miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding

Contribution of ADAM17 and related ADAMs in cardiovascular diseases

(2021) Tatsuo Kawai et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Chronic Intermittent Hypobaric Hypoxia Decreases High Blood Pressure by Stabilizing the Vascular Renin-Angiotensin System in Spontaneously Hypertensive Rats

(2021) Hua Chen et al.   Frontiers in Physiology

Hypertension genetics past, present and future applications

(2021) Kaya J. Olczak et al.   JOURNAL OF INTERNAL MEDICINE

Reciprocal control of ADAM17/EGFR/Akt signaling and miR-145 drives GBM invasiveness

(2020) Yuduo Guo et al.   JOURNAL OF NEURO-ONCOLOGY

Hsa_circ_0037897 may be a risk factor for essential hypertension via hsa-miR-145-5p

(2020) Zhenbo Tao et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Exploration of physiological and pathophysiological implications of miRNA-143 and miRNA-145 in cerebral arteries

(2019) Simon Topp Christensen et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

microRNA-331-3p maintains the contractile type of vascular smooth muscle cells by regulating TNF-α and CD14 in intracranial aneurysm

(2019) Weijian Fan et al.   NEUROPHARMACOLOGY

Extracellular oxidation in cystic fibrosis airway epithelium causes enhanced EGFR/ADAM17 activity

(2018) Marta Stolarczyk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The lncRNA TUG1/miR-145-5p/FGF10 regulates proliferation and migration in VSMCs of hypertension

(2018) Lin Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of melatonin in blood pressure regulation: An adjunct anti-hypertensive agent

(2018) Jacquie Baker et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Loss of smooth muscle cell disintegrin and metalloproteinase 17 transiently suppresses angiotensin II-induced hypertension and end-organ damage

(2017) Mengcheng Shen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Local Renin Angiotensin Aldosterone Systems and Cardiovascular Diseases

(2017) Walmor C. De Mello   MEDICAL CLINICS OF NORTH AMERICA

Vascular ADAM17 as a Novel Therapeutic Target in Mediating Cardiovascular Hypertrophy and Perivascular Fibrosis Induced by Angiotensin IINovelty and Significance

(2016) Takehiko Takayanagi et al.   HYPERTENSION

Circulating Toll-like receptor 4-responsive microRNA panel in patients with coronary artery disease: results from prospective and randomized study of treatment with renin–angiotensin system blockade

(2015) Mamoru Satoh et al.   CLINICAL SCIENCE

MiR-145, a microRNA targeting ADAM17, inhibits the invasion and migration of nasopharyngeal carcinoma cells

(2015) Jing Wu et al.   EXPERIMENTAL CELL RESEARCH

Matrix Metalloproteinases Promote Arterial Remodeling in Aging, Hypertension, and Atherosclerosis

(2015) M. Wang et al.   HYPERTENSION

Human miR-221/222 in Physiological and Atherosclerotic Vascular Remodeling

(2015) Dmitry A. Chistiakov et al.   Biomed Research International

MicroRNA-145 Targets the Metalloprotease ADAM17 and Is Suppressed in Renal Cell Carcinoma Patients

(2015) Kai Doberstein et al.   NEOPLASIA

Expression of miR-224, miR-145, and their putative target ADAM17 in hepatocellular carcinoma

(2014) Yuwu Liu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

MicroRNA-145 inhibits cell proliferation by directly targeting ADAM17 in hepatocellular carcinoma

(2014) YUWU LIU et al.   ONCOLOGY REPORTS

Mechanical Stretch Suppresses microRNA-145 Expression by Activating Extracellular Signal-Regulated Kinase 1/2 and Upregulating Angiotensin-Converting Enzyme to Alter Vascular Smooth Muscle Cell Phenotype

(2014) Bo Hu et al.   PLoS One

miR-145 suppresses cell invasion in hepatocellular carcinoma cells: miR-145 targets ADAM17

(2013) Xue-wei Yang et al.   HEPATOLOGY RESEARCH

Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: A positive feedback mechanism in the RAS

(2013) Vaibhav B. Patel et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MiR-145 reduces ADAM17 expression and inhibits in vitro migration and invasion of glioma cells

(2012) YONG LU et al.   ONCOLOGY REPORTS

MicroRNA-130a Mediates Proliferation of Vascular Smooth Muscle Cells in Hypertension

(2011) W.-H. Wu et al.   AMERICAN JOURNAL OF HYPERTENSION

Angiotensin-Converting Enzyme 2: Central Regulator for Cardiovascular Function

(2010) Huijing Xia et al.   CURRENT HYPERTENSION REPORTS

miR-145 and miR-143 regulate smooth muscle cell fate and plasticity

(2009) Kimberly R. Cordes et al.   NATURE

Notch and Vascular Smooth Muscle Cell Phenotype

(2008) David Morrow et al.   CIRCULATION RESEARCH