CREBRF variant increases obesity risk and protects against diabetes in Samoans

Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants

(2016)   LANCET

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants

(2016)   LANCET

A thrifty variant in CREBRF strongly influences body mass index in Samoans

(2016) Ryan L Minster et al.   NATURE GENETICS

ABCC8R1420H Loss-of-Function Variant in a Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of Type 2 Diabetes

(2015) Leslie J. Baier et al.   DIABETES

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

(2015) Thomas W. Winkler et al.   PLoS Genetics

Prevalence of adiposity and associated cardiometabolic risk factors in the samoan genome-wide association study

(2014) Nicola L. Hawley et al.   AMERICAN JOURNAL OF HUMAN BIOLOGY

Genetic Evidence for a Normal-Weight "Metabolically Obese" Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes

(2014) H. Yaghootkar et al.   DIABETES

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

(2014) Ida Moltke et al.   NATURE

Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits

(2013) Unnur Styrkarsdottir et al.   NATURE

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

(2011) Tuomas O Kilpeläinen et al.   NATURE GENETICS

Thrifty genes for obesity, an attractive but flawed idea and an alternative perspective: the ‘drifty gene’ hypothesis

(2008) J R Speakman   INTERNATIONAL JOURNAL OF OBESITY