A critical role of retinoic acid concentration for the induction of a fully human-like atrial action potential phenotype in hiPSC-CM

PITX2 Knockout Induces Key Findings of Electrical Remodeling as Seen in Persistent Atrial Fibrillation

(2023) Carl Schulz et al.   Circulation-Arrhythmia and Electrophysiology

Quantification of All-Trans Retinoic Acid by Liquid Chromatography–Tandem Mass Spectrometry and Association with Lipid Profile in Patients with Type 2 Diabetes

(2021) Jakob Morgenstern et al.   Metabolites

Patch-Clamp Recordings of Action Potentials From Human Atrial Myocytes: Optimization Through Dynamic Clamp

(2021) Arie O. Verkerk et al.   Frontiers in Pharmacology

High-Throughput Drug Screening System Based on Human Induced Pluripotent Stem Cell-Derived Atrial Myocytes ∼ A Novel Platform to Detect Cardiac Toxicity for Atrial Arrhythmias

(2021) Yayoi Honda et al.   Frontiers in Pharmacology

Human Atrial Cardiac Microtissues for Chamber-Specific Arrhythmic Risk Assessment

(2021) Arvin H. Soepriatna et al.   Cellular and Molecular Bioengineering

Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes

(2020) Idit Goldfracht et al.   Nature Communications

Ca2+ currents in cardiomyocytes: How to improve interpretation of patch clamp data?

(2020) Djemail Ismaili et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Ultrarapid Delayed Rectifier K+ Channelopathies in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

(2020) Sarah Hilderink et al.   Frontiers in Cell and Developmental Biology

Drug screening platform using human induced pluripotent stem cell‐derived atrial cardiomyocytes and optical mapping

(2020) Marvin G. Gunawan et al.   Stem Cells Translational Medicine

Human Induced Pluripotent Stem Cell–Derived Engineered Heart Tissue as a Sensitive Test System for QT Prolongation and Arrhythmic Triggers

(2018) Marc D. Lemoine et al.   Circulation-Arrhythmia and Electrophysiology

Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes

(2018) András Horváth et al.   Stem Cell Reports

Electrophysiologic Characterization of Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Atrial Cardiomyocytes

(2018) Mariana Argenziano et al.   Stem Cell Reports

Atrial-like Engineered Heart Tissue: An In Vitro Model of the Human Atrium

(2018) Marta Lemme et al.   Stem Cell Reports

Differentiation of cardiomyocytes and generation of human engineered heart tissue

(2017) Kaja Breckwoldt et al.   Nature Protocols

Chemical-defined and albumin-free generation of human atrial and ventricular myocytes from human pluripotent stem cells

(2017) Fei Pei et al.   Stem Cell Research

Modeling Atrial Fibrillation using Human Embryonic Stem Cell-Derived Atrial Tissue

(2017) Zachary Laksman et al.   Scientific Reports

The positive frequency-dependent electrophysiological effects of the IKur inhibitor XEN-D0103 are desirable for the treatment of atrial fibrillation

(2016) John Ford et al.   HEART RHYTHM

Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology

(2015) H. D. Devalla et al.   EMBO Molecular Medicine

Effects of IKur blocker MK-0448 on human right atrial action potentials from patients in sinus rhythm and in permanent atrial fibrillation

(2014) Simone Loose et al.   Frontiers in Pharmacology

The new antiarrhythmic drug vernakalant: ex vivo study of human atrial tissue from sinus rhythm and chronic atrial fibrillation

(2013) Erich Wettwer et al.   CARDIOVASCULAR RESEARCH

Human Electrophysiological and Pharmacological Properties of XEN-D0101

(2013) John Ford et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Ultra-rapid delayed rectifier channels: molecular basis and therapeutic implications

(2011) U. Ravens et al.   CARDIOVASCULAR RESEARCH

Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals

(2010) Qiangzhe Zhang et al.   CELL RESEARCH

Development of a Drug Screening Platform Based on Engineered Heart Tissue

(2010) Arne Hansen et al.   CIRCULATION RESEARCH

Pathology-specific effects of the IKur/Ito/IK,ACh blocker AVE0118 on ion channels in human chronic atrial fibrillation

(2008) T Christ et al.   BRITISH JOURNAL OF PHARMACOLOGY