CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis

Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

(2023) Anastasios D. Giannou et al.   IMMUNITY

T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis

(2023) Daria Briukhovetska et al.   IMMUNITY

Rationalizing heptadecaphobia: T H 17 cells and associated cytokines in cancer and metastasis

(2021) Jöran Lücke et al.   FEBS Journal

Targeting metastatic cancer

(2021) Karuna Ganesh et al.   NATURE MEDICINE

Exhausted CD8+T Cells in the Tumor Immune Microenvironment: New Pathways to Therapy

(2021) Weiqin Jiang et al.   Frontiers in Immunology

The good and the bad about separation anxiety: roles of IL-22 and IL-22BP in liver pathologies

(2021) Jöran Lücke et al.   Seminars in Immunopathology

TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer

(2020) Laura Garcia Perez et al.   Nature Communications

Critical steps to tumor metastasis: alterations of tumor microenvironment and extracellular matrix in the formation of pre-metastatic and metastatic niche

(2020) Jianan Zhuyan et al.   Cell and Bioscience

Cytotoxic CD8+ T cells in cancer and cancer immunotherapy

(2020) Hans Raskov et al.   BRITISH JOURNAL OF CANCER

Microbiota-Dependent Effects of IL-22

(2020) Morsal Sabihi et al.   Cells

Defining the Hallmarks of Metastasis

(2019) Danny R. Welch et al.   CANCER RESEARCH

IL-22RA1/ STAT3 signaling promotes stemness and tumorigenicity in pancreatic cancer

(2018) Weizhi He et al.   CANCER RESEARCH

TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis

(2018) Daniele V. F. Tauriello et al.   NATURE

Metastatic niche functions and therapeutic opportunities

(2018) Toni Celià-Terrassa et al.   NATURE CELL BIOLOGY

Targeting interleukin-22 for cancer therapy

(2018) Anamarija Markota et al.   Human Vaccines & Immunotherapeutics

Interleukin-22 promotes tumor angiogenesis

(2018) Nicholas J. Protopsaltis et al.   ANGIOGENESIS

Immune regulation of metastasis: mechanistic insights and therapeutic opportunities

(2018) Olga S. Blomberg et al.   Disease Models & Mechanisms

Contribution of regulatory T cells to cancer: A review

(2018) Masoud Najafi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review

(2018) Bagher Farhood et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Regulation of TH17 Cells and Associated Cytokines in Wound Healing, Tissue Regeneration, and Carcinogenesis

(2017) Leonie Brockmann et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CCL26 Participates in the PRL-3–Induced Promotion of Colorectal Cancer Invasion by Stimulating Tumor-Associated Macrophage Infiltration

(2017) Qiusheng Lan et al.   MOLECULAR CANCER THERAPEUTICS

The immune system in cancer metastasis: friend or foe?

(2017) Louise M.E. Janssen et al.   Journal for ImmunoTherapy of Cancer

P2X1-regulated IL-22 secretion by innate lymphoid cells is required for efficient liver regeneration

(2016) Ramesh Kudira et al.   HEPATOLOGY

IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis

(2015) Seth B. Coffelt et al.   NATURE

The role of the IL-22/IL-22R1 axis in cancer

(2014) Chrissie Lim et al.   CYTOKINE & GROWTH FACTOR REVIEWS

IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1L

(2014) Ilona Kryczek et al.   IMMUNITY

Pro-tumour activity of interleukin-22 in HPAFII human pancreatic cancer cells

(2012) L. M. Curd et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Activated tumor-infiltrating CD4+ regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer

(2012) Alexander Pedroza-Gonzalez et al.   HEPATOLOGY

Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3− and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner

(2011) Samuel Huber et al.   IMMUNITY

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE