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NATURE CELL BIOLOGY
Volume 18, Issue 5, Pages 465-466Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ncb3352
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The liver is the most common metastatic route of pancreatic cancer. Early recruitment of granulin-secreting inflammatory monocytes to the liver is now shown to reprogram hepatic stellate cells into myofibroblasts that modulate the liver microenvironment to support the growth of metastasizing tumour cells.
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