The anticancer potential of chemical constituents of Moringa oleifera targeting CDK-2 inhibition in estrogen receptor positive breast cancer using in-silico and in vitro approches

Ellagic Acid Controls Cell Proliferation and Induces Apoptosis in Breast Cancer Cells via Inhibition of Cyclin-Dependent Kinase 6

(2020) Mohd Yousuf et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phytochemical profiling, antioxidant and antiproliferation potential of Euphorbia milii var.: Experimental analysis and in-silico validation

(2020) Talha Ali Chohan et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Novel CDK2 Inhibitors for Treating Cancer

(2020) Ram W. Sabnis   ACS Medicinal Chemistry Letters

Chlorogenic acid induces apoptosis, inhibits metastasis and improves antitumor immunity in breast cancer via the NF‑κB signaling pathway

(2020) Anqi Zeng et al.   ONCOLOGY REPORTS

Mechanisms of CDK4/6 Inhibitor Resistance in Luminal Breast Cancer

(2020) Zhen Li et al.   Frontiers in Pharmacology

The nature of ligand efficiency

(2019) Peter W. Kenny   Journal of Cheminformatics

Kaempferol: A Key Emphasis to Its Anticancer Potential

(2019) Muhammad Imran et al.   MOLECULES

CDK4/6 inhibitors in breast cancer therapy: Current practice and future opportunities

(2018) Filipa Lynce et al.   PHARMACOLOGY & THERAPEUTICS

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Two Decades under the Influence of the Rule of Five and the Changing Properties of Approved Oral Drugs

(2018) Michael D. Shultz   JOURNAL OF MEDICINAL CHEMISTRY

FDA approves Novartis's CDK4/6 inhibitor

(2017) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

(2017) Hongchao Pan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Multiple CDK inhibitor dinaciclib suppresses neuroblastoma growth via inhibiting CDK2 and CDK9 activity

(2016) Zhenghu Chen et al.   Scientific Reports

In vitro Evaluation of Cytotoxic Activities of Essential Oil from Moringa oleifera Seeds on HeLa, HepG2, MCF-7, CACO-2 and L929 Cell Lines

(2015) Elsayed Ahmed Elsayed et al.   Asian Pacific Journal of Cancer Prevention

Broad targeting of angiogenesis for cancer prevention and therapy

(2015) Zongwei Wang et al.   SEMINARS IN CANCER BIOLOGY

Antioxidant and anticancer activities of Moringa oleifera leaves

(2014) Charoensin Suphachai   Journal of Medicinal Plants Research

Preparative Isolation of Bioactive Nitrile Glycoside “Niazirin” from the Fruits ofMoringa oleiferaUsing Fast Centrifugal Partition Chromatography

(2011) Anupam Maurya et al.   SEPARATION SCIENCE AND TECHNOLOGY

Dinaciclib (SCH 727965), a Novel and Potent Cyclin-Dependent Kinase Inhibitor

(2010) David Parry et al.   MOLECULAR CANCER THERAPEUTICS

Centrosome-associated regulators of the G2/M checkpoint as targets for cancer therapy

(2009) Yingmei Wang et al.   Molecular Cancer

Cyclin-dependent kinases and cell-cycle transitions: does one fit all?

(2008) Helfrid Hochegger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY