Late stages of T cell maturation in the thymus involve NF-κB and tonic type I interferon signaling

Development of thymic Foxp3+ regulatory T cells: TGF-β matters

(2015) WanJun Chen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity

(2015) Anetta Härtlova et al.   IMMUNITY

IFN-α/β Receptor Signaling Promotes Regulatory T Cell Development and Function under Stress Conditions

(2015) Amina Metidji et al.   JOURNAL OF IMMUNOLOGY

T Cell Adolescence: Maturation Events Beyond Positive Selection

(2015) Kristin A. Hogquist et al.   JOURNAL OF IMMUNOLOGY

DNA-Damage-Induced Type I Interferon Promotes Senescence and Inhibits Stem Cell Function

(2015) Qiujing Yu et al.   Cell Reports

Overlapping and Asymmetric Functions of TCR Signaling during Thymic Selection of CD4 and CD8 Lineages

(2014) C. Sinclair et al.   JOURNAL OF IMMUNOLOGY

Differential Requirement for CCR4 and CCR7 during the Development of Innate and Adaptive   T Cells in the Adult Thymus

(2014) J. E. Cowan et al.   JOURNAL OF IMMUNOLOGY

Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells

(2014) Shawn A Mahmud et al.   NATURE IMMUNOLOGY

Double-Stranded RNA of Intestinal Commensal but Not Pathogenic Bacteria Triggers Production of Protective Interferon-β

(2013) Tadaomi Kawashima et al.   IMMUNITY

The thymic medulla is required for Foxp3+regulatory but not conventional CD4+thymocyte development

(2013) Jennifer E. Cowan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IRF7-Dependent IFN-  Production in Response to RANKL Promotes Medullary Thymic Epithelial Cell Development

(2013) D. C. Otero et al.   JOURNAL OF IMMUNOLOGY

The transcriptional landscape of αβ T cell differentiation

(2013) Michael Mingueneau et al.   NATURE IMMUNOLOGY

Homeostatic Properties and Phenotypic Maturation of Murine CD4+ Pre-Thymic Emigrants in the Thymus

(2013) Jie Dong et al.   PLoS One

Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity

(2012) Michael C. Abt et al.   IMMUNITY

Constitutive Type I Interferon Modulates Homeostatic Balance through Tonic Signaling

(2012) Daniel J. Gough et al.   IMMUNITY

Priming of Natural Killer Cells by Nonmucosal Mononuclear Phagocytes Requires Instructive Signals from Commensal Microbiota

(2012) Stephanie C. Ganal et al.   IMMUNITY

The regulation of TNF signalling: what a tangled web we weave

(2011) John Silke   CURRENT OPINION IN IMMUNOLOGY

Decision checkpoints in the thymus

(2010) Andrea C Carpenter et al.   NATURE IMMUNOLOGY

Maturation-Dependent Licensing of Naive T Cells for Rapid TNF Production

(2010) Bhavana Priyadharshini et al.   PLoS One

Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1

(2010) Daniel J. Gough et al.   PLOS BIOLOGY

KLF2 Transcription-Factor Deficiency in T Cells Results in Unrestrained Cytokine Production and Upregulation of Bystander Chemokine Receptors

(2009) Michael A. Weinreich et al.   IMMUNITY

Novel Reporter Mouse Reveals Constitutive and Inflammatory Expression of IFN-  In Vivo

(2009) S. Lienenklaus et al.   JOURNAL OF IMMUNOLOGY

CARMA1 Controls an Early Checkpoint in the Thymic Development of FoxP3+ Regulatory T Cells

(2009) L. L. Molinero et al.   JOURNAL OF IMMUNOLOGY

Commitment to the Regulatory T Cell Lineage Requires CARMA1 in the Thymus but Not in the Periphery

(2009) Michael J Barnes et al.   PLOS BIOLOGY

Differential Role of the Transcription Factor NF-κB in Selection and Survival of CD4+ and CD8+ Thymocytes

(2008) Eijiro Jimi et al.   IMMUNITY

CD4-CD8 Lineage Commitment Is Regulated by a Silencer Element at the ThPOK Transcription-Factor Locus

(2008) Xi He et al.   IMMUNITY

Repression of the Transcription Factor Th-POK by Runx Complexes in Cytotoxic T Cell Development

(2008) R. Setoguchi et al.   SCIENCE