Review
Geriatrics & Gerontology
Katrine Bukan, Toby Pearce-Slade, Mads Eiberg, Marco Tinelli, Dafna Yahav, Jose Tuells, Olivier Epaulard, Jon G. Holler, Casper Roed, Christian Soborg, Jens-Ulrik Staehr Jensen, Zitta Barrella Harboe
Summary: During the COVID-19 pandemic, there was a decrease in the exclusion of older adults from vaccine trials, but no significant change in the inclusion of immunocompromised individuals.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Immunology
Mehmet Akif Sezerol, Selin Davun
Summary: This study surveyed 2383 older adults aged 65-75 who had not received the third dose of the COVID-19 vaccine. The study found that vaccination willingness was associated with factors such as vaccination beliefs, gender, age, education level, and forgetfulness. The results show the importance of informing older adults about the risks of not being vaccinated and the potential benefits of additional doses in reducing mortality rates.
Review
Geriatrics & Gerontology
Birgit Weinberger
Summary: Maintaining good health in old age is crucial for alleviating societal, economic, and healthcare challenges caused by aging populations. Preventing infections through vaccination is an important measure to ensure healthy aging and preserve quality of life for older adults. Ongoing research is focused on improving vaccines, developing universal vaccines, and increasing awareness for life-long vaccination to protect the vulnerable older age group.
Article
Public, Environmental & Occupational Health
Lu Wei, Wu Zeng, Yangyang Huang, Guoxin Ye, Ying Chen, Ling Yang, Yuyang Cai
Summary: This study aimed to examine the coverage of COVID-19 vaccination and its cognitive determinants among older adults in China. A survey was conducted among 725 Chinese older adults, and the results showed that the vaccination rate was 78.3%. The vaccinated group had better internal risk perception, knowledge of COVID-19 vaccines, and a more positive attitude toward their efficacy and safety compared to the unvaccinated group.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Virology
Rabia Bag Soytas, Mahir Cengiz, Mehmet S. Islamoglu, Betul Borku Uysal, Serap Yavuzer, Hakan Yavuzer
Summary: The study compared the antibody levels of patients aged 60 and older who received different COVID-19 vaccine regimens, showing that the immunity formed after two doses of CoronaVac plus one dose of Pfizer-BioNTech was significantly higher in older adults than after three doses of CoronaVac.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Article
Immunology
Yi Xu, Min Ting Alicia See, Fazila Aloweni, Chun Hui Fion Koh, Cheng Gaik Irene Tan, Xiao Hui Xin, Wee Hoe Gan, Lian Leng Low, Su Fee Lim
Summary: The study aimed to explore the factors influencing vaccine uptake and the impact of COVID-19 on vaccine uptake among community-dwelling older adults in Singapore. Living arrangement was found to be a significant contributing factor, with those living alone more likely to be vaccinated. Key enablers for vaccine uptake included avoidance of infection and transmission, as well as healthcare professionals' advice, while barriers included concerns about side effects, vaccine effectiveness, and lack of information. Greater public health efforts and information provision by healthcare professionals are needed to encourage vaccine uptake, especially during COVID-19.
Article
Psychology, Multidisciplinary
Yuan Cao, Judy Yuen-man Siu, Kup-Sze Choi, Nick Cho-lik Ho, Kai Chun Wong, David H. K. Shum
Summary: This study investigated the relationship between individuals' knowledge, attitude, and daily behavioral practices related to COVID-19 (KAP) and their susceptibility to PTSD. The results showed that poor knowledge, negative attitude, and lack of preventative practices were associated with higher vulnerability to PTSD. Positive attitude and good compliance with preventative practices predicted vaccine acceptance and willingness to participate in voluntary testing. Good knowledge of COVID-19 predicted engagement in testing but had little association with vaccine acceptance.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Medicine, General & Internal
Mariam Davtyan, Toinette Frederick, Jeff Taylor, Christopher Christensen, Brandon J. Brown, Annie L. Nguyen
Summary: In the Coachella Valley, among HIV-positive individuals aged 50 and older, 75% expressed acceptance of the COVID-19 vaccine. Those with lower vaccine acceptability rates were typically younger, experienced higher levels of HIV-related stigma and depression, and had lower levels of personal mastery.
Article
Immunology
Maria Gabriela Matta, Laura Pulido, Juan Jose Herrera-Paz, Jose M. Picco, Sebastian Wolff, Gary Tse, Sebastian Garcia -Zamora
Summary: The study aimed to describe the vaccination rates in volunteers from three regions of Argentina during the COVID-19 pandemic. A survey of 3853 adults in 2020 found that the influenza vaccination rate was 37.7%, pneumococcal vaccination rate was 24.7%, and both vaccines were received by 17.8% of the participants. The study showed suboptimal vaccination rates among high-risk patients in Argentina and highlighted the potential neglect of immunizations during the COVID-19 pandemic.
Article
Public, Environmental & Occupational Health
Aminath S. Moosa, Yi M. S. Wee, Meng H. Jaw, Qifan F. Tan, Wan L. D. Tse, Chui Y. Loke, Guan L. A. Ee, Chee C. D. Ng, Wai K. Aau, Yi L. E. Koh, Ngiap C. Tan
Summary: This study reports an outreach program in Singapore that aimed to increase the COVID-19 vaccination uptake among older adults through phone conversations addressing vaccine hesitancy. The program successfully increased the vaccination rate from 84.6% to 96.3% among the targeted population.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Immunology
Simran Kumar, Zayna Shah, Sara Garfield
Summary: This review identifies the causes of vaccine hesitancy related to the COVID-19 and influenza vaccines. The findings suggest that concerns over safety, lack of trust, lack of need for vaccination, and cultural reasons contribute to vaccine hesitancy. Scientific knowledge and the size of clinical trials can reduce vaccine hesitancy, but pharmaceutical companies are not trusted sources of information.
Article
Immunology
Min Joo Choi, Gyeongseon Shin, Daewon Kang, Jae-Ok Lim, Yun-Kyung Kim, Won Suk Choi, Jae-Won Yun, Ji Yun Noh, Joon Young Song, Woo Joo Kim, Sang-Eun Choi, Hee Jin Cheong
Summary: This study evaluated the cost-effectiveness of different influenza vaccines under the Korean National Immunization Program for different age groups. The results showed that the high-dose quadrivalent vaccine (HD-QIV) was the most cost-effective choice for adults aged 65 years or older. For other high-risk age groups, the introduction of influenza vaccine programs, whether using the traditional trivalent vaccine (TIV) or quadrivalent vaccine (QIV), was cost-effective.
Article
Immunology
Constantina Boikos, Mahrukh Imran, Van Hung Nguyen, Thierry Ducruet, Gregg C. Sylvester, James A. Mansi
Summary: MF59(R)-adjuvanted trivalent inactivated influenza vaccine (aIIV3) and high-dose trivalent inactivated influenza vaccine (HD-IIV3) demonstrate enhanced immune response in older adults compared to standard, quadrivalent inactivated influenza vaccines (IIV4). The study shows that aIIV3 is more effective than IIV4 in preventing influenza-related medical encounters in both the 2017-2018 and 2018-2019 seasons, with HD-IIV3 showing comparable effectiveness.
Article
Immunology
Mateusz Cybulski, Zyta Beata Wojszel, Aleksandra Wojszel, Sara Jahel, Paulina Sliwinska, Elzbieta Krajewska-Kulak
Summary: The fear of COVID-19 infection is widespread among older adults in Poland. Information campaigns are crucial in promoting mass vaccination against COVID-19, but success depends on vaccination coverage. This study aimed to assess COVID-19 anxiety severity and vaccine attitudes among older adults. Findings showed that COVID-19 anxiety was moderate, with seniors more likely to have positive vaccine attitudes. efforts should be made to motivate and encourage preventive vaccination in this age group.
Review
Immunology
Yiwen Xie, Xuebin Tian, Xiaodi Zhang, Hangping Yao, Nanping Wu
Summary: Vaccines have been successful in controlling infectious diseases, but influenza and COVID-19 vaccines face challenges due to the variability of the viral proteins. Immune imprinting and repeated vaccinations can negatively influence vaccine effectiveness, and co-administration of multiple vaccines can also interfere with their effectiveness. Future development of COVID-19 vaccines should focus on inducing cross-reactive T-cell responses and naive B-cell responses, while the strategy of co-administering influenza and COVID-19 vaccines needs more careful consideration and further clinical data.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Xinyue Zhang, Yunying Zhu, Shuting Li, Xinxin Ye, Leying Hou, Yating You, Chenyu Wang, Yuhang Wu, Junmeng Zhang, Yinlin Wang, Peige Song, Xi Mao
Summary: Over the last two decades, pulse pressure (PP) and mean arterial pressure (MAP) levels have been increasing significantly in Chinese children and adolescents. Age, sex, economic status, geographic factors, and anthropometric and cardiometabolic factors are positively associated with PP and MAP in the pediatric population.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Primary Health Care
Yating You, Xiaoheng Li, Shiqiang Jiang, Jing Liang, Pei Xie, Xuan Zou, Gang Liu, Xinxin Han
Summary: To promote influenza vaccination coverage, Shenzhen provides free influenza vaccination to residents aged 60 years and above through community health centres. A study was conducted to evaluate the effect of primary care physicians (PCPs) recommendation on influenza vaccination. The results showed that PCP recommendation improved influenza vaccine uptake and knowledge, attitude, and practice levels regarding influenza vaccination among older adults.
Article
Plant Sciences
Tantan Zhang, Xiaoping He, Binglin Chen, Longxin He, Xiangru Tang
Summary: Potassium fertilizer treatments significantly improve rice yield formation, chlorophyll content, dry matter accumulation, total N and K accumulation in aboveground tissues, breaking-resistant strength, and reduce lodging index.
PHYTON-INTERNATIONAL JOURNAL OF EXPERIMENTAL BOTANY
(2021)
