Crystal structure of the human σ1 receptor

The sigma-1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligands

(2015) Ashish K. Mishra et al.   BIOCHEMICAL JOURNAL

Role of sigma-1 receptors in neurodegenerative diseases

(2015) Linda Nguyen et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Role of the Sigma-1 receptor in Amyotrophic Lateral Sclerosis (ALS)

(2015) Timur A. Mavlyutov et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Methyl pyruvate rescues mitochondrial damage caused by SIGMAR1 mutation related to amyotrophic lateral sclerosis

(2014) Hideaki Tagashira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Oligomeric States of the Purified Sigma-1 Receptor Are Stabilized by Ligands

(2014) Katarzyna A. Gromek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lack of sigma-1 receptor exacerbates ALS progression in mice

(2013) T.A. Mavlyutov et al.   NEUROSCIENCE

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A mutation in sigma-1 receptor causes juvenile amyotrophic lateral sclerosis

(2011) Amr Al-Saif et al.   ANNALS OF NEUROLOGY

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

(2011) Søren G. F. Rasmussen et al.   NATURE

OPM database and PPM web server: resources for positioning of proteins in membranes

(2011) Mikhail A. Lomize et al.   NUCLEIC ACIDS RESEARCH

 1 Receptor Modulation of G-Protein-Coupled Receptor Signaling: Potentiation of Opioid Transduction Independent from Receptor Binding

(2010) F. J. Kim et al.   MOLECULAR PHARMACOLOGY

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

(2010) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

The sigma-1 receptor chaperone as an inter-organelle signaling modulator

(2010) Tsung-Ping Su et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Pharmacology and Therapeutic Potential of Sigma1 Receptor Ligands

(2009) E. Cobos et al.   Current Neuropharmacology

Crystallizing membrane proteins using lipidic mesophases

(2009) Martin Caffrey et al.   Nature Protocols

The pharmacology of sigma-1 receptors

(2009) Tangui Maurice et al.   PHARMACOLOGY & THERAPEUTICS

Role of Sigma-1 Receptor C-terminal Segment in Inositol 1,4,5-Trisphosphate Receptor Activation

(2008) Zhiping Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY