Impact of concerning excipients on animal safety: insights for veterinary pharmacotherapy and regulatory considerations

Immunogenicity of Different Types of Adjuvants and Nano-Adjuvants in Veterinary Vaccines: A Comprehensive Review

(2023) Soren Nooraei et al.   Vaccines

Polysorbate 80-Induced Anaphylactoid Reaction and the Effects on Cardiovascular Function: Dose Threshold and Species Comparison

(2022) Mylène Pouliot et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Threshold for Anaphylactoid Reaction to Polysorbate 80 in Canines

(2022) Kristen Holbrook et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Effects of polyol excipient stability during storage and use on the quality of biopharmaceutical formulations

(2022) Min-Fei Sun et al.   Journal of Pharmaceutical Analysis

Comprehensive Review on the Interactions of Clay Minerals With Animal Physiology and Production

(2022) Anna Damato et al.   Frontiers in Veterinary Science

The Current States, Challenges, Ongoing Efforts, and Future Perspectives of Pharmaceutical Excipients in Pediatric Patients in Each Country and Region

(2022) Jumpei Saito et al.   Children-Basel

Evaluation of PEG-L-asparaginase in asparagine suppression and anti-drug antibody development in healthy Beagle dogs: A multi-phase preclinical study

(2022) L.R. Feenstra et al.   VETERINARY JOURNAL

UK veterinary professionals’ perceptions and experiences of adverse drug reaction reporting

(2022) Heather Davies et al.   VETERINARY RECORD

Canine and feline P‐glycoprotein deficiency: What we know and where we need to go

(2022) Katrina L. Mealey et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies

(2021) Bing-Mae Chen et al.   ACS Nano

Additives in pet food: are they safe?

(2021) J. M. Craig   JOURNAL OF SMALL ANIMAL PRACTICE

Immediate Hypersensitivity Reactions Caused by Drug Excipients: A Literature Review

(2020) ML Caballero et al.   JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY

A Comprehensive Scientific Survey of Excipients Used in Currently Marketed, Therapeutic Biological Drug Products

(2020) V. Ashutosh Rao et al.   PHARMACEUTICAL RESEARCH

Comparison of the effects of 7.2% hypertonic saline and 20% mannitol on electrolyte and acid‐base variables in dogs with suspected intracranial hypertension

(2020) Sabrina N. Hoehne et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Higher risk of xylitol gum poisoning with some products

(2019) Nicola Bates et al.   VETERINARY RECORD

Potential adverse effects on animal health and performance caused by the addition of mineral adsorbents to feeds to reduce mycotoxin exposure

(2019) Christopher T. Elliott et al.   Mycotoxin Research

Acute kidney injury, seizures, and hypertonic hyponatremia secondary to mannitol intoxication in a dog

(2019) Maëlle F. Clabots et al.   JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE

Review of the physicochemical methods applied in the investigation of the maillard reaction in pharmaceutical preparations

(2019) Faranak Ghaderi et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Novel excipients – Regulatory challenges and perspectives – The EU insight

(2018) Piotr Kozarewicz et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Effects of p.o. administered xylitol in cats

(2018) Á. Jerzsele et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Xylitol Toxicosis in Dogs

(2018) Lisa A. Murphy et al.   VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE

An Overview of Trends in Animal Poisoning Cases in the United States: 2011 to 2017

(2018) Charlotte Means et al.   VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE

Acute, Fatal, Presumptive Xylitol Toxicosis in Cape Sugarbirds (Promerops cafer)

(2017) Brett Richard Gardner et al.   JOURNAL OF AVIAN MEDICINE AND SURGERY

Zeolite A effect on calcium homeostasis in growing goats1

(2016) D. Schwaller et al.   JOURNAL OF ANIMAL SCIENCE

An Overview of Pharmaceutical Excipients: Safe or Not Safe?

(2016) Cátia G. Abrantes et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The effects of monosodium l-glutamate administration on the reproduction and serum biochemistry of adult male rabbits

(2016) CN Okoye et al.   VETERINARNI MEDICINA

Retrospective evaluation of xylitol ingestion in dogs: 192 cases (2007-2012)

(2015) Meghan R. DuHadway et al.   JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE

Pharmacokinetics and pharmacodynamics of propofol with or without 2% benzyl alcohol following a single induction dose administered intravenously in cats

(2015) Gregg M Griffenhagen et al.   VETERINARY ANAESTHESIA AND ANALGESIA

Potential cutaneous hypersensitivity reaction to an inactive ingredient of thyroid hormone supplements in a dog

(2015) Sidonie N. Lavergne et al.   VETERINARY DERMATOLOGY

Clinical effect of four different ointment bases on healthy cat eyes

(2015) Réka Eördögh et al.   VETERINARY OPHTHALMOLOGY

Importance and globalization status of good manufacturing practice (GMP) requirements for pharmaceutical excipients

(2015) Abubaker Abdellah et al.   SAUDI PHARMACEUTICAL JOURNAL

Tween-80 and impurity induce anaphylactoid reaction in zebrafish

(2014) Rui Yang et al.   JOURNAL OF APPLIED TOXICOLOGY

The Severe Adverse Reaction to Vitamin K1 Injection Is Anaphylactoid Reaction but Not Anaphylaxis

(2014) Yan-Ni Mi et al.   PLoS One

Epidemiological study (2006–2012) on the poisoning of small animals by human and veterinary drugs

(2014) F. Caloni et al.   VETERINARY RECORD

Xylitol

(2013) Michael E. Peterson   Topics in Companion Animal Medicine

Emergency Management and Treatment of the Poisoned Small Animal Patient

(2013) Justine A. Lee   VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE

Xylitol poisoning of dogs is associated with increased glycogenolysis, coagulopathy, and oxidative stress

(2013) Zhaofei Xia et al.   TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY

Complement activation associated with polysorbate 80 in beagle dogs

(2012) Shidong Qiu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Evaluation of propofol containing 2% benzyl alcohol preservative in cats

(2012) Polly M Taylor et al.   JOURNAL OF FELINE MEDICINE AND SURGERY

Xylitol Toxicosis in Dogs

(2012) Lisa A. Murphy et al.   VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE

Reactive Impurities in Excipients: Profiling, Identification and Mitigation of Drug–Excipient Incompatibility

(2011) Yongmei Wu et al.   AAPS PHARMSCITECH

Propylene glycol intoxication in a dog

(2011) Melissa A. Claus et al.   JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE

Treatment of accidental ethanol intoxication with hemodialysis in a dog

(2011) Lisa A. Keno et al.   JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE

Interactive Effect of Sodium Bentonite with Pigments on Performance and Egg Quality of Laying Hens

(2010) H. Hashemipou et al.   Journal of Animal and Veterinary Advances

Xylitol toxicity in dogs

(2010) A. Campbell et al.   VETERINARY RECORD

Single-dose pharmacokinetics and genotoxicity of metronidazole in cats

(2009) Ivana Sekis et al.   JOURNAL OF FELINE MEDICINE AND SURGERY

Experimental acute toxicity of xylitol in dogs

(2009) Z. XIA et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Quantifying the ‘hidden’ lactose in drugs used for the treatment of gastrointestinal conditions

(2008) P. EADALA et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Suspected primary lactose intolerance in neonatal foals

(2008) V. L. H. Roberts et al.   EQUINE VETERINARY EDUCATION

Lactose and lactose derivatives as bioactive ingredients in human nutrition

(2007) Gertjan Schaafsma   INTERNATIONAL DAIRY JOURNAL