Longitudinal evaluation of the biodistribution and cellular internalization of the bispecific CD3xTRP1 antibody in syngeneic mouse tumor models
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Longitudinal evaluation of the biodistribution and cellular internalization of the bispecific CD3xTRP1 antibody in syngeneic mouse tumor models
Authors
Keywords
-
Journal
Journal for ImmunoTherapy of Cancer
Volume 11, Issue 10, Pages e007596
Publisher
BMJ
Online
2023-10-30
DOI
10.1136/jitc-2023-007596
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Humanization of a strategic CD3 epitope enables evaluation of clinical T-cell engagers in a fully immunocompetent in vivo model
- (2022) Julie A. Zorn et al. Scientific Reports
- PD-L1 Antibody Pharmacokinetics and Tumor Targeting in Mouse Models for Infectious Diseases
- (2022) Gerwin G. W. Sandker et al. Frontiers in Immunology
- Overcoming the challenges associated with CD3+ T-cell redirection in cancer
- (2021) Ajit Singh et al. BRITISH JOURNAL OF CANCER
- Overcoming Challenges for CD3-Bispecific Antibody Therapy in Solid Tumors
- (2021) Jim Middelburg et al. Cancers
- Bispecific T cell engagers: an emerging therapy for management of hematologic malignancies
- (2021) Zheng Tian et al. Journal of Hematology & Oncology
- Bispecific Antibodies: A Review of Development, Clinical Efficacy and Toxicity in B-Cell Lymphomas
- (2021) Ross Salvaris et al. Journal of Personalized Medicine
- Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning
- (2021) Lauric Haber et al. Scientific Reports
- Dichotomous impact of affinity on the function of T cell engaging bispecific antibodies
- (2021) Mathilde Poussin et al. Journal for ImmunoTherapy of Cancer
- Bispecific Antibodies: A Smart Arsenal for Cancer Immunotherapies
- (2021) Gihoon You et al. Vaccines
- Macropinocytosis drives T cell growth by sustaining the activation of mTORC1
- (2020) John C. Charpentier et al. Nature Communications
- Macropinocytosis Renders a Subset of Pancreatic Tumor Cells Resistant to mTOR Inhibition
- (2020) Evdokia Michalopoulou et al. Cell Reports
- Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies
- (2020) Hui Yi Chew et al. CELL
- Biodistribution of a CD3/EpCAM bispecific T-cell engager is driven by the CD3 arm
- (2020) Frans V. Suurs et al. JOURNAL OF NUCLEAR MEDICINE
- Endocytosis in cellular uptake of drug delivery vectors: Molecular aspects in drug development
- (2020) Zuzanna Kaźmierczak et al. BIOORGANIC & MEDICINAL CHEMISTRY
- A Mucin 16 bispecific T cell–engaging antibody for the treatment of ovarian cancer
- (2019) Alison Crawford et al. Science Translational Medicine
- Is there a place and role for endocytic TCR signaling?
- (2019) Loredana Saveanu et al. IMMUNOLOGICAL REVIEWS
- Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cells
- (2019) Chenxi Tian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Relative Target Affinities of T-Cell–Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model
- (2018) Danielle Mandikian et al. MOLECULAR CANCER THERAPEUTICS
- Bispecific T-cell engagers: Towards understanding variables influencing the in vitro potency and tumor selectivity and their modulation to enhance their efficacy and safety
- (2018) Diego Ellerman METHODS
- CD3-bispecific antibody therapy turns solid tumors into inflammatory sites but does not install protective memory
- (2018) Hreinn Benonisson et al. MOLECULAR CANCER THERAPEUTICS
- Efficient Generation of Bispecific Murine Antibodies for Pre-Clinical Investigations in Syngeneic Rodent Models
- (2017) Aran F. Labrijn et al. Scientific Reports
- Biodistribution and PET Imaging of Labeled Bispecific T Cell-Engaging Antibody Targeting EpCAM
- (2016) F. J. Warnders et al. JOURNAL OF NUCLEAR MEDICINE
- Novel human IgG1 and IgG4 Fc-engineered antibodies with completely abolished immune effector functions
- (2016) Tilman Schlothauer et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Increase of PD-L1 expressing B-precursor ALL cells in a patient resistant to the CD19/CD3-bispecific T cell engager antibody blinatumomab
- (2015) Thomas Köhnke et al. Journal of Hematology & Oncology
- Blockade of the PD-1/PD-L1 axis augments lysis of AML cells by the CD33/CD3 BiTE antibody construct AMG 330: reversing a T-cell-induced immune escape mechanism
- (2015) C Krupka et al. LEUKEMIA
- Retargeting T Cells to GD2 Pentasaccharide on Human Tumors Using Bispecific Humanized Antibody
- (2014) H. Xu et al. Cancer Immunology Research
- Characterization of a surrogate murine antibody to model anti-human CD3 therapies
- (2013) Fabien Dépis et al. mAbs
- An integrated approach to identify normal tissue expression of targets for antibody-drug conjugates: case study of TENB2
- (2012) C Andrew Boswell et al. BRITISH JOURNAL OF PHARMACOLOGY
- Influence of Affinity and Antigen Internalization on the Uptake and Penetration of Anti-HER2 Antibodies in Solid Tumors
- (2011) S. I. Rudnick et al. CANCER RESEARCH
- Antibody tumor penetration: Transport opposed by systemic and antigen-mediated clearance
- (2008) Greg M. Thurber et al. ADVANCED DRUG DELIVERY REVIEWS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search