Dupilumab Efficacy in Patients with Type 2 Asthma with and without Elevated Blood Neutrophils

Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program

(2021) Annette T Hastie et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Baseline sputum eosinophil+neutrophil subgroups’ clinical characteristics and longitudinal trajectories for NHLBI Severe Asthma Research Program (SARP 3) Cohort

(2020) A.T. Hastie et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma and fixed airflow obstruction: Long‐term trajectories suggest distinct endotypes

(2020) Benjamin M Smith et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Longitudinal outcomes of severe asthma: real-world evidence of multidimensional analyses

(2020) Youngsoo Lee et al.   Journal of Allergy and Clinical Immunology-In Practice

Severe Adult Asthmas: Integrating Clinical Features, Biology and Therapeutics to Improve Outcomes

(2020) Sally E. Wenzel   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level

(2019) Stephen C. Lazarus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phenotypes and endotypes of adult asthma: Moving toward precision medicine

(2019) Ravdeep Kaur et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Investigation of the relationship between IL-6 and type 2 biomarkers in patients with severe asthma

(2019) Xingnan Li et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The regulatory roles of neutrophils in adaptive immunity

(2019) Yang Li et al.   Cell Communication and Signaling

Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma

(2018) Mario Castro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neutrophil: A Cell with Many Roles in Inflammation or Several Cell Types?

(2018) Carlos Rosales   Frontiers in Physiology

Neutrophilic Inflammation in Asthma and Association with Disease Severity

(2017) Anuradha Ray et al.   TRENDS IN IMMUNOLOGY

Comorbidities and elevated IL-6 associate with negative outcome in adult-onset asthma

(2016) Pinja Ilmarinen et al.   EUROPEAN RESPIRATORY JOURNAL

The role of neutrophils in inflammation resolution

(2016) Hefin R. Jones et al.   SEMINARS IN IMMUNOLOGY

Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts

(2016) Michael C Peters et al.   Lancet Respiratory Medicine

Efficacy and safety of a CXCR2 antagonist, AZD5069, in patients with uncontrolled persistent asthma: a randomised, double-blind, placebo-controlled trial

(2016) Paul M O'Byrne et al.   Lancet Respiratory Medicine

Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data

(2014) Wei Wu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes

(2014) L. E. Macdonald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice

(2014) A. J. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis

(2013) Wendy C. Moore et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Systemic Inflammation Is Associated with Differential Gene Expression and Airway Neutrophilia in Asthma

(2013) Juan-juan Fu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

The Neutrophilic Inflammatory Phenotype Is Associated With Systemic Inflammation in Asthma

(2012) Lisa G. Wood et al.   CHEST

Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes

(2010) Annette T. Hastie et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Identification of Asthma Phenotypes Using Cluster Analysis in the Severe Asthma Research Program

(2009) Wendy C. Moore et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE