Internetwork competition for monomers governs actin cytoskeleton organization

Profilin Interaction with Actin Filament Barbed End Controls Dynamic Instability, Capping, Branching, and Motility

(2016) Julien Pernier et al.   DEVELOPMENTAL CELL

Avoiding artefacts when counting polymerized actin in live cells with LifeAct fused to fluorescent proteins

(2016) Naomi Courtemanche et al.   NATURE CELL BIOLOGY

Arp2/3 Complex and Cofilin Modulate Binding of Tropomyosin to Branched Actin Networks

(2015) Jennifer Y. Hsiao et al.   CURRENT BIOLOGY

Profilin-1 Serves as a Gatekeeper for Actin Assembly by Arp2/3-Dependent and -Independent Pathways

(2015) Jeremy D. Rotty et al.   DEVELOPMENTAL CELL

Profilin Regulates F-Actin Network Homeostasis by Favoring Formin over Arp2/3 Complex

(2015) Cristian Suarez et al.   DEVELOPMENTAL CELL

The F-BAR Cdc15 promotes contractile ring formation through the direct recruitment of the formin Cdc12

(2015) Alaina H. Willet et al.   JOURNAL OF CELL BIOLOGY

Tropomyosin - master regulator of actin filament function in the cytoskeleton

(2015) P. W. Gunning et al.   JOURNAL OF CELL SCIENCE

Coronin Enhances Actin Filament Severing by Recruiting Cofilin to Filament Sides and Altering F-Actin Conformation

(2015) Mouna A. Mikati et al.   JOURNAL OF MOLECULAR BIOLOGY

Cordon bleu promotes the assembly of brush border microvilli

(2015) Nathan E. Grega-Larson et al.   MOLECULAR BIOLOGY OF THE CELL

A quantitative imaging-based screen reveals the exocyst as a network hub connecting endocytosis and exocytosis

(2015) Mini Jose et al.   MOLECULAR BIOLOGY OF THE CELL

A mechanism of leading-edge protrusion in the absence of Arp2/3 complex

(2015) Praveen Suraneni et al.   MOLECULAR BIOLOGY OF THE CELL

Arp2/3 complex inhibition radically alters lamellipodial actin architecture, suspended cell shape, and the cell spreading process

(2015) John H. Henson et al.   MOLECULAR BIOLOGY OF THE CELL

Cell type–dependent mechanisms for formin-mediated assembly of filopodia

(2015) Lorna E. Young et al.   MOLECULAR BIOLOGY OF THE CELL

High-speed depolymerization at actin filament ends jointly catalysed by Twinfilin and Srv2/CAP

(2015) Adam B. Johnston et al.   NATURE CELL BIOLOGY

Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarization

(2015) Alexis J. Lomakin et al.   NATURE CELL BIOLOGY

A resilient formin-derived cortical actin meshwork in the rear drives actomyosin-based motility in 2D confinement

(2015) Nagendran Ramalingam et al.   Nature Communications

CPI motif interaction is necessary for capping protein function in cells

(2015) Marc Edwards et al.   Nature Communications

Single-molecule visualization of a formin-capping protein ‘decision complex’ at the actin filament barbed end

(2015) Jeffrey P. Bombardier et al.   Nature Communications

Formin and capping protein together embrace the actin filament in a ménage à trois

(2015) Shashank Shekhar et al.   Nature Communications

Single-molecule imaging of a three-component ordered actin disassembly mechanism

(2015) Silvia Jansen et al.   Nature Communications

Two Functionally Distinct Sources of Actin Monomers Supply the Leading Edge of Lamellipodia

(2015) Eric A. Vitriol et al.   Cell Reports

Formins Determine the Functional Properties of Actin Filaments in Yeast

(2014) Matthew Johnson et al.   CURRENT BIOLOGY

Homeostatic Actin Cytoskeleton Networks Are Regulated by Assembly Factor Competition for Monomers

(2014) Thomas A. Burke et al.   CURRENT BIOLOGY

Synergies between Aip1p and capping protein subunits (Acp1p and Acp2p) in clathrin-mediated endocytosis and cell polarization in fission yeast

(2014) Julien Berro et al.   MOLECULAR BIOLOGY OF THE CELL

Capping protein is essential for cell migration in vivo and for filopodial morphology and dynamics

(2014) Shamim A. Sinnar et al.   MOLECULAR BIOLOGY OF THE CELL

New single-molecule speckle microscopy reveals modification of the retrograde actin flow by focal adhesions at nanometer scales

(2014) Sawako Yamashiro et al.   MOLECULAR BIOLOGY OF THE CELL

Capping protein regulators fine-tune actin assembly dynamics

(2014) Marc Edwards et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Actin Dynamics, Architecture, and Mechanics in Cell Motility

(2014) Laurent Blanchoin et al.   PHYSIOLOGICAL REVIEWS

Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with Fascin

(2014) J. D. Winkelman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arp2/3 complex ATP hydrolysis promotes lamellipodial actin network disassembly but is dispensable for assembly

(2013) Elena Ingerman et al.   JOURNAL OF CELL BIOLOGY

Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin

(2013) Stefan A. Koestler et al.   MOLECULAR BIOLOGY OF THE CELL

F- and G-actin homeostasis regulates mechanosensitive actin nucleation by formins

(2013) Chiharu Higashida et al.   NATURE CELL BIOLOGY

Rickettsia Sca2 has evolved formin-like activity through a different molecular mechanism

(2013) Y. Madasu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Remodeling of Actin Cytoskeleton Architecture by Profilin Isoforms Leads to Distinct Effects on Cell Migration and Invasion

(2012) Ghassan Mouneimne et al.   CANCER CELL

Arp2/3 Is Critical for Lamellipodia and Response to Extracellular Matrix Cues but Is Dispensable for Chemotaxis

(2012) Congying Wu et al.   CELL

Organelle Growth Control through Limiting Pools of Cytoplasmic Components

(2012) Nathan W. Goehring et al.   CURRENT BIOLOGY

Arp2/3 complex–dependent actin networks constrain myosin II function in driving retrograde actin flow

(2012) Qing Yang et al.   JOURNAL OF CELL BIOLOGY

The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration

(2012) Praveen Suraneni et al.   JOURNAL OF CELL BIOLOGY

Srv2/cyclase-associated protein forms hexameric shurikens that directly catalyze actin filament severing by cofilin

(2012) Faisal Chaudhry et al.   MOLECULAR BIOLOGY OF THE CELL

Stimulus-dependent phosphorylation of profilin-1 in angiogenesis

(2012) Yi Fan et al.   NATURE CELL BIOLOGY

How Cells Know the Size of Their Organelles

(2012) Y.-H. M. Chan et al.   SCIENCE

Characterization of Dip1p Reveals a Switch in Arp2/3-Dependent Actin Assembly for Fission Yeast Endocytosis

(2011) Roshni Basu et al.   CURRENT BIOLOGY

Actin filament severing by cofilin is more important for assembly than constriction of the cytokinetic contractile ring

(2011) Qian Chen et al.   JOURNAL OF CELL BIOLOGY

Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension

(2011) Tai Kiuchi et al.   JOURNAL OF CELL BIOLOGY

VASP is a processive actin polymerase that requires monomeric actin for barbed end association

(2010) Scott D. Hansen et al.   JOURNAL OF CELL BIOLOGY

Quantitative Analysis of the Mechanism of Endocytic Actin Patch Assembly and Disassembly in Fission Yeast

(2010) Vladimir Sirotkin et al.   MOLECULAR BIOLOGY OF THE CELL

Rickettsia Sca2 is a bacterial formin-like mediator of actin-based motility

(2010) Cat M. Haglund et al.   NATURE CELL BIOLOGY

A nucleator arms race: cellular control of actin assembly

(2010) Kenneth G. Campellone et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ADF/Cofilin: a functional node in cell biology

(2010) Barbara W. Bernstein et al.   TRENDS IN CELL BIOLOGY

Three's company: the fission yeast actin cytoskeleton

(2010) David R. Kovar et al.   TRENDS IN CELL BIOLOGY

Direct Observation of the Uncapping of Capping Protein-capped Actin Filaments by CARMIL Homology Domain 3

(2009) Ikuko Fujiwara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pob1 Participates in the Cdc42 Regulation of Fission Yeast Actin Cytoskeleton

(2009) Sergio A. Rincón et al.   MOLECULAR BIOLOGY OF THE CELL

A genetically encoded photoactivatable Rac controls the motility of living cells

(2009) Yi I. Wu et al.   NATURE

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Capping Protein Increases the Rate of Actin-Based Motility by Promoting Filament Nucleation by the Arp2/3 Complex

(2008) Orkun Akin et al.   CELL

The Cytokinesis Formins from the Nematode Worm and Fission Yeast Differentially Mediate Actin Filament Assembly

(2008) Erin M. Neidt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Formin Differentially Utilizes Profilin Isoforms to Rapidly Assemble Actin Filaments

(2008) Erin M. Neidt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ena/VASP Proteins Capture Actin Filament Barbed Ends

(2008) Lejla Pasic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells

(2008) Corina Sarmiento et al.   JOURNAL OF CELL BIOLOGY

G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers

(2008) C. Higashida et al.   JOURNAL OF CELL SCIENCE

Cofilin Increases the Bending Flexibility of Actin Filaments: Implications for Severing and Cell Mechanics

(2008) Brannon R. McCullough et al.   JOURNAL OF MOLECULAR BIOLOGY

Analysis of Unregulated Formin Activity Reveals How Yeast Can Balance F-Actin Assembly between Different Microfilament-based Organizations

(2008) Lina Gao et al.   MOLECULAR BIOLOGY OF THE CELL

mDia2 Induces the Actin Scaffold for the Contractile Ring and Stabilizes Its Position during Cytokinesis in NIH 3T3 Cells

(2008) Sadanori Watanabe et al.   MOLECULAR BIOLOGY OF THE CELL

Arp2 depletion inhibits sheet-like protrusions but not linear protrusions of fibroblasts and lymphocytes

(2008) Susan M. Nicholson-Dykstra et al.   CELL MOTILITY AND THE CYTOSKELETON