Highly recruited brown adipose tissue does not in itself protect against obesity

Cold acclimation and pioglitazone combined increase thermogenic capacity of brown and white adipose tissues but this does not translate into higher energy expenditure in mice

(2023) Luís Felipe Galvão Valdivia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Brown adipose tissue: can it keep us slim? A discussion of the evidence for and against the existence of diet-induced thermogenesis in mice and men

(2023) Jan Nedergaard et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Molecular and Physiological Effects of Browning Agents on White Adipocytes from Bone Marrow Mesenchymal Stromal Cells

(2022) Girolamo Di Maio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The gravitostat protects diet‐induced obese rats against fat accumulation and weight gain

(2021) Tina Bake et al.   JOURNAL OF NEUROENDOCRINOLOGY

Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice

(2020) Susanne Keipert et al.   Nature Communications

Regulation of Adaptive Thermogenesis and Browning by Prebiotics and Postbiotics

(2019) Bàrbara Reynés et al.   Frontiers in Physiology

Leptin – is it thermogenic?

(2019) Alexander W Fischer et al.   ENDOCRINE REVIEWS

Evidence for a Non-leptin System that Defends against Weight Gain in Overfeeding

(2018) Yann Ravussin et al.   Cell Metabolism

Why lipostatic set point systems are unlikely to evolve

(2018) John R. Speakman   Molecular Metabolism

Optimal housing temperatures for mice to mimic the thermal environment of humans: An experimental study

(2018) Alexander W. Fischer et al.   Molecular Metabolism

Intact innervation is essential for diet-induced recruitment of brown adipose tissue

(2018) Alexander W. Fischer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Dissociation Between Brown Adipose Tissue 18 F-FDG Uptake and Thermogenesis in Uncoupling Protein 1–Deficient Mice

(2017) Mohammed K. Hankir et al.   JOURNAL OF NUCLEAR MEDICINE

UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction

(2017) Lawrence Kazak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Body weight homeostat that regulates fat mass independently of leptin in rats and mice

(2017) John-Olov Jansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β 3 -Adrenergically induced glucose uptake in brown adipose tissue is independent of UCP1 presence or activity: Mediation through the mTOR pathway

(2017) Jessica M. Olsen et al.   Molecular Metabolism

A BAT-Centric Approach to the Treatment of Diabetes: Turn on the Brain

(2016) Mohammed K. Hankir et al.   Cell Metabolism

Convertible visceral fat as a therapeutic target to curb obesity

(2016) Antonio Giordano et al.   NATURE REVIEWS DRUG DISCOVERY

Sarcolipin and uncoupling protein 1 play distinct roles in diet-induced thermogenesis and do not compensate for one another

(2016) Leslie A. Rowland et al.   Obesity

Leptin Raises Defended Body Temperature without Activating Thermogenesis

(2016) Alexander W. Fischer et al.   Cell Reports

Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis

(2015) Labros Sidossis et al.   JOURNAL OF CLINICAL INVESTIGATION

The Browning of White Adipose Tissue: Some Burning Issues

(2014) Jan Nedergaard et al.   Cell Metabolism

The Chemical Uncoupler 2,4-Dinitrophenol (DNP) Protects against Diet-induced Obesity and Improves Energy Homeostasis in Mice at Thermoneutrality

(2014) Margalit Goldgof et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The different shades of fat

(2014) Vivian Peirce et al.   NATURE

A New Era in Brown Adipose Tissue Biology: Molecular Control of Brown Fat Development and Energy Homeostasis

(2013) Shingo Kajimura et al.   Annual Review of Physiology

Adaptive thermogenesis in adipocytes: Is beige the new brown?

(2013) J. Wu et al.   GENES & DEVELOPMENT

UCP1 in Brite/Beige Adipose Tissue Mitochondria Is Functionally Thermogenic

(2013) Irina G. Shabalina et al.   Cell Reports

Assessment of brown adipose tissue function

(2013) Sam Virtue et al.   Frontiers in Physiology

Below Thermoneutrality, Changes in Activity Do Not Drive Changes in Total Daily Energy Expenditure between Groups of Mice

(2012) Sam Virtue et al.   Cell Metabolism

Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity

(2011) J. R. Speakman et al.   Disease Models & Mechanisms

Uncoupling protein-1 is not leaky

(2010) Irina G. Shabalina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Nonshivering thermogenesis and its adequate measurement in metabolic studies

(2010) B. Cannon et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Decreased food intake following overfeeding involves leptin-dependent and leptin-independent mechanisms

(2010) Christy L. White et al.   PHYSIOLOGY & BEHAVIOR

Beige Can Be Slimming

(2010) J. Ishibashi et al.   SCIENCE

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

(2009) Natasa Petrovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thermogenesis challenges the adipostat hypothesis for body-weight control

(2009) Barbara Cannon et al.   PROCEEDINGS OF THE NUTRITION SOCIETY