Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 357, Issue 2-3, Pages 594-600Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201400942
Keywords
acylation; C-H activation; indoles; indolines; palladium
Categories
Funding
- National Research Foundation of Korea (NRF) - Ministry of Education, Science and Technology [2013R1A2A2A01005249]
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The palladium-catalyzed oxidative acylation of indolines at the C-7 position with aldehydes or alcohols via C-H bond activation is described. This protocol represents a facile access to 7-acylated indolines, which can be readily transformed into 7-acylated indoles with diverse biological properties.
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