Rationally designed molecular beacons for bioanalytical and biomedical applications

Smart Vesicle Kit for In Situ Monitoring of Intracellular Telomerase Activity Using a Telomerase-Responsive Probe

(2014) Ruocan Qian et al.   ANALYTICAL CHEMISTRY

Universal Surface-Enhanced Raman Scattering Amplification Detector for Ultrasensitive Detection of Multiple Target Analytes

(2014) Jing Zheng et al.   ANALYTICAL CHEMISTRY

A Versatile Activatable Fluorescence Probing Platform for Cancer Cells in Vitro and in Vivo Based on Self-Assembled Aptamer/Carbon Nanotube Ensembles

(2014) Lv’an Yan et al.   ANALYTICAL CHEMISTRY

Exonuclease III-Aided Autocatalytic DNA Biosensing Platform for Immobilization-Free and Ultrasensitive Electrochemical Detection of Nucleic Acid and Protein

(2014) Shufeng Liu et al.   ANALYTICAL CHEMISTRY

Label-free Molecular Beacons for Biomolecular Detection

(2014) Xiaohong Tan et al.   ANALYTICAL CHEMISTRY

Single-point mutation detection in RNA extracts using gold nanoparticles modified with hydrophobic molecular beacon-like structures

(2014) Alfonso Latorre et al.   CHEMICAL COMMUNICATIONS

DNA Colorimetric Logic Gates Based on Triplex–Helix Molecular Switch

(2014) Wan Gao et al.   Journal of Physical Chemistry C

A Robust Probe for Lighting Up Intracellular Telomerase via Primer Extension To Open a Nicked Molecular Beacon

(2014) Ruocan Qian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thioflavin T as a fluorescence light-up probe for G4 formation

(2014) Amandine Renaud de la Faverie et al.   NUCLEIC ACIDS RESEARCH

Engineering of Switchable Aptamer Micelle Flares for Molecular Imaging in Living Cells

(2013) Cuichen Wu et al.   ACS Nano

A Spherical Nucleic Acid Platform Based on Self-Assembled DNA Biopolymer for High-Performance Cancer Therapy

(2013) Jing Zheng et al.   ACS Nano

New probe design strategy by cooperation of metal/DNA-ligation and supermolecule inclusion interaction: application to detection of mercury ions(II)

(2013) Xiaoxia Gao et al.   ANALYST

Molecule-binding dependent assembly of split aptamer and γ-cyclodextrin: A sensitive excimer signaling approach for aptamer biosensors

(2013) Fen Jin et al.   ANALYTICA CHIMICA ACTA

Versatile DNAzyme-Based Amplified Biosensing Platforms for Nucleic Acid, Protein, and Enzyme Activity Detection

(2013) Xu-Hua Zhao et al.   ANALYTICAL CHEMISTRY

Dual-Targeted Nanocarrier Based on Cell Surface Receptor and Intracellular mRNA: An Effective Strategy for Cancer Cell Imaging and Therapy

(2013) Wei Pan et al.   ANALYTICAL CHEMISTRY

Label-Free Colorimetric Aptasensor Based on Nicking Enzyme Assisted Signal Amplification and DNAzyme Amplification for Highly Sensitive Detection of Protein

(2013) Yong Huang et al.   ANALYTICAL CHEMISTRY

DNA Micelle Flares for Intracellular mRNA Imaging and Gene Therapy

(2013) Tao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Adenosine-based molecular beacons as light-up probes for sensing heparin in plasma

(2013) Chia-Yin Kuo et al.   CHEMICAL COMMUNICATIONS

Backbone-modified molecular beacons for highly sensitive and selective detection of microRNAs based on duplex specific nuclease signal amplification

(2013) Xiaoyan Lin et al.   CHEMICAL COMMUNICATIONS

A Targeted, Self-Delivered, and Photocontrolled Molecular Beacon for mRNA Detection in Living Cells

(2013) Liping Qiu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics

(2013) G. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Consecutive Targetable Smart Nanoprobe for Molecular Recognition of Cytoplasmic microRNA in Metastatic Breast Cancer

(2012) Eunjung Kim et al.   ACS Nano

Assembly of Aptamer Switch Probes and Photosensitizer on Gold Nanorods for Targeted Photothermal and Photodynamic Cancer Therapy

(2012) Jian Wang et al.   ACS Nano

Ultrasensitive Solution-Phase Electrochemical Molecular Beacon-Based DNA Detection with Signal Amplification by Exonuclease III-Assisted Target Recycling

(2012) Feng Xuan et al.   ANALYTICAL CHEMISTRY

A Multicolor Nanoprobe for Detection and Imaging of Tumor-Related mRNAs in Living Cells

(2012) Na Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Target-Cell-Specific Delivery, Imaging, and Detection of Intracellular MicroRNA with a Multifunctional SnO2Nanoprobe

(2012) Haifeng Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A disulfide bound-molecular beacon as a fluorescent probe for the detection of reduced glutathione and its application in cells

(2012) Yingshu Guo et al.   CHEMICAL COMMUNICATIONS

A room-temperature adenosine-based molecular beacon for highly sensitive detection of nucleic acids

(2012) Yen-Hsiu Lin et al.   CHEMICAL COMMUNICATIONS

Fabricating a Reversible and Regenerable Raman-Active Substrate with a Biomolecule-Controlled DNA Nanomachine

(2012) Jing Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

l-DNA Molecular Beacon: A Safe, Stable, and Accurate Intracellular Nano-thermometer for Temperature Sensing in Living Cells

(2012) Guoliang Ke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thioflavin T as an Efficient Inducer and Selective Fluorescent Sensor for the Human Telomeric G-Quadruplex DNA

(2012) Jyotirmayee Mohanty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Graphene–DNAzyme Based Biosensor for Amplified Fluorescence “Turn-On” Detection of Pb2+with a High Selectivity

(2011) Xu-Hua Zhao et al.   ANALYTICAL CHEMISTRY

Molecular Beacon Based Bioassay for Highly Sensitive and Selective Detection of Nicotinamide Adenine Dinucleotide and the Activity of Alanine Aminotransferase

(2011) Zhiwen Tang et al.   ANALYTICAL CHEMISTRY

Design of a Room-Temperature Phosphorescence-Based Molecular Beacon for Highly Sensitive Detection of Nucleic Acids in Biological Fluids

(2011) Jishan Li et al.   ANALYTICAL CHEMISTRY

Bifunctional Colorimetric Oligonucleotide Probe Based on a G-Quadruplex DNAzyme Molecular Beacon

(2011) Libing Zhang et al.   ANALYTICAL CHEMISTRY

Design of Aptamer-Based Sensing Platform Using Triple-Helix Molecular Switch

(2011) Jing Zheng et al.   ANALYTICAL CHEMISTRY

The use of polyethylenimine-grafted graphene nanoribbon for cellular delivery of locked nucleic acid modified molecular beacon for recognition of microRNA

(2011) Haifeng Dong et al.   BIOMATERIALS

Caged molecular beacons: controlling nucleic acid hybridization with light

(2011) Chunming Wang et al.   CHEMICAL COMMUNICATIONS

A tumor mRNA-dependent gold nanoparticle–molecular beacon carrier for controlled drug release and intracellular imaging

(2011) Guangming Qiao et al.   CHEMICAL COMMUNICATIONS

A tumor mRNA-mediated bi-photosensitizer molecular beacon as an efficient imaging and photosensitizing agent

(2011) Yuan Gao et al.   CHEMICAL COMMUNICATIONS

Aptamer-Based Switchable Nanovalves for Stimuli-Responsive Drug Delivery

(2011) Veli C. Özalp et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Label-Free, Quadruplex-Based Functional Molecular Beacon (LFG4-MB) for Fluorescence Turn-On Detection of DNA and Nuclease

(2011) Dan Hu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Simultaneous Detection of Intracellular Tumor mRNA with Bi-Color Imaging Based on a Gold Nanoparticle/Molecular Beacon

(2011) Guangming Qiao et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Ligation-Triggered DNAzyme Cascade for Amplified Fluorescence Detection of Biological Small Molecules with Zero-Background Signal

(2011) Li-Min Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration

(2011) H. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleic Acid-Gold Nanoparticle Conjugates as Mimics of microRNA

(2011) Liangliang Hao et al.   Small

Catalytic and Molecular Beacons for Amplified Detection of Metal Ions and Organic Molecules with High Sensitivity

(2010) Xiao-Bing Zhang et al.   ANALYTICAL CHEMISTRY

Modulating Molecular Level Space Proximity: A Simple and Efficient Strategy to Design Structured DNA Probes

(2010) Jing Zheng et al.   ANALYTICAL CHEMISTRY

Silver Ions-Mediated Conformational Switch: Facile Design of Structure-Controllable Nucleic Acid Probes

(2010) Yongxiang Wang et al.   ANALYTICAL CHEMISTRY

DNAzyme Molecular Beacon Probes for Target-Induced Signal-Amplifying Colorimetric Detection of Nucleic Acids

(2010) Rongzhan Fu et al.   ANALYTICAL CHEMISTRY

Molecular Beacon-Based Junction Probes for Efficient Detection of Nucleic Acids via a True Target-Triggered Enzymatic Recycling Amplification

(2010) Rong-Mei Kong et al.   ANALYTICAL CHEMISTRY

A Highly Sensitive, Excimer-Controlled Molecular Beacon

(2010) Robert Häner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular beacon–quantum dot–Au nanoparticle hybrid nanoprobes for visualizing virus replication in living cells

(2010) Hsiao-Yun Yeh et al.   CHEMICAL COMMUNICATIONS

Increasing the Sensitivity and Single-Base Mismatch Selectivity of the Molecular Beacon Using Graphene Oxide as the “Nanoquencher”

(2010) Chun-Hua Lu et al.   CHEMISTRY-A EUROPEAN JOURNAL

NUPACK: Analysis and design of nucleic acid systems

(2010) Joseph N. Zadeh et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Hairpin DNA-Functionalized Gold Colloids for the Imaging of mRNA in Live Cells

(2010) Ashwath Jayagopal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aptamer-conjugated nanomaterials for bioanalysis and biotechnology applications

(2010) Tao Chen et al.   Nanoscale

Aptamer−DNAzyme Hairpins for Amplified Biosensing

(2009) Carsten Teller et al.   ANALYTICAL CHEMISTRY

In-Stem Molecular Beacon Containing a Pseudo Base Pair of Threoninol Nucleotides for the Removal of Background Emission

(2009) Hiromu Kashida et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorescent Color Readout of DNA Hybridization with Thiazole Orange as an Artificial DNA Base

(2009) Sina Berndl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gold-Nanoparticle-Based Multicolor Nanobeacons for Sequence-Specific DNA Analysis

(2009) Shiping Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular beacon-functionalized gold nanoparticles as probes in dry-reagent strip biosensor for DNA analysis

(2009) Xun Mao et al.   CHEMICAL COMMUNICATIONS

Phthalocyanine Dimerization-Based Molecular Beacons Using Near-IR Fluorescence

(2009) Irina V. Nesterova et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gene Regulation with Polyvalent siRNA−Nanoparticle Conjugates

(2009) David A. Giljohann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-DNA Molecule Nanomotor Regulated by Photons

(2009) Huaizhi Kang et al.   NANO LETTERS

Sensitive fluorescence detection of nucleic acids based on isothermal circular strand-displacement polymerization reaction

(2009) Qiuping Guo et al.   NUCLEIC ACIDS RESEARCH

Molecular Engineering of DNA: Molecular Beacons

(2008) Kemin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design of a novel molecular beacon: modification of the stem with artificially genetic alphabet

(2008) Pinpin Sheng et al.   CHEMICAL COMMUNICATIONS

Reversible molecular switching of molecular beacon: controlling DNA hybridization kinetics and thermodynamics using mercury(ii) ions

(2008) Ronghua Yang et al.   CHEMICAL COMMUNICATIONS

Regulation of Singlet Oxygen Generation Using Single-Walled Carbon Nanotubes

(2008) Zhi Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbon Nanotube-Quenched Fluorescent Oligonucleotides: Probes that Fluoresce upon Hybridization

(2008) Ronghua Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzymatic signal amplification of molecular beacons for sensitive DNA detection

(2008) Jianwei Jeffery Li et al.   NUCLEIC ACIDS RESEARCH

Bis-pyrene-labeled molecular beacon: A monomer–excimer switching probe for the detection of DNA base alteration

(2007) Kazushige Yamana et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Pyrene Excimer Signaling Molecular Beacons for Probing Nucleic Acids

(2007) Patrick Conlon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY