A small molecule mitigates hearing loss in a mouse model of Usher syndrome III

Proteasome inhibitors induce auditory hair cell death through peroxisome dysfunction

(2015) Joon No Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein

(2015) S. R. Gopal et al.   JOURNAL OF NEUROSCIENCE

Organization of cGMP sensing structures on the rod photoreceptor outer segment plasma membrane

(2015) Ina Nemet et al.   Channels

Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration

(2014) Wei-Chieh Chiang et al.   MOLECULAR NEUROBIOLOGY

P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis

(2013) S. Sakami et al.   HUMAN MOLECULAR GENETICS

Signals Governing the Trafficking and Mistrafficking of a Ciliary GPCR, Rhodopsin

(2013) K. H. Lodowski et al.   JOURNAL OF NEUROSCIENCE

Chemical predictive modelling to improve compound quality

(2013) John G. Cumming et al.   NATURE REVIEWS DRUG DISCOVERY

Proteasome overload is a common stress factor in multiple forms of inherited retinal degeneration

(2013) E. S. Lobanova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteasome Inhibitors: An Expanding Army Attacking a Unique Target

(2012) Alexei F. Kisselev et al.   CHEMISTRY & BIOLOGY

The Mechanosensory Structure of the Hair Cell Requires Clarin-1, a Protein Encoded by Usher Syndrome III Causative Gene

(2012) R. Geng et al.   JOURNAL OF NEUROSCIENCE

Rescue of ΔF508-CFTR Trafficking via a GRASP-Dependent Unconventional Secretion Pathway

(2011) Heon Yung Gee et al.   CELL

Probing Mechanisms of Photoreceptor Degeneration in a New Mouse Model of the Common Form of Autosomal Dominant Retinitis Pigmentosa due to P23H Opsin Mutations

(2011) Sanae Sakami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Protein quality control in the ER: balancing the ubiquitin checkbook

(2011) Jasper H.L. Claessen et al.   TRENDS IN CELL BIOLOGY

SnapShot: The Unfolded Protein Response

(2010) R. Luke Wiseman et al.   CELL

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

(2010) Jonathan B. Baell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comprehensive genetic testing for hereditary hearing loss using massively parallel sequencing

(2010) A. E. Shearer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Usher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activation

(2009) R. Geng et al.   HUMAN MOLECULAR GENETICS

Clarin-1, Encoded by the Usher Syndrome III Causative Gene, Forms a Membranous Microdomain

(2009) Guilian Tian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomic Changes in the Photoreceptor Outer Segment upon Intense Light Exposure

(2009) Dagmar Hajkova et al.   JOURNAL OF PROTEOME RESEARCH

CLRN1 Is Nonessential in the Mouse Retina but Is Required for Cochlear Hair Cell Development

(2009) Scott F. Geller et al.   PLoS Genetics

Trafficking of immature ΔF508-CFTR to the plasma membrane and its detection by biotinylation

(2008) Yishan Luo et al.   BIOCHEMICAL JOURNAL