Cocchi, Carmelo Guglielmino, Roberto Cavallaro, Marta Bosia, Valentina Bambini
Summary: This study found a general impairment in humor comprehension in individuals with schizophrenia, with mental jokes being more difficult for both patients and controls. Humor comprehension was closely associated with the patients' overall pragmatic and linguistic profile, while the association with Theory of Mind (ToM) was minimal. Another notable finding was the increased appreciation of humor in individuals with schizophrenia, who rated jokes as funnier than controls did, regardless of whether they were correctly or incorrectly completed. The funniness ratings were not predicted by any measure, suggesting a dimension of humor untied to cognition or psychopathology.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Xiuping Gong, Qi Li, Yang Liu
Summary: This study demonstrates that Sev targets CREBBP to inhibit ALG13 transcription, leading to hippocampal damage and cognitive impairment.
NEUROSCIENCE LETTERS
(2024)