TFH cells progressively differentiate to regulate the germinal center response

Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation

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IL-21 and IL-4 Collaborate To Shape T-Dependent Antibody Responses

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IL-4–Secreting Secondary T Follicular Helper (Tfh) Cells Arise from Memory T Cells, Not Persisting Tfh Cells, through a B Cell–Dependent Mechanism

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CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow

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T–B-cell entanglement and ICOSL-driven feed-forward regulation of germinal centre reaction

(2014) Dan Liu et al.   NATURE

Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development

(2014) Xindong Liu et al.   NATURE

Clonal selection in the germinal centre by regulated proliferation and hypermutation

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Dynamic signaling by T follicular helper cells during germinal center B cell selection

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Germinal Center Centroblasts Transition to a Centrocyte Phenotype According to a Timed Program and Depend on the Dark Zone for Effective Selection

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CD301b+ Dermal Dendritic Cells Drive T Helper 2 Cell-Mediated Immunity

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Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility

(2013) Heping Xu et al.   NATURE

The development and fate of follicular helper T cells defined by an IL-21 reporter mouse

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Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

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Opposing Signals from the Bcl6 Transcription Factor and the Interleukin-2 Receptor Generate T Helper 1 Central and Effector Memory Cells

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The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells

(2011) Wataru Ise et al.   NATURE IMMUNOLOGY

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

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IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism

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Constitutive CD40L Expression on B Cells Prematurely Terminates Germinal Center Response and Leads to Augmented Plasma Cell Production in T Cell Areas

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Germinal Center T Follicular Helper Cell IL-4 Production Is Dependent on Signaling Lymphocytic Activation Molecule Receptor (CD150)

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In Vivo Regulation of Bcl6 and T Follicular Helper Cell Development

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T follicular helper cells differentiate from Th2 cells in response to helminth antigens

(2009) Arielle Glatman Zaretsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-4–producing CD4+T cells in reactive lymph nodes during helminth infection are T follicular helper cells

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Cytokine-secreting follicular T cells shape the antibody repertoire

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T Follicular Helper (TFH) Cells in Normal and Dysregulated Immune Responses

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Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities

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Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-κB pathway and promotes lymphomagenesis

(2008) Cornelia Hömig-Hölzel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity

(2008) Jared M. Odegard et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

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