α2-Macroglobulin Promotes Chondrocyte Proliferation and Cartilage Matrix Synthesis via Inducing PCNA

A2M inhibits inflammatory mediators of chondrocytes by blocking IL‐1β/NF‐κB pathway

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Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repair capacity

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Early supplemental α2-macroglobulin attenuates cartilage and bone damage by inhibiting inflammation in collagen II-induced arthritis model

(2019) Shengchun Li et al.   International Journal of Rheumatic Diseases

Osteoarthritis

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Osteoarthritis

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Effects of the Mycotoxin Nivalenol on Bovine Articular Chondrocyte Metabolism In Vitro

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Identification of α2-Macroglobulin as a Master Inhibitor of Cartilage-Degrading Factors That Attenuates the Progression of Posttraumatic Osteoarthritis

(2014) Shaowei Wang et al.   Arthritis & Rheumatology

Is cartilage sGAG content related to early changes in cartilage disease? Implications for interpretation of dGEMRIC

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Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage

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Advanced glycation end products cause collagen II reduction by activating Janus kinase/signal transducer and activator of transcription 3 pathway in porcine chondrocytes

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Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

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Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin

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