Transfer and biotransformation of the COVID-19 prodrug molnupiravir and its metabolite β-D-N4-hydroxycytidine across the blood-placenta barrier

Pharmacokinetics of ß-d-N4-Hydroxycytidine, the Parent Nucleoside of Prodrug Molnupiravir, in Nonplasma Compartments of Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection

(2022) Richard FitzGerald et al.   CLINICAL INFECTIOUS DISEASES

Biotransformation and transplacental transfer of the anti-viral remdesivir and predominant metabolite, GS-441524 in pregnant rats

(2022) Ling Yang et al.   EBioMedicine

Human Safety, Tolerability, and Pharmacokinetics of Molnupiravir, a Novel Broad-Spectrum Oral Antiviral Agent with Activity Against SARS-CoV-2

(2021) Wendy P. Painter et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template

(2021) Calvin J. Gordon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Remdesivir and EIDD-1931 Interact with Human Equilibrative Nucleoside Transporters 1 and 2: Implications for Reaching SARS-CoV-2 Viral Sanctuary Sites

(2021) Siennah R. Miller et al.   MOLECULAR PHARMACOLOGY

Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis

(2021) Florian Kabinger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Trans-placental transfer of nicotine: Modulation by organic cation transporters

(2021) I-Hsin Lin et al.   BIOMEDICINE & PHARMACOTHERAPY

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records

(2020) Huijun Chen et al.   LANCET

Clinical Characteristics of 46 Pregnant Women with a SARS-CoV-2 Infection in Washington State

(2020) Erica M. Lokken et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Analysis of vaginal delivery outcomes among pregnant women in Wuhan, China during the COVID‐19 pandemic

(2020) Jing Liao et al.   INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vertical Transmission in Neonates Born to Mothers With Coronavirus Disease 2019 (COVID-19) Pneumonia

(2020) Xiaolin Hu et al.   OBSTETRICS AND GYNECOLOGY

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

(2020) Timothy P. Sheahan et al.   Science Translational Medicine

Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro

(2020) Ka-Tim Choy et al.   ANTIVIRAL RESEARCH

The tragedy of COVID‐19 in Brazil: 124 maternal deaths and counting

(2020) Maira L. S. Takemoto et al.   INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

Characteristics of Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status — United States, January 22–June 7, 2020

(2020) Sascha Ellington et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

SARS–CoV-2 infection of the placenta

(2020) Hillary Hosier et al.   JOURNAL OF CLINICAL INVESTIGATION

Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia

(2019) Mart Toots et al.   Science Translational Medicine

Expression of Concentrative Nucleoside Transporters (SLC28A) in the Human Placenta: Effects of Gestation Age and Prototype Differentiation-Affecting Agents

(2018) Lucie Jiraskova et al.   MOLECULAR PHARMACEUTICS

Maternal use of drug substrates of placental transporters and the effect of transporter-mediated drug interactions on the risk of congenital anomalies

(2017) Aizati N. A. Daud et al.   PLoS One

Population pharmacokinetics, optimised design and sample size determination for rifampicin, isoniazid, ethambutol and pyrazinamide in the mouse

(2016) Chunli Chen et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Transporter-Mediated Drug Uptake and Efflux: Important Determinants of Adverse Drug Reactions

(2011) O Zolk et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS