Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance

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Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

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A mutational signature in gastric cancer suggests therapeutic strategies

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ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors

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A Simple Model-Based Approach to Inferring and Visualizing Cancer Mutation Signatures

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Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial

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Comprehensive molecular characterization of gastric adenocarcinoma

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Comprehensive molecular profiling of lung adenocarcinoma

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Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

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Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis

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Copynumber: Efficient algorithms for single- and multi-track copy number segmentation

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Criteria for Inference of Chromothripsis in Cancer Genomes

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Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity

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Common Fragile Site Profiling in Epithelial and Erythroid Cells Reveals that Most Recurrent Cancer Deletions Lie in Fragile Sites Hosting Large Genes

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Strelka: accurate somatic small-variant calling from sequenced tumor–normal sample pairs

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Structural analysis of the genome of breast cancer cell line ZR-75-30 identifies twelve expressed fusion genes

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MK-1775, a Novel Wee1 Kinase Inhibitor, Radiosensitizes p53-Defective Human Tumor Cells

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Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial

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Long-Term Results of a Randomized Trial of Surgery With or Without Preoperative Chemotherapy in Esophageal Cancer

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Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

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