Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer

(2016) Himisha Beltran et al.   NATURE MEDICINE

Defects of CRB2 Cause Steroid-Resistant Nephrotic Syndrome

(2015) Lwaki Ebarasi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

CRB2 Mutations Produce a Phenotype Resembling Congenital Nephrosis, Finnish Type, with Cerebral Ventriculomegaly and Raised Alpha-Fetoprotein

(2015) Anne Slavotinek et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Myosin-II-mediated cell shape changes and cell intercalation contribute to primitive streak formation

(2015) Emil Rozbicki et al.   NATURE CELL BIOLOGY

Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

(2015) M Teresa Grande et al.   NATURE MEDICINE

Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis

(2015) Sara Lovisa et al.   NATURE MEDICINE

Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2

(2015) Nitya Ramkumar et al.   PLoS Genetics

Traffic jam in the primitive streak: The role of defective mesoderm migration in birth defects

(2014) Nils J. Herion et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

MAP2K1 (MEK1) Mutations Define a Distinct Subset of Lung Adenocarcinoma Associated with Smoking

(2014) M. E. Arcila et al.   CLINICAL CANCER RESEARCH

Local cell interactions and self-amplifying individual cell ingression drive amniote gastrulation

(2014) Octavian Voiculescu et al.   eLife

A functional role of the extracellular domain of Crumbs in cell architecture and apicobasal polarity

(2013) A. Letizia et al.   JOURNAL OF CELL SCIENCE

Crumbs3 Is Essential for Proper Epithelial Development and Viability

(2013) E. L. Whiteman et al.   MOLECULAR AND CELLULAR BIOLOGY

Positive Feedback and Mutual Antagonism Combine to Polarize Crumbs in the Drosophila Follicle Cell Epithelium

(2012) Georgina C. Fletcher et al.   CURRENT BIOLOGY

Anisotropy of Crumbs and aPKC Drives Myosin Cable Assembly during Tube Formation

(2012) Katja Röper   DEVELOPMENTAL CELL

Crb Apical Polarity Proteins Maintain Zebrafish Retinal Cone Mosaics via Intercellular Binding of Their Extracellular Domains

(2012) Jian Zou et al.   DEVELOPMENTAL CELL

Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene

(2012) Celso Henrique Alves et al.   HUMAN MOLECULAR GENETICS

Cancer stem cells and epithelial–mesenchymal transition: Concepts and molecular links

(2012) Christina Scheel et al.   SEMINARS IN CANCER BIOLOGY

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

The Apical Polarity Protein Network in Drosophila Epithelial Cells: Regulation of Polarity, Junctions, Morphogenesis, Cell Growth, and Survival

(2011) Ulrich Tepass   Annual Review of Cell and Developmental Biology

Rac1 mediates morphogenetic responses to intercellular signals in the gastrulating mouse embryo

(2011) I. Migeotte et al.   DEVELOPMENT

Reciprocal Repression between Sox3 and Snail Transcription Factors Defines Embryonic Territories at Gastrulation

(2011) Hervé Acloque et al.   DEVELOPMENTAL CELL

Deficiency in crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice

(2011) Zhijie Xiao et al.   DEVELOPMENTAL DYNAMICS

Mouse primitive streak forms in situ by initiation of epithelial to mesenchymal transition without migration of a cell population

(2011) Margot Williams et al.   DEVELOPMENTAL DYNAMICS

Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation

(2011) Takashi Ishiuchi et al.   NATURE CELL BIOLOGY

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Myosin II Dynamics Are Regulated by Tension in Intercalating Cells

(2009) Rodrigo Fernandez-Gonzalez et al.   DEVELOPMENTAL CELL

P115 RhoGEF and microtubules decide the direction apoptotic cells extrude from an epithelium

(2009) Gloria Slattum et al.   JOURNAL OF CELL BIOLOGY

Crumbs stabilises epithelial polarity during tissue remodelling

(2009) K. Campbell et al.   JOURNAL OF CELL SCIENCE

Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo

(2009) Sebastian J. Arnold et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

(2008) Jose Silva et al.   PLOS BIOLOGY