Article
Multidisciplinary Sciences
Nga T. Ho, Marc Siggel, Karen Camacho, Ramachandra M. Bhaskara, Jacqueline M. Hicks, Yun-Chiao Yao, Yuliang Zhang, Jurgen Kofinger, Gerhard Hummer, Aleksandr Noy
Summary: Liposomes with carbon nanotube porins (CNTPs) on their membranes have been found to be efficient vehicles for direct cytoplasmic drug delivery, enhancing the killing effect of anticancer drugs on cancer cells. This research opens up new possibilities for designing more efficient drug delivery carriers.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Chemistry, Physical
Yun-Chiao Yao, Zhongwu Li, Alice J. Gillen, Shari Yosinski, Mark A. Reed, Aleksandr Noy
Summary: Carbon nanotube porins demonstrate excellent biocompatibility and unique water and ion transport properties. Gating transport with external voltage increases control over ion flow and selectivity. The optimal gated CNTP device consists of a semiconducting CNTP inserted into a small membrane patch containing an internally conductive layer.
JOURNAL OF CHEMICAL PHYSICS
(2021)
Article
Chemistry, Multidisciplinary
Jacqueline M. Hicks, Yun-Chico Yao, Sydney Barber, Nigel Neate, Julie A. Watts, Aleksandr Noy, Frankie J. Rawson
Summary: Cells modulate their homeostasis through the control of redox reactions via transmembrane electron transport systems, with the focus on utilizing carbon nanotube porins as bipolar nanoelectrodes for wireless control of membrane electron transfer.
Article
Chemistry, Physical
Namho Kim, Ji Hye Lee, Yeonho Song, Jeong-Hyung Lee, George C. C. Schatz, Hyonseok Hwang
Summary: The effect of protonation state of glutamic acid on its translocation through cyclic peptide nanotubes (CPNs) was studied using molecular dynamics simulations. The study found that the protonation state of glutamic acid significantly influenced its transport through CPNs, as determined by the permeability coefficients. The potential of mean force calculations showed that the protonation state resulted in different free energy barriers, while the position-dependent diffusion coefficient profiles showed similar frictional behaviors.
JOURNAL OF PHYSICAL CHEMISTRY B
(2023)
Article
Chemistry, Medicinal
Barbara Mavroidi, Archontia Kaminari, Elias Sakellis, Zili Sideratou, Dimitris Tsiourvas
Summary: This study investigated the effect of carbon dots on a model cell membrane. The results showed that carbon dots interact with liposomes, affecting the structure and thermodynamic properties of the bilayer. Furthermore, carbon dots increased the membrane's permeability to the anticancer drug doxorubicin.
Article
Cell Biology
Karis Amata Zecchi, Thomas Heimburg
Summary: Recent evidence suggests that lipid bilayers exhibit conductive properties but are commonly considered inert insulators. Under voltage-clamp conditions, lipid bilayers display current traces with discrete conduction-steps and outward rectification. The non-linear conduction in lipid membranes at different depths indicates voltage-gated and mechanosensitive channels.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Review
Pharmacology & Pharmacy
Mathias Winterhalter
Summary: The challenge lies not in developing selective inhibitors for novel Gram-negative targets, but rather in improving the permeability of antibiotics to reach the lethal target within Gram-negative bacteria. Current research focuses on quantifying the flux of a larger list of compounds at a cellular or single channel level, with the aim of creating a larger dataset to enhance the understanding and effectiveness of antibiotics.
EXPERT OPINION ON DRUG DELIVERY
(2021)
Article
Chemistry, Physical
Sidi Zhao, Alice J. Gillen, Yuhao Li, Aleksandr Noy
Summary: CNTs with transport properties identical to lipid-assisted procedure can be synthesized by sonochemical cutting of long CNT feedstocks in the presence of different surfactants, opening up a wide variety of synthetic routes for CNTP production.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Afang Zhao, Na Zhang, Qiang Li, Lianwen Zhou, Huining Deng, Zhenghua Li, Yi Wang, Enguang Lv, Zhen Li, Mei Qiao, Jihua Wang
Summary: In this study, high-performance nanocomposite reverse osmosis membranes were fabricated by synthesizing functionalized carbon nanotubes and embedding silver nanoparticles. The membrane exhibited improved water permeability and NaCl rejection, as well as excellent fouling resistance to model foulants. The long-term performance stability of the membrane was attributed to the compatibility between carbon nanotubes and the polyamide matrix.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Article
Engineering, Environmental
Zeyong Yan, Ning Li, Qing Chang, Chaorui Xue, Jinlong Yang, Shengliang Hu
Summary: The electric generation performance of traditional polyelectrolyte membrane is improved by introducing the suspension of carbon dots prepared by selective oxidation etching of coal pitch into the aqueous solution of polyvinyl alcohol and poly(4-styrensulfonic acid). The hybrid membrane shows better power generation performance, higher mechanical properties, and a faster directional transport pathway for protons. The excess hydrophilic groups provided by the carbon dots' suspension facilitate water adsorption and the formation of a higher proton concentration gradient. This work offers a facile and economic method for highly efficient moisture-enabled electric generation.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Seonghyun Park, Byungseok Seo, Dongjoon Shin, Seunghoon Chae, Hyunjoon Cho, Sangtae Kim, Wonjoon Choi
Summary: A facile synthesis method is developed to prepare a composite of carbon nanotube and iron oxide. The composite electrode exhibits excellent initial specific capacity and rate capability, and maintains a high capacity after 500 charge-discharge cycles. Morphological and electrochemical characterization reveals the presence of nanoparticles encapsulated within the carbon nanotube network, leading to a hybrid capacity mechanism of redox conversion and pseudocapacitance. This simple synthesis method offers a new approach for the fabrication of low-cost composite electrodes with high performance.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Physical
Romina HMTShirazi, Toraj Mohammadi, Amir Atabak Asadi
Summary: Amino group grafted halloysite nanotubes were used to enhance the adsorption capacity of chitosan/polyvinyl alcohol nanofibers for Cd(II) and Pb(II). By characterizing the compositional changes, morphology, and optimizing adsorption parameters, stable affinity membranes with promising heavy metal ions removal capabilities were obtained.
APPLIED CLAY SCIENCE
(2022)
Article
Construction & Building Technology
Weiqiang Chen, Yanming Liu, Jiangyu Wu, Shuaijie Lu, Guansheng Han, Xingchen Wei, Yuan Gao
Summary: Using amino-functionalised functional groups to coat carbon nanotubes (CNTs) on the surface of fly ash (FA) particles can assist dispersion, prepare cost-effective, low-carbon emission, energy consumption-saving, and high-performance cementitious slurry, improving the compressive and tensile strength as well as workability of cement-based materials.
CONSTRUCTION AND BUILDING MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Zhen Yao, Nikolaus Meyerbroeker, Yubo Qi, Julian Cremer, Michael Westphal, Dario Anselmetti, Yang Yang, Armin Goelzhaeuser
Summary: A scalable synthesis method for carbon nanomembranes (CNMs) has been developed using self-assembled monolayers and electron irradiation. The CNMs, created from poly(4-vinylbiphenyl) (PVBP) spin-coated on SiO(2)/Si wafers, exhibit a high water flux, precise ion selectivity, and high porosity. The method provides a feasible route for large-scale fabrication of CNMs for various applications.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Analytical
Nihal Deligonul, Ilyas Yildiz, Sema Bilgin, Isa Gokce, Omer Isildak
Summary: Developing a selective sensor for a target metal type is challenging. In this study, a novel polymeric membrane electrode (PME) was developed using Green Fluorescent Protein (GFP) as an ionophore for the determination of bismuth ions. The PME exhibited high sensitivity and Nernstian behavior.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Zhongwu Li, Yuhao Li, Yun-Chiao Yao, Fikret Aydin, Cheng Zhan, Yunfei Chen, Menachem Elimelech, Tuan Anh Pham, Aleksandr Noy
Article
Multidisciplinary Sciences
Bedanga Sapkota, Wentao Liang, Armin VahidMohammadi, Rohit Karnik, Aleksandr Noy, Meni Wanunu
NATURE COMMUNICATIONS
(2020)
Article
Nanoscience & Nanotechnology
Razi Epsztein, Ryan M. DuChanois, Cody L. Ritt, Aleksandr Noy, Menachem Elimelech
NATURE NANOTECHNOLOGY
(2020)
Correction
Multidisciplinary Sciences
Bedanga Sapkota, Wentao Liang, Armin VahidMohammadi, Rohit Karnik, Aleksandr Noy, Meni Wanunu
NATURE COMMUNICATIONS
(2020)
Article
Multidisciplinary Sciences
Kylee Sullivan, Yuliang Zhang, Joseph Lopez, Mary Lowe, Aleksandr Noy
SCIENTIFIC REPORTS
(2020)
Article
Multidisciplinary Sciences
Yuhao Li, Zhongwu Li, Fikret Aydin, Jana Quan, Xi Chen, Yun-Chiao Yao, Cheng Zhan, Yunfei Chen, Tuan Anh Pham, Aleksandr Noy
Article
Nanoscience & Nanotechnology
Xi Chen, Aleksandr Noy
Summary: Bioelectronic devices play a crucial role in medical diagnostics, therapeutics delivery, and chronic symptoms monitoring, but their performance is hindered by surface fouling. Researchers are exploring principles and strategies to prevent fouling and enhance device performance through various antifouling approaches.
Article
Multidisciplinary Sciences
Nga T. Ho, Marc Siggel, Karen Camacho, Ramachandra M. Bhaskara, Jacqueline M. Hicks, Yun-Chiao Yao, Yuliang Zhang, Jurgen Kofinger, Gerhard Hummer, Aleksandr Noy
Summary: Liposomes with carbon nanotube porins (CNTPs) on their membranes have been found to be efficient vehicles for direct cytoplasmic drug delivery, enhancing the killing effect of anticancer drugs on cancer cells. This research opens up new possibilities for designing more efficient drug delivery carriers.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Chemistry, Physical
Yun-Chiao Yao, Zhongwu Li, Alice J. Gillen, Shari Yosinski, Mark A. Reed, Aleksandr Noy
Summary: Carbon nanotube porins demonstrate excellent biocompatibility and unique water and ion transport properties. Gating transport with external voltage increases control over ion flow and selectivity. The optimal gated CNTP device consists of a semiconducting CNTP inserted into a small membrane patch containing an internally conductive layer.
JOURNAL OF CHEMICAL PHYSICS
(2021)
Article
Chemistry, Physical
Joshua A. Hammons, Marcel D. Baer, Tengyue Jian, Jonathan R. Lee, Thomas M. Weiss, James J. De Yoreo, Aleksandr Noy, Chun-Long Chen, Anthony Van Buuren
Summary: This study used in situ X-ray scattering and molecular dynamics simulations to investigate the early stages of assembly of three different peptoids. Results showed that peptoids first aggregated into a less crystalline nascent phase before forming the more crystalline peptoid membrane, with anisotropic aromatic interactions identified as the dominant driving force in the early stages of membrane formation. These insights provide valuable information on how to manipulate peptoid assembly during the early stages of nucleation and growth.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Jacqueline M. Hicks, Yun-Chico Yao, Sydney Barber, Nigel Neate, Julie A. Watts, Aleksandr Noy, Frankie J. Rawson
Summary: Cells modulate their homeostasis through the control of redox reactions via transmembrane electron transport systems, with the focus on utilizing carbon nanotube porins as bipolar nanoelectrodes for wireless control of membrane electron transfer.
Editorial Material
Nanoscience & Nanotechnology
Marco Rolandi, Aleksandr Noy, Sahika Inal, Jonathan Rivnay
Article
Nanoscience & Nanotechnology
Zhongwu Li, Rahul Prasanna Misra, Yuhao Li, Yun-Chiao Yao, Sidi Zhao, Yuliang Zhang, Yunfei Chen, Daniel Blankschtein, Aleksandr Noy
Summary: Experimental measurements and molecular dynamics simulations show that the Nernst-Einstein relation breaks down in narrow carbon nanotube porins. K+ ion diffusion is three orders of magnitude slower in these channels due to the disintegration of water chains and the formation of K+-water clusters. This study reveals two distinct mechanisms for ion diffusion and electromigration, leading to the breakdown of the overall Nernst-Einstein relation.
NATURE NANOTECHNOLOGY
(2023)
Article
Chemistry, Physical
Sidi Zhao, Alice J. Gillen, Yuhao Li, Aleksandr Noy
Summary: CNTs with transport properties identical to lipid-assisted procedure can be synthesized by sonochemical cutting of long CNT feedstocks in the presence of different surfactants, opening up a wide variety of synthetic routes for CNTP production.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Aleksandr Noy, Zhongwu Li, Seth B. Darling
Summary: The rising energy demands in computing require rethinking hardware paradigms for energy efficiency. Neuromorphic computing mimics the brain's principles but faces scalability and power consumption challenges. Computing with ion transport in water through nanochannels emerges as a potentially revolutionary approach with energy-efficient possibilities.
