Simplein vitromodels can predict pulmonary toxicity of silver nanoparticles

A newly developed in vitro model of the human epithelial airway barrier to study the toxic potential of nanoparticles

(2016) Barbara Rothen-Rutishauser   ALTEX-Alternatives to Animal Experimentation

Use of Synchrotron Radiation-Analytical Techniques To Reveal Chemical Origin of Silver-Nanoparticle Cytotoxicity

(2015) Liming Wang et al.   ACS Nano

Progress and future of in vitro models to study translocation of nanoparticles

(2015) Hedwig M. Braakhuis et al.   ARCHIVES OF TOXICOLOGY

A practical approach to determine dose metrics for nanomaterials

(2015) Christiaan J.E. Delmaar et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Identification of the appropriate dose metric for pulmonary inflammation of silver nanoparticles in an inhalation toxicity study

(2015) Hedwig M. Braakhuis et al.   Nanotoxicology

The development and function of lung-resident macrophages and dendritic cells

(2015) Manfred Kopf et al.   NATURE IMMUNOLOGY

Toxicity assessment of aggregated/agglomerated cerium oxide nanoparticles in an in vitro 3D airway model: The influence of mucociliary clearance

(2015) C. Frieke Kuper et al.   TOXICOLOGY IN VITRO

Development of an in vitro model of human bronchial epithelial barrier to study nanoparticle translocation

(2015) Isabelle George et al.   TOXICOLOGY IN VITRO

Size-Controlled Dissolution of Silver Nanoparticles at Neutral and Acidic pH Conditions: Kinetics and Size Changes

(2014) Tanya S. Peretyazhko et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity

(2014) Kristin Westphalen et al.   NATURE

Is the toxic potential of nanosilver dependent on its size?

(2014) Anna Huk et al.   Particle and Fibre Toxicology

Cytotoxic Potential of Silver Nanoparticles

(2014) Tianlu Zhang et al.   YONSEI MEDICAL JOURNAL

PVP-coated, negatively charged silver nanoparticles: A multi-center study of their physicochemical characteristics, cell culture and in vivo experiments

(2014) Sebastian Ahlberg et al.   Beilstein Journal of Nanotechnology

Carbohydrate functionalization of silver nanoparticles modulates cytotoxicity and cellular uptake

(2014) David C Kennedy et al.   JOURNAL OF NANOBIOTECHNOLOGY

The Stability of Silver Nanoparticles in a Model of Pulmonary Surfactant

(2013) Bey Fen Leo et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Comparative hazard identification of nano- and micro-sized cerium oxide particles based on 28-day inhalation studies in rats

(2013) Ilse Gosens et al.   Nanotoxicology

Comparative inhalation toxicity of multi-wall carbon nanotubes, graphene, graphite nanoplatelets and low surface carbon black

(2013) Lan Ma-Hock et al.   Particle and Fibre Toxicology

Multiwall Carbon Nanotubes Mediate Macrophage Activation and Promote Pulmonary Fibrosis Through TGF-β/Smad Signaling Pathway

(2013) Peng Wang et al.   Small

Toxicity of Silver Nanoparticles in Macrophages

(2013) Anna Pratsinis et al.   Small

Use of Coated Silver Nanoparticles to Understand the Relationship of Particle Dissolution and Bioavailability to Cell and Lung Toxicological Potential

(2013) Xiang Wang et al.   Small

The Biologically Effective Dose in Inhalation Nanotoxicology

(2012) Ken Donaldson et al.   ACCOUNTS OF CHEMICAL RESEARCH

Aquatic toxicity of nanosilver colloids to different trophic organisms: Contributions of particles and free silver ion

(2012) Zhuang Wang et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Assessing the relevance of in vitro studies in nanotoxicology by examining correlations between in vitro and in vivo data

(2012) Xianglu Han et al.   TOXICOLOGY

Measuring silver nanoparticle dissolution in complex biological and environmental matrices using UV–visible absorbance

(2011) Justin M. Zook et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles

(2011) Margriet V.D.Z. Park et al.   BIOMATERIALS

Size-Controlled Dissolution of Organic-Coated Silver Nanoparticles

(2011) Rui Ma et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Controlled Evaluation of Silver Nanoparticle Dissolution Using Atomic Force Microscopy

(2011) Ronald D. Kent et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Pulmonary toxicity of inhaled nanoscale and fine zinc oxide particles: Mass and surface area as an exposure metric

(2011) Meng Ho et al.   INHALATION TOXICOLOGY

Inflammatory and cytotoxic responses of an alveolar-capillary coculture model to silica nanoparticles: Comparison with conventional monocultures

(2011) Jennifer Kasper et al.   Particle and Fibre Toxicology

Potential of coculture in vitro models to study inflammatory and sensitizing effects of particles on the lung

(2011) Sebastian G. Klein et al.   TOXICOLOGY IN VITRO

Toxicity of silver nanoparticles—Nanoparticle or silver ion?

(2011) Christiane Beer et al.   TOXICOLOGY LETTERS

Uptake and intracellular distribution of silver nanoparticles in human mesenchymal stem cells

(2010) C. Greulich et al.   Acta Biomaterialia

Cerium oxide nanoparticle uptake kinetics from the gas-phase into lung cells in vitro is transport limited

(2010) David O. Raemy et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

An in vitro triple cell co-culture model with primary cells mimicking the human alveolar epithelial barrier

(2010) Andrea D. Lehmann et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Interactions between endothelial cells and epithelial cells in a combined cell model of airway mucosa: effects on tight junction permeability

(2010) Ferdousi Chowdhury et al.   EXPERIMENTAL LUNG RESEARCH

Silver nanoparticles in simulated biological media: a study of aggregation, sedimentation, and dissolution

(2010) Larissa V. Stebounova et al.   JOURNAL OF NANOPARTICLE RESEARCH

Impact of silver nanoparticles on human cells: Effect of particle size

(2010) Wei Liu et al.   Nanotoxicology

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Quantitative Evaluation of Cellular Uptake and Trafficking of Plain and Polyethylene Glycol-Coated Gold Nanoparticles

(2010) Christina Brandenberger et al.   Small

Acute inhalation toxicity of silver nanoparticles

(2010) Jae Hyuck Sung et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Poly(vinyl alcohol) nanoparticle stability in biological media and uptake in respiratory epithelial cell layers in vitro

(2009) M. Madlova et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Changing the dose metric for inhalation toxicity studies: Short-term study in rats with engineered aerosolized amorphous silica nanoparticles

(2009) Christie M. Sayes et al.   INHALATION TOXICOLOGY

Oxidative stress and inflammation response after nanoparticle exposure: differences between human lung cell monocultures and an advanced three-dimensional model of the human epithelial airways

(2009) L. Muller et al.   Journal of the Royal Society Interface

Subchronic 13-Week Inhalation Exposure of Rats to Multiwalled Carbon Nanotubes: Toxic Effects Are Determined by Density of Agglomerate Structures, Not Fibrillar Structures

(2009) Jürgen Pauluhn   TOXICOLOGICAL SCIENCES

In vitro developmental toxicity test detects inhibition of stem cell differentiation by silica nanoparticles

(2009) Margriet V.D.Z. Park et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Co-cultures of multiple cell types mimic pulmonary cell communication in response to urban PM10

(2008) E. Alfaro-Moreno et al.   EUROPEAN RESPIRATORY JOURNAL

Subchronic Inhalation Toxicity of Silver Nanoparticles

(2008) Jae Hyuck Sung et al.   TOXICOLOGICAL SCIENCES