In- silico evaluation of bioactive compounds from selected medicinal plants from Southern Nigeria against hepatitis C virus genotype 1 RNA-directed RNA polymerase

A score years’ update in the synthesis and biological evaluation of medicinally important 2-pyridones

(2022) Sarita Sangwan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, and bioactivity of ferulic acid derivatives containing an β-amino alcohol

(2022) Ali Dai et al.   BMC Chemistry

Evaluation of Antimicrobial and Chemopreventive Properties and Phytochemical Analysis of Solanum nigrum L. Aerial Parts and Root Extracts

(2022) Elżbieta Gębarowska et al.   Applied Sciences-Basel

COVID-19 pandemic: lessons learned from more than a century of pandemics and current vaccine development for pandemic control

(2021) Philippe Buchy et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

The genus Jatropha (Euphorbiaceae): A review on secondary chemical metabolites and biological aspects

(2020) Noelly Bastos Cavalcante et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP review

(2020) Cordula Stillhart et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Bioactive Natural Antivirals: An Updated Review of the Available Plants and Isolated Molecules

(2020) Syam Mohan et al.   MOLECULES

Bioactive Ingredients in Chinese Herbal Medicines That Target Non-coding RNAs: Promising New Choices for Disease Treatment

(2019) Yan Dong et al.   Frontiers in Pharmacology

Phytochemical profiling and antiviral activity of Ajuga bracteosa, Ajuga parviflora, Berberis lycium and Citrus lemon against Hepatitis C Virus

(2018) Tahir Yousaf et al.   MICROBIAL PATHOGENESIS

Annona muricata: A comprehensive review on its traditional medicinal uses, phytochemicals, pharmacological activities, mechanisms of action and toxicity

(2018) Ana V. Coria-Téllez et al.   Arabian Journal of Chemistry

Synergism of Plant Compound With Traditional Antimicrobials Against Streptococcus spp. Isolated From Bovine Mastitis

(2018) Natasha L. Maia et al.   Frontiers in Microbiology

Natural Medicines Used in the Traditional Tibetan Medical System for the Treatment of Liver Diseases

(2018) Qi Li et al.   Frontiers in Pharmacology

Predicting Fraction Unbound in Human Plasma from Chemical Structure: Improved Accuracy in the Low Value Ranges

(2018) Reiko Watanabe et al.   MOLECULAR PHARMACEUTICS

Approaches, Progress, and Challenges to Hepatitis C Vaccine Development

(2018) Justin R. Bailey et al.   GASTROENTEROLOGY

Effects of Chinese herbal medicine therapy on survival and hepatic outcomes in patients with hepatitis C virus infection in Taiwan

(2018) Fuu-Jen Tsai et al.   PHYTOMEDICINE

Therapeutic potential of Taraxacum officinale against HCV NS5B polymerase: In-vitro and In silico study

(2016) Sidra Rehman et al.   BIOMEDICINE & PHARMACOTHERAPY

P-glycoprotein and its role in drug-drug interactions

(2016) Andrew Finch et al.   Australian Prescriber

Hepatitis C virus prevalence and serotypes associated with HIV in The Gambia

(2016) C. I. Mboto et al.   BRITISH JOURNAL OF BIOMEDICAL SCIENCE

Drug-Induced Liver Injury

(2015) Kurt Fisher et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Antiviral Natural Products Against Chronic Hepatitis B: Recent Developments

(2015) Mohammad K. Parvez et al.   CURRENT PHARMACEUTICAL DESIGN

pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures

(2015) Douglas E. V. Pires et al.   JOURNAL OF MEDICINAL CHEMISTRY

Using the Hepatitis C Virus RNA-Dependent RNA Polymerase as a Model to Understand Viral Polymerase Structure, Function and Dynamics

(2015) Ester Sesmero et al.   Viruses-Basel

Clinical development success rates for investigational drugs

(2014) Michael Hay et al.   NATURE BIOTECHNOLOGY

The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety

(2014) Martins Ekor   Frontiers in Pharmacology

Identification of Novel Small Molecules as Inhibitors of Hepatitis C Virus by Structure-Based Virtual Screening

(2013) Jing Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In silico Prediction of Chemical Ames Mutagenicity

(2012) Congying Xu et al.   Journal of Chemical Information and Modeling

admetSAR: A Comprehensive Source and Free Tool for Assessment of Chemical ADMET Properties

(2012) Feixiong Cheng et al.   Journal of Chemical Information and Modeling

Novel Natural Inhibitors of CYP1A2 Identified by in Silico and in Vitro Screening

(2011) Ruixin Zhu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase

(2011) Michael J. Sofia et al.   JOURNAL OF MEDICINAL CHEMISTRY

In-vitro antiviral activity of Solanum nigrum against Hepatitis C Virus

(2011) Tariq Javed et al.   Virology Journal

The graphical representation of ADME-related molecule properties for medicinal chemists

(2010) Timothy J. Ritchie et al.   DRUG DISCOVERY TODAY

New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme

(2009) Bo Wang et al.   DRUG METABOLISM REVIEWS

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Functional Characterization of Fingers Subdomain-specific Monoclonal Antibodies Inhibiting the Hepatitis C Virus RNA-dependent RNA Polymerase

(2008) Andrei Nikonov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY