Consistency in large pharmacogenomic studies

Predicting response to multidrug regimens in cancer patients using cell line experiments and regularised regression models

(2015) Steffen Falgreen et al.   BMC CANCER

Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell lines

(2014) Paul Geeleher et al.   GENOME BIOLOGY

Crizotinib for the treatment of non-small-cell lung cancer

(2013) A. Timm et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Inconsistency in large pharmacogenomic studies

(2013) Benjamin Haibe-Kains et al.   NATURE

Systematic identification of genomic markers of drug sensitivity in cancer cells

(2012) Mathew J. Garnett et al.   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Transcriptional Pathway Signatures Predict MEK Addiction and Response to Selumetinib (AZD6244)

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Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

(2008) J. Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA