Conivaptan, a Selective Arginine Vasopressin V1a and V2 Receptor Antagonist Attenuates Global Cerebral Edema Following Experimental Cardiac Arrest via Perivascular Pool of Aquaporin-4

Arginine-Vasopressin Receptor Blocker Conivaptan Reduces Brain Edema and Blood-Brain Barrier Disruption after Experimental Stroke in Mice

(2015) Emil Zeynalov et al.   PLoS One

Sexually Dimorphic Response of TRPM2 Inhibition Following Cardiac Arrest-Induced Global Cerebral Ischemia in Mice

(2013) S. Nakayama et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Aquaporin water channels in the nervous system

(2013) Marios C. Papadopoulos et al.   NATURE REVIEWS NEUROSCIENCE

Physiological Roles of Aquaporin-4 in Brain

(2013) Erlend A. Nagelhus et al.   PHYSIOLOGICAL REVIEWS

The role of vasopressin V1A receptors in cytotoxic brain edema formation following brain injury

(2012) Andrea Kleindienst et al.   ACTA NEUROCHIRURGICA

SK2 Channels Are Neuroprotective for Ischemia-Induced Neuronal Cell Death

(2011) Duane Allen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Arginine-vasopressin V1a receptor inhibition improves neurologic outcomes following an intracerebral hemorrhagic brain injury

(2011) Anatol Manaenko et al.   NEUROCHEMISTRY INTERNATIONAL

Open-Label Randomized Trial of the Safety and Efficacy of a Single Dose Conivaptan to Raise Serum Sodium in Patients with Traumatic Brain Injury

(2011) Christopher Galton et al.   Neurocritical Care

Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet

(2011) N. N. Haj-Yasein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vasopressin V 1a Receptors Mediate Posthemorrhagic Systemic Hypertension Thereby Determining Rebleeding Rate and Outcome After Experimental Subarachnoid Hemorrhage

(2011) Konstantin Hockel et al.   STROKE

Testosterone exacerbates neuronal damage following cardiac arrest and cardiopulmonary resuscitation in mouse

(2010) Takaaki Nakano et al.   BRAIN RESEARCH

A Bolus of Conivaptan Lowers Intracranial Pressure in a Patient with Hyponatremia after Traumatic Brain Injury

(2010) Rajat Dhar et al.   Neurocritical Care

Targeted Overexpression of Endothelin-1 in Astrocytes Leads to More Severe Cytotoxic Brain Edema and Higher Mortality

(2009) Patrick Ka Kit Yeung et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Role of Vasopressin V1a and V2 Receptors for the Development of Secondary Brain Damage after Traumatic Brain Injury in Mice

(2009) Raimund Trabold et al.   JOURNAL OF NEUROTRAUMA

Inhibition of Aquaporin-1 and Aquaporin-4 Water Permeability by a Derivative of the Loop Diuretic Bumetanide Acting at an Internal Pore-Occluding Binding Site

(2009) E. Migliati et al.   MOLECULAR PHARMACOLOGY

Non-Peptide Arginine-Vasopressin Antagonists (Vaptans) for the Treatment of Hyponatremia in Neurocritical Care: A New Alternative?

(2009) Jeremy D. Fields et al.   Neurocritical Care

Arginine-Vasopressin V1 but not V2 Receptor Antagonism Modulates Infarct Volume, Brain Water Content, and Aquaporin-4 Expression Following Experimental Stroke

(2009) Xiaoqin Liu et al.   Neurocritical Care

The perivascular pool of aquaporin-4 mediates the effect of osmotherapy in postischemic cerebral edema*

(2008) Emil Zeynalov et al.   CRITICAL CARE MEDICINE

Non-peptide arginine-vasopressin antagonists: the vaptans

(2008) Guy Decaux et al.   LANCET