Review
Chemistry, Multidisciplinary
Akio Yoneyama, Daiko Takamatsu, Thet-Thet Lwin, Shigehito Yamada, Tetsuya Takakuwa, Kazuyuki Hyodo, Keiichi Hirano, Satoshi Takeya
Summary: Crystal-based X-ray interferometry (CXI) detects X-ray phase shifts with the highest sensitivity among the X-ray phase-detecting methods. Phase-contrast X-ray imaging (PCXI) using CXI has the highest density resolution and has been widely applied in various fields. Novel imaging methods have also been developed to take advantage of CXI's high sensitivity, such as visualization of the effective atomic number and the three-dimensional temperature. This article reviews the principles, history, and potential applications of PCXI and CXI systems.
APPLIED SCIENCES-BASEL
(2023)
Article
Optics
Hunwoo Lee, Duhee Jeon, Hyunwoo Lim, Hyosung Cho, Myeongkyu Park, Wonsik Youn
Summary: A method was proposed to effectively remove the Moire artifact by employing a grid angulation technique to improve image quality in Single-grid-based phase-contrast x-ray imaging (SG-PCXI). Experimental verification confirmed the effectiveness of the method, demonstrating a significant improvement in image quality.
Article
Optics
Zhi Qiao, Xianbo Shi, Yudong Yao, Michael J. Wojcik, Luca Rebuffi, Mathew J. Cherukara, Lahsen Assoufid
Summary: By utilizing deep learning, the speckle-based phase-contrast imaging neural network (SPINNet) significantly enhances imaging quality and retrieval speed compared to existing methods. It enables high-resolution and fast data acquisition and processing for various applications.
Article
Multidisciplinary Sciences
Hongchang Wang, Kawal Sawhney
Summary: Researchers have successfully generated omnidirectional differential phase images using X-ray differential phase contrast imaging, providing more information for studying complex samples and enabling simultaneous extraction of omnidirectional dark-field images to study ordered scattering structures.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Multidisciplinary Sciences
Hongchang Wang, Kawal Sawhney
Summary: This article introduces a method for generating omnidirectional differential phase images by scanning a randomly structured modulator, which provides more information than traditional imaging methods and allows the simultaneous extraction of omnidirectional dark-field images for studying strongly ordered scattering structures.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Physics, Applied
L. Brombal, F. Arfelli, F. Brun, F. Longo, N. Poles, L. Rigon
Summary: Accurate simulation tools are important for the design and optimization of x-ray phase-contrast imaging setups. This study presents a practical implementation of x-ray phase-contrast in Geant4 and validates the simulation results against theoretical predictions.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2022)
Article
Physics, Multidisciplinary
Jiecheng Yang, Peiping Zhu, Dong Liang, Hairong Zheng, Yongshuai Ge
Summary: A general theoretical framework is presented to explain the formation of the phase signal in an x-ray microscope integrated with a grating interferometer. This theory can predict key parameters of phase contrast imaging and has been validated through numerical simulations.
Review
Physics, Condensed Matter
Alessandro Olivo
Summary: X-ray phase-contrast imaging (XPCI) gained popularity in the mid-90s due to the capabilities of revealing previously invisible object features. While early XPCI implementations required synchrotron facilities for efficiency, new approaches in the mid-00s allowed for XPCI with conventional x-ray sources. One promising approach is edge-illumination XPCI, which is evolving towards practical applications in contemporary XPCI research.
JOURNAL OF PHYSICS-CONDENSED MATTER
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lorenzo Massimi, Tom Partridge, Alberto Astolfo, Marco Endrizzi, Charlotte K. Hagen, Peter R. T. Munro, David Bate, Alessandro Olivo
Summary: This work presents an analytical model describing the noise in the various contrast channels retrieved in edge illumination as a function of the illumination curve sampling. An optimal sampling scheme leading to minimum noise has been determined for the case where 3 or 5 sampling points are used, which represent two of the most common acquisition schemes. Additionally, the correlation between noise in the different channels and the role of the number of points and exposure time have been investigated.
Article
Engineering, Biomedical
Glafkos Havariyoun, Lorenzo Massimi, Charlotte Hagen, Marco Endrizzi, Alessandro Olivo
Summary: This study investigates the performance of a mask-based system, such as EI-XPCI, in terms of Modulation Transfer Function (MTF), without phase effects. The results show that the non-skipped mask setup provides improved MTF results compared to the inherent MTF of the detector. However, the improvement is limited to specific frequencies dictated by the spatial repetition of the spill-out signal. On the other hand, skipped masks provide further MTF improvements over a larger frequency range.
PHYSICS IN MEDICINE AND BIOLOGY
(2023)
Article
Optics
Xin Liu, Lang Liu, Jianheng Huang, Yaohu Lei, Ji Li
Summary: In this paper, a single grating imaging system is proposed for X-ray phase-contrast imaging. The system uses a single-shot algorithm to retrieve attenuation and phase gradient distribution, achieving time-saving and detail preservation. By using a large-size X-ray detector, the system can be configured for both microscopic and large field-of-view imaging.
Article
Engineering, Mechanical
T. Zhong, Y. Y. Zhang, S. Chen, B. B. Zhang, Y. Tao, S. N. Luo, S. J. Ye, J. Y. Huang
Summary: The study investigates penetration dynamics of carbonate sand using high-speed X-ray phase contrast imaging and finds that increased moisture content results in particle clustering and reduced ejecta, while smaller container size limits lateral movement of particles.
INTERNATIONAL JOURNAL OF IMPACT ENGINEERING
(2021)
Article
Engineering, Biomedical
Jae-Suk Yang, Sun-Young Jeon, Jang-Hwan Choi
Summary: This study proposes an effective method for obtaining phase-contrast X-ray images using instantaneous frequency and noise filtering. The proposed method effectively suppresses noise with Moire patterns and preserves internal anatomical information from the biological sample. Compared to conventional methods, this method achieves better imaging quality and detailed information.
BIOMEDICAL ENGINEERING ONLINE
(2022)
Article
Multidisciplinary Sciences
Matteo Busi, Jiazhou Shen, Michael Bacak, Marie Christine Zdora, Jan Capek, Jacopo Valsecchi, Markus Strobl
Summary: This study introduces a novel multi-directional neutron dark-field imaging approach that utilizes a single absorption grating to simultaneously probe multiple scattering directions. The method successfully resolves the microstructural properties of materials and overcomes limitations of conventional neutron dark-field imaging in assessing complex heterogeneous anisotropic microstructures.
SCIENTIFIC REPORTS
(2023)
Article
Engineering, Biomedical
Ngoc Ton, Una Goncin, Arash Panahifar, Dean Chapman, Sheldon Wiebe, Steven Machtaler
Summary: The study aimed to evaluate the feasibility of ultrasound microbubbles as a contrast agent for X-ray phase contrast imaging. Results suggest that lipid-MBs larger than 4 µm may be candidates for PCI, and a concentration of 5 x 10(6) MBs/ml could be the lowest suitable concentration for generating visible phase contrast in vivo.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2021)
Article
Physics, Multidisciplinary
D. Sarenac, D. A. Pushin, M. G. Huber, D. S. Hussey, H. Miao, M. Arif, D. G. Cory, A. D. Cronin, B. Heacock, D. L. Jacobson, J. M. LaManna, H. Wen
PHYSICAL REVIEW LETTERS
(2018)
Article
Urology & Nephrology
Bradley D. Figler, Andrew Gomella, Logan Hubbard
Article
Multidisciplinary Sciences
Mona Mirzaeimoghri, Alejandro Morales Martinez, Alireza Panna, Eric E. Bennett, Bertrand M. Lucotte, Don L. DeVoe, Han Wen
Article
Multidisciplinary Sciences
Han Wen, Alejandro Morales Martinez, Houxun Miao, Thomas C. Larsen, Catherine P. Nguyen, Eric E. Bennett, Kellan P. Moorse, Zu-Xi Yu, Alan T. Remaley, Manfred Boehm, Ahmed M. Gharib
SCIENTIFIC REPORTS
(2018)
Article
Cell Biology
Alexander S. Zhovmer, Erdem D. Tabdanov, Houxun Miao, Han Wen, Jinqiu Chen, Xiaoling Luo, Xuefei Ma, Paolo P. Provenzano, Robert S. Adelstein
MOLECULAR BIOLOGY OF THE CELL
(2019)
Article
Nanoscience & Nanotechnology
B. Heacock, D. Sarenac, D. G. Cory, M. G. Huber, D. S. Hussey, C. Kapahi, H. Miao, H. Wen, D. A. Pushin
Article
Chemistry, Multidisciplinary
B. Heacock, D. Sarenac, D. G. Cory, M. G. Huber, J. P. W. MacLean, H. Miao, H. Wen, D. A. Pushin
Article
Imaging Science & Photographic Technology
Piroz Bahar, David Nguyen, Muyang Wang, Dumitru Mazilu, Eric E. Bennett, Han Wen
Summary: This paper presents a method for online calibration in a linear tomosynthesis scanner. By attaching a layer of randomly dispersed micro glass beads or calcium particles to the bottom of the sample stage, the trajectory of the scanning stage can be determined for each scan, avoiding blurring and artifacts in the images caused by errors in geometric information.
JOURNAL OF IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Thomas C. Larsen, Eric E. Bennett, Dumitru Mazilu, Marcus Y. Chen, Han Wen
Meeting Abstract
Biochemistry & Molecular Biology
Han Wen, Houxun Miao, Thomas Larsen, Alejandro Morales-Martinez, Zu-Xi Yu, Eric Bennett, Manfred Boehm, Alan T. Remaley, Ahmed M. Gharib
Proceedings Paper
Materials Science, Multidisciplinary
Houxun Miao, Mona Mirzaeimoghri, Lei Chen, Han Wen
2017 INTERNATIONAL CONFERENCE ON OPTICAL MEMS AND NANOPHOTONICS (OMN)
(2017)
Article
Radiology, Nuclear Medicine & Medical Imaging
Alex George, Peter Y. Chen, Alejandro Morales-Martinez, Alireza Panna, Andrew A. Gomella, Eric E. Bennett, Han Wen
JOURNAL OF MEDICAL IMAGING
(2017)
Article
Optics
D. A. Pushin, D. Sarenac, D. S. Hussey, H. Miao, M. Arif, D. G. Cory, M. G. Huber, D. L. Jacobson, J. M. LaManna, J. D. Parker, T. Shinohara, W. Ueno, H. Wen