Circuit-based interrogation of sleep control

Evidence that Neurons of the Sublaterodorsal Tegmental Nucleus Triggering Paradoxical (REM) Sleep Are Glutamatergic

(2017) Olivier Clément et al.   SLEEP

An Adenosine-Mediated Glial-Neuronal Circuit for Homeostatic Sleep

(2016) Theresa E. Bjorness et al.   JOURNAL OF NEUROSCIENCE

Cholinergic Neurons in the Basal Forebrain Promote Wakefulness by Actions on Neighboring Non-Cholinergic Neurons: An Opto-Dialysis Study

(2016) J. C. Zant et al.   JOURNAL OF NEUROSCIENCE

Slow waves, sharp waves, ripples, and REM in sleeping dragons

(2016) Mark Shein-Idelson et al.   SCIENCE

Call it Worm Sleep

(2016) Nicholas F. Trojanowski et al.   TRENDS IN NEUROSCIENCES

Calcium imaging of sleep–wake related neuronal activity in the dorsal pons

(2016) Julia Cox et al.   Nature Communications

A Conserved Bicycle Model for Circadian Clock Control of Membrane Excitability

(2015) Matthieu Flourakis et al.   CELL

Optogenetic Evidence for Inhibitory Signaling from Orexin to MCH Neurons via Local Microcircuits

(2015) J. Apergis-Schoute et al.   JOURNAL OF NEUROSCIENCE

Glucose Induces Slow-Wave Sleep by Exciting the Sleep-Promoting Neurons in the Ventrolateral Preoptic Nucleus: A New Link between Sleep and Metabolism

(2015) C. Varin et al.   JOURNAL OF NEUROSCIENCE

Control of REM sleep by ventral medulla GABAergic neurons

(2015) Franz Weber et al.   NATURE

Basal forebrain circuit for sleep-wake control

(2015) Min Xu et al.   NATURE NEUROSCIENCE

Neuronal ensembles sufficient for recovery sleep and the sedative actions of α2 adrenergic agonists

(2015) Zhe Zhang et al.   NATURE NEUROSCIENCE

Wakefulness Is Governed by GABA and Histamine Cotransmission

(2015) Xiao Yu et al.   NEURON

Structural foundations of optogenetics: Determinants of channelrhodopsin ion selectivity

(2015) Andre Berndt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cells of a common developmental origin regulate REM/non-REM sleep and wakefulness in mice

(2015) Y. Hayashi et al.   SCIENCE

State-Dependent Architecture of Thalamic Reticular Subnetworks

(2014) Michael M. Halassa et al.   CELL

Selective Activation of Cholinergic Basal Forebrain Neurons Induces Immediate Sleep-wake Transitions

(2014) Yong Han et al.   CURRENT BIOLOGY

What optogenetic stimulation is telling us (and failing to tell us) about fast neurotransmitters and neuromodulators in brain circuits for wake–sleep regulation

(2014) Elda Arrigoni et al.   CURRENT OPINION IN NEUROBIOLOGY

Endogenous Cholinergic Input to the Pontine REM Sleep Generator Is Not Required for REM Sleep to Occur

(2014) K. P. Grace et al.   JOURNAL OF NEUROSCIENCE

Cholinergic Neurons Excite Cortically Projecting Basal Forebrain GABAergic Neurons

(2014) C. Yang et al.   JOURNAL OF NEUROSCIENCE

Discharge Profiles across the Sleep-Waking Cycle of Identified Cholinergic, GABAergic, and Glutamatergic Neurons in the Pontomesencephalic Tegmentum of the Rat

(2014) S. Boucetta et al.   JOURNAL OF NEUROSCIENCE

Optogenetic Manipulation of Activity and Temporally Controlled Cell-Specific Ablation Reveal a Role for MCH Neurons in Sleep/Wake Regulation

(2014) T. Tsunematsu et al.   JOURNAL OF NEUROSCIENCE

Galanin neurons in the medial preoptic area govern parental behaviour

(2014) Zheng Wu et al.   NATURE

A mesoscale connectome of the mouse brain

(2014) Seung Wook Oh et al.   NATURE

The GABAergic parafacial zone is a medullary slow wave sleep–promoting center

(2014) Christelle Anaclet et al.   NATURE NEUROSCIENCE

Sleep and the Price of Plasticity: From Synaptic and Cellular Homeostasis to Memory Consolidation and Integration

(2014) Giulio Tononi et al.   NEURON

The Inhibition of the Dorsal Paragigantocellular Reticular Nucleus Induces Waking and the Activation of All Adrenergic and Noradrenergic Neurons: A Combined Pharmacological and Functional Neuroanatomical Study

(2014) Olivier Clément et al.   PLoS One

Optogenetic activation of cholinergic neurons in the PPT or LDT induces REM sleep

(2014) Christa J. Van Dort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenosine A2A receptors regulate the activity of sleep regulatory GABAergic neurons in the preoptic hypothalamus

(2013) Sunil Kumar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Sleep homeostasis

(2013) Tarja Porkka-Heiskanen   CURRENT OPINION IN NEUROBIOLOGY

Sites of action of sleep and wake drugs: insights from model organisms

(2013) Jason Rihel et al.   CURRENT OPINION IN NEUROBIOLOGY

Neuronal activity in the preoptic hypothalamus during sleep deprivation and recovery sleep

(2013) Md. Aftab Alam et al.   JOURNAL OF NEUROPHYSIOLOGY

Optogenetic Stimulation of MCH Neurons Increases Sleep

(2013) R. R. Konadhode et al.   JOURNAL OF NEUROSCIENCE

Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus

(2013) Sonia Jego et al.   NATURE NEUROSCIENCE

Design and generation of recombinant rabies virus vectors

(2013) Fumitaka Osakada et al.   Nature Protocols

A role for cortical nNOS/NK1 neurons in coupling homeostatic sleep drive to EEG slow wave activity

(2013) S. R. Morairty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and Characterization of a Sleep-Active Cell Group in the Rostral Medullary Brainstem

(2012) C. Anaclet et al.   JOURNAL OF NEUROSCIENCE

Control of Sleep and Wakefulness

(2012) Ritchie E. Brown et al.   PHYSIOLOGICAL REVIEWS

Genetics of Sleep and Sleep Disorders

(2011) Amita Sehgal et al.   CELL

Brainstem and Spinal Cord Circuitry Regulating REM Sleep and Muscle Atonia

(2011) Martina Krenzer et al.   PLoS One

GABAergic neurons intermingled with orexin and MCH neurons in the lateral hypothalamus discharge maximally during sleep

(2010) Oum Kaltoum Hassani et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Reassessment of the structural basis of the ascending arousal system

(2010) Patrick Fuller et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Histamine regulates activities of neurons in the ventrolateral preoptic nucleus

(2010) Yu-Wei Liu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Optogenetics

(2010) Karl Deisseroth   NATURE METHODS

Tuning arousal with optogenetic modulation of locus coeruleus neurons

(2010) Matthew E Carter et al.   NATURE NEUROSCIENCE

Sleep State Switching

(2010) Clifford B. Saper et al.   NEURON

Discharge Profiles of Identified GABAergic in Comparison to Cholinergic and Putative Glutamatergic Basal Forebrain Neurons across the Sleep-Wake Cycle

(2009) O. K. Hassani et al.   JOURNAL OF NEUROSCIENCE

Control and Function of the Homeostatic Sleep Response by Adenosine A1 Receptors

(2009) T. E. Bjorness et al.   JOURNAL OF NEUROSCIENCE

Astrocytic Modulation of Sleep Homeostasis and Cognitive Consequences of Sleep Loss

(2009) Michael M. Halassa et al.   NEURON

Characterization and mapping of sleep–waking specific neurons in the basal forebrain and preoptic hypothalamus in mice

(2009) K. Takahashi et al.   NEUROSCIENCE

Localization of the Brainstem GABAergic Neurons Controlling Paradoxical (REM) Sleep

(2009) Emilie Sapin et al.   PLoS One

Melanin-concentrating hormone neurons discharge in a reciprocal manner to orexin neurons across the sleep-wake cycle

(2009) O. K. Hassani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetics of Sleep

(2008) Rozi Andretic et al.   Annual Review of Genetics

Opioidergic projections to sleep-active neurons in the ventrolateral preoptic nucleus

(2008) Mary-Ann Greco et al.   BRAIN RESEARCH

Regulation of Synaptic Efficacy in Hypocretin/Orexin-Containing Neurons by Melanin Concentrating Hormone in the Lateral Hypothalamus

(2008) Y. Rao et al.   JOURNAL OF NEUROSCIENCE

The role of cholinergic basal forebrain neurons in adenosine-mediated homeostatic control of sleep: Lessons from 192 IgG–saporin lesions

(2008) A.V. Kalinchuk et al.   NEUROSCIENCE

Identification of a population of sleep-active cerebral cortex neurons

(2008) D. Gerashchenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenosine in the tuberomammillary nucleus inhibits the histaminergic system via A1 receptors and promotes non-rapid eye movement sleep

(2008) Y. Oishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA