Long-term Effects of IL-6 Receptor Blockade Therapy on Regulatory Lymphocytes and Neutrophils in Neuromyelitis Optica Spectrum Disorder

Exploring steroid tapering in patients with neuromyelitis optica spectrum disorder treated with satralizumab in SAkuraSky: A case series

(2022) Takashi Yamamura et al.   Multiple Sclerosis and Related Disorders

Cell-Free DNA Derived From Neutrophils Triggers Type 1 Interferon Signature in Neuromyelitis Optica Spectrum Disorder

(2022) Hisashi Murata et al.   Neurology-Neuroimmunology & Neuroinflammation

Interleukin-6 mediates neutrophil mobilization from bone marrow in pulmonary hypertension

(2021) Jonathan Florentin et al.   Cellular & Molecular Immunology

Long‐Term Safety and Efficacy of Eculizumab in Aquaporin‐4 IgG‐Positive NMOSD

(2021) Dean M. Wingerchuk et al.   ANNALS OF NEUROLOGY

Blood-brain barrier resealing in neuromyelitis optica occurs independently of astrocyte regeneration

(2021) Anne Winkler et al.   JOURNAL OF CLINICAL INVESTIGATION

Hope for patients with neuromyelitis optica spectrum disorders — from mechanisms to trials

(2021) Sean J. Pittock et al.   Nature Reviews Neurology

Safety and efficacy of satralizumab monotherapy in neuromyelitis optica spectrum disorder: a randomised, double-blind, multicentre, placebo-controlled phase 3 trial

(2020) Anthony Traboulsee et al.   LANCET NEUROLOGY

Safety and efficacy of rituximab in neuromyelitis optica spectrum disorders (RIN-1 study): a multicentre, randomised, double-blind, placebo-controlled trial

(2020) Masayuki Tahara et al.   LANCET NEUROLOGY

Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial

(2019) Bruce A C Cree et al.   LANCET

Trial of Satralizumab in Neuromyelitis Optica Spectrum Disorder

(2019) Takashi Yamamura et al.   NEW ENGLAND JOURNAL OF MEDICINE

Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions

(2018) Maximilien Evrard et al.   IMMUNITY

Plasma cell survival in the absence of B cell memory

(2017) Erika Hammarlund et al.   Nature Communications

Safety and pharmacodynamic dose response of short-term prednisone in healthy adult subjects: a dose ranging, randomized, placebo-controlled, crossover study

(2016) Dona L. Fleishaker et al.   BMC MUSCULOSKELETAL DISORDERS

A Regulatory Feedback between Plasmacytoid Dendritic Cells and Regulatory B Cells Is Aberrant in Systemic Lupus Erythematosus

(2016) Madhvi Menon et al.   IMMUNITY

Effect of tocilizumab on neutrophils in adult patients with rheumatoid arthritis: pooled analysis of data from phase 3 and 4 clinical trials

(2016) Robert J. Moots et al.   RHEUMATOLOGY

International consensus diagnostic criteria for neuromyelitis optica spectrum disorders

(2015) Dean M. Wingerchuk et al.   NEUROLOGY

Long-term Therapy With Interleukin 6 Receptor Blockade in Highly Active Neuromyelitis Optica Spectrum Disorder

(2015) Marius Ringelstein et al.   JAMA Neurology

Neutrophils Mediate Blood–Spinal Cord Barrier Disruption in Demyelinating Neuroinflammatory Diseases

(2014) Benoit Aubé et al.   JOURNAL OF IMMUNOLOGY

Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab

(2014) Manabu Araki et al.   Modern Rheumatology

Efficacy of the anti-IL-6 receptor antibody tocilizumab in neuromyelitis optica: A pilot study

(2014) M. Araki et al.   NEUROLOGY

Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial

(2013) Cem Gabay et al.   LANCET

Plasmablasts as Migratory IgG-Producing Cells in the Pathogenesis of Neuromyelitis Optica

(2013) Norio Chihara et al.   PLoS One

Interleukin 6 Receptor Blockade in Patients With Neuromyelitis Optica Nonresponsive to Anti-CD20 Therapy

(2013) Ilya Ayzenberg et al.   JAMA Neurology

B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6–producing B cells

(2012) Tom A. Barr et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Aquaporin 4 and neuromyelitis optica

(2012) Marios C Papadopoulos et al.   LANCET NEUROLOGY

Mucosal-associated invariant T cells regulate Th1 response in multiple sclerosis

(2011) Yusei Miyazaki et al.   INTERNATIONAL IMMUNOLOGY

Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica

(2011) Norio Chihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon Beta Treatment in Neuromyelitis Optica

(2010) Jacqueline Palace et al.   ARCHIVES OF NEUROLOGY

IL-6: Regulator of Treg/Th17 balance

(2010) Akihiro Kimura et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interferon-β1b Treatment in Neuromyelitis Optica

(2009) Masami Tanaka et al.   EUROPEAN NEUROLOGY

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Novel Human Transitional B Cell Populations Revealed by B Cell Depletion Therapy

(2009) Arumugam Palanichamy et al.   JOURNAL OF IMMUNOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols