Optimization of drug combinations using Feedback System Control

Mechanism-Independent Optimization of Combinatorial Nanodiamond and Unmodified Drug Delivery Using a Phenotypically Driven Platform Technology

(2015) Hann Wang et al.   ACS Nano

Rapid optimization of drug combinations for the optimal angiostatic treatment of cancer

(2015) Andrea Weiss et al.   ANGIOGENESIS

A streamlined search technology for identification of synergistic drug combinations

(2015) Andrea Weiss et al.   Scientific Reports

Intratumor heterogeneity alters most effective drugs in designed combinations

(2014) B. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bayesian Active Learning for Drug Combinations

(2013) Mijung Park et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Guiding the osteogenic fate of mouse and human mesenchymal stem cells through feedback system control

(2013) Yoshitomo Honda et al.   Scientific Reports

Modeling To Predict Growth/No Growth Boundaries and Kinetic Behavior of Salmonella on Cutting Board Surfaces

(2012) HYUNJOO YOON et al.   JOURNAL OF FOOD PROTECTION

Mechanism-independent method for predicting response to multidrug combinations in bacteria

(2012) Kevin Wood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of Fractional Factorial Designs in Antiviral Drug Studies

(2012) Xianting Ding et al.   QUALITY AND RELIABILITY ENGINEERING INTERNATIONAL

Enhanced stochastic optimization algorithm for finding effective multi-target therapeutics

(2011) Byung-Jun Yoon   BMC BIOINFORMATICS

Cross-validated stepwise regression for identification of novel non-nucleoside reverse transcriptase inhibitor resistance associated mutations

(2011) Koen Van der Borght et al.   BMC BIOINFORMATICS

Systematic quantitative characterization of cellular responses induced by multiple signals

(2011) Ibrahim Al-Shyoukh et al.   BMC Systems Biology

Control of Kaposi's Sarcoma-Associated Herpesvirus Reactivation Induced by Multiple Signals

(2011) Fuqu Yu et al.   PLoS One

An optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells

(2011) Hideaki Tsutsui et al.   Nature Communications

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Differential Evolution: A Survey of the State-of-the-Art

(2010) Swagatam Das et al.   IEEE TRANSACTIONS ON EVOLUTIONARY COMPUTATION

Synergistic drug combinations tend to improve therapeutically relevant selectivity

(2009) Joseph Lehár et al.   NATURE BIOTECHNOLOGY

Mechanisms of drug combinations: interaction and network perspectives

(2009) Jia Jia et al.   NATURE REVIEWS DRUG DISCOVERY

Chemotherapy, Bevacizumab, and Cetuximab in Metastatic Colorectal Cancer

(2009) Jolien Tol et al.   NEW ENGLAND JOURNAL OF MEDICINE

Systems approaches and algorithms for discovery of combinatorial therapies

(2009) Jacob D. Feala et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Integrative systems control approach for reactivating Kaposi’s sarcoma-associated herpesvirus (KSHV) with combinatory drugs

(2008) Chien-Pin Sun et al.   Integrative Biology

Models from experiments: combinatorial drug perturbations of cancer cells

(2008) Sven Nelander et al.   Molecular Systems Biology

Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm

(2008) Pak Kin Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Search Algorithms as a Framework for the Optimization of Drug Combinations

(2008) Diego Calzolari et al.   PLoS Computational Biology