Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model

Intrinsic Astrocyte Heterogeneity Influences Tumor Growth in Glioma Mouse Models

(2016) David M. Irvin et al.   BRAIN PATHOLOGY

Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide

(2016) Ralf S. Schmid et al.   NEURO-ONCOLOGY

Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma

(2016) Juli R. Bagó et al.   Nature Communications

Gap junctions modulate glioma invasion by direct transfer of microRNA

(2015) Xiaoting Hong et al.   Oncotarget

Glial scar and immune cell involvement in tissue remodeling and repair following acute CNS injuries

(2014) Catarina Raposo et al.   GLIA

Fibroblast Growth Factor 4 Is Required but not Sufficient for the Astrocyte Dedifferentiation

(2014) Guo-Dong Feng et al.   MOLECULAR NEUROBIOLOGY

Contemporary murine models in preclinical astrocytoma drug development

(2014) Robert S. McNeill et al.   NEURO-ONCOLOGY

Cell transcriptional state alters genomic patterns of DNA double-strand break repair in human astrocytes

(2014) Raymund L. Yong et al.   Nature Communications

Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice

(2014) Robert S. McNeill et al.   Jove-Journal of Visualized Experiments

Regulation and dysregulation of astrocyte activation and implications in tumor formation

(2013) Chunzhang Yang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Traumatic scratch injury in astrocytes triggers calcium influx to activate the JNK/c-Jun/AP-1 pathway and switch on GFAP expression

(2013) Kai Gao et al.   GLIA

Factors associated with a higher rate of distant failure after primary treatment for glioblastoma

(2013) Sonia Tejada et al.   JOURNAL OF NEURO-ONCOLOGY

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Cooperativity between MAPK and PI3K signaling activation is required for glioblastoma pathogenesis

(2013) M. Vitucci et al.   NEURO-ONCOLOGY

Evolutionary etiology of high-grade astrocytomas

(2013) Y. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-Associated Macrophages in Glioma: Friend or Foe?

(2013) Benjamin C. Kennedy et al.   Journal of Oncology

Real-time multi-modality imaging of glioblastoma tumor resection and recurrence

(2012) Shawn Hingtgen et al.   JOURNAL OF NEURO-ONCOLOGY

Self-Renewal and Differentiation of Reactive Astrocyte-Derived Neural Stem/Progenitor Cells Isolated from the Cortical Peri-Infarct Area after Stroke

(2012) I. S. Shimada et al.   JOURNAL OF NEUROSCIENCE

In vivo models of primary brain tumors: pitfalls and perspectives

(2012) P. C. Huszthy et al.   NEURO-ONCOLOGY

Astrocyte-Specific Expression Patterns Associated with the PDGF-Induced Glioma Microenvironment

(2012) Amanda M. Katz et al.   PLoS One

 -Catenin signaling initiates the activation of astrocytes and its dysregulation contributes to the pathogenesis of astrocytomas

(2012) C. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sonic hedgehog released from scratch-injured astrocytes is a key signal necessary but not sufficient for the astrocyte de-differentiation

(2012) Hao Yang et al.   Stem Cell Research

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Immune microenvironments in solid tumors: new targets for therapy

(2011) S. L. Shiao et al.   GENES & DEVELOPMENT

The brain tumor microenvironment

(2011) Nikki A. Charles et al.   GLIA

The stem cell potential of glia: lessons from reactive gliosis

(2011) Stefanie Robel et al.   NATURE REVIEWS NEUROSCIENCE

Astrocyte Elevated Gene-1 Upregulates Matrix Metalloproteinase-9 and Induces Human Glioma Invasion

(2010) Liping Liu et al.   CANCER RESEARCH

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy

(2009) Mary Lou Affronti et al.   CANCER

Glioblastoma multiforme: a review of where we have been and where we are going

(2009) Cory Adamson et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma in elderly patients

(2008) G. Minniti et al.   JOURNAL OF NEURO-ONCOLOGY

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain

(2008) A. Buffo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA