Article
Chemistry, Multidisciplinary
Prabhpreet Singh, Andreas Hirsch
Summary: In this study, a 2nd generation dendron based on putrescine and bearing oligocarboxylic acids was synthesized and characterized. The hydrophilic groups were protected with tert-butyl groups, and the water solubility was enhanced through acidic deprotection.
Article
Chemistry, Organic
Costanza Vanni, Francesca Cardona, Francesca Clemente, Amelia Morrone, Martina Raudino, Moira Ambrosi, Pierandrea Lo Nostro, Camilla Matassini
Summary: Pharmacological chaperones are considered as an emerging therapy for Gaucher Disease. In this study, novel N-alkylated iminosugars were synthesized and characterized to investigate their biological activity. The results suggest that the C12 N-alkylated iminosugar 10 exerts its biological activity in the monomeric state.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Paula B. Chamorro, Fatima Aparicio, Raquel Chamorro, Nerea Bilbao, Santiago Casado, David Gonzalez-Rodriguez
Summary: The study found that dinucleobase amphiphilic monomers can self-assemble into helical nanotubes under different conditions, but may undergo different reactions when experimental conditions are changed, including disassembly, chiral reorganization or morphological restructuring.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Nanoscience & Nanotechnology
Ankita Kumari, Ipsita Pani, Mohammad Umer Lone, Aditi Aggarwal, Santanu Kumar Pal, Raj Kumar Roy
Summary: Due to simple synthetic strategies, randomly functionalized amphiphilic polymers have become highly researched. Recent studies have shown that these polymers can self-assemble into various nanostructures, similar to amphiphilic block copolymers. The study explored the self-assembly behavior of randomly functionalized hyperbranched polymers and their linear analogues in solution and at the liquid crystal-water interfaces. Regardless of their architecture, the designed amphiphiles formed spherical nanoaggregates in solution and influenced the ordering transitions of liquid crystal molecules at the liquid crystal-water interface. However, the linear analogues required 10 times less amphiphiles compared to the hyperbranched polymers to achieve the same ordering transition of liquid crystal molecules. Additionally, only the linear analogues responded to biorecognition events, which can be attributed to both of the aforementioned differences.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Ruslan R. Kashapov, Yuliya S. Razuvayeva, Svetlana S. Lukashenko, Syumbelya K. Amerhanova, Anna P. Lyubina, Alexandra D. Voloshina, Victor V. Syakaev, Vadim V. Salnikov, Lucia Y. Zakharova
Summary: The combined method of photodynamic therapy and chemotherapy for treating malignant neoplasms shows great promise. This study investigates the properties of a supramolecular system based on TSPP and LaSurf in an aqueous medium. The complexes can assemble into nanostructures capable of binding anticancer drugs and their stability and drug binding ability can be controlled by adjusting the molar ratio and concentration of the components.
Article
Polymer Science
Sayun Myung, Gwang Mo Kim, Hyeongju Noh, Ho-Joong Kim, Si Kyung Yang
Summary: The synthesis of stimuli-responsive amphiphilic dendrimers composed of hydrophobic octadecyl groups linked to hydrophilic polylysine dendrons through disulfide linkage is reported. These dendrimers can form spherical micelles that disassemble in the presence of glutathione, serving as key building blocks for generating stimuli-responsive supramolecular architectures.
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2021)
Article
Chemistry, Multidisciplinary
Yujia Wang, Wenjie Song, Lijun Bao, Junwu Wei, Yangyang Qian, Yunmei Bi
Summary: We report the synthesis and characterization of enzyme and pH dual responsive linear-dendritic block copolymers (LDBCs) for drug delivery applications. The LDBCs are capable of self-assembling into nanomicelles, which can be disassembled upon the presence of enzyme or changes in pH to release the encapsulated drugs. The release rates can be controlled by changing the generation of dendrons.
Article
Polymer Science
Cheng Deng, Hai Yang, Simin Liu, Zhiyong Zhao
Summary: In this study, two types of DNA-dendrimer amphiphiles were successfully constructed, including the G-quadruplex-dendrimer hybrid (G20-Den) and single-stranded DNA-dendrimer hybrid (D20-Den). Both of them self-assembled into nanofibers with a length of several micrometers in MES buffer, and the diameter of G20-Den nanofibers was smaller than that of D20-Den nanofibers due to the compact stacking of G-quadruplex formed in G20-Den hybrids. The catalytic properties of G20-Den nanofiber/hemin, as well as the single-stranded G20/hemin system, were investigated, and they exhibited higher catalytic peroxidation activity than D20-Den nanofiber/hemin. Furthermore, the recycle of these nanofibers can be simply achieved through simple ultrafiltration.
Article
Chemistry, Multidisciplinary
Naohiro Kameta, Masaki Kogiso
Summary: The study found that different regioisomeric dihydroxy naphthalenes can lead to the formation of nanotubes or nanofibers with different structures when complexed with pyridine-based amphiphiles, and the inner diameter is strongly correlated with the aggregation states. These findings are crucial for fine-tuning the inner diameters of supramolecular nanotubes and controlling the aggregation states of functional aromatic molecules.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Fengjuan Xie, Yingying Lin, Asa Andersson, Irina Vetter, Liang Zhao, JingJing Wan
Summary: In this study, alkylated lysine-dendron oxytocin amphiphiles (ALOAs) 1G-OTK and 2G-OTK were designed and self-assembled into spherical nanoparticles and nanostrips, respectively, showing superior stability compared to native oxytocin. Similar trends in functional activity were observed between ALOAs and native oxytocin for human oxytocin receptor. This work may inspire the development of peptide drugs for clinical applications.
CHEMICAL COMMUNICATIONS
(2023)
Article
Biophysics
Barbara Claro, Antonio Peon, Eva Gonzalez-Freire, Erik Goormaghtigh, Manuel Amorin, Juan R. Granja, Rebeca Garcia-Fandino, Margarida Bastos
Summary: Antimicrobial D,L-alpha-cyclic peptides have shown to form complex macromolecular assemblies in the presence of membranes, depending on the negatively charged content of the membrane and lipid/peptide ratio. Experimental techniques and simulations suggest that CPs can self-assemble at the lipid surface into nanotubes or micellar aggregates, revealing possible mechanisms of action involving membrane segregation or disintegration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Florian Mahler, Annette Meister, Carolyn Vargas, Gregory Durand, Sandro Keller
Summary: The use of specific amphiphilic molecules can directly assemble lipids and membrane proteins to form native nanodiscs, rather than mixed micelles. Detailed investigation into the lipid bilayer integrity and membrane protein activity in these nanodiscs reveals gentle effects.
Article
Chemistry, Multidisciplinary
Manuel A. Martinez, Elisa E. Greciano, Jorge Cuellar, Jose M. Valpuesta, Luis Sanchez
Summary: In this study, a highly emissive amphiphilic N-annulated PBI 1 decorated with oligo ethylene glycol (OEG) side chains was synthesized. Compound 1 self-assembles in water to form globular aggregates, demonstrating good solubility and stability in aqueous media. The UV-Vis spectra and solvent denaturation experiments provided insights into the self-assembly process and stability of compound 1 in different solvents.
Article
Chemistry, Multidisciplinary
Xiaohui Wu, Feihe Ma, Bin-Bin Pan, Yanli Zhang, Lin Zhu, Fei Deng, Linlin Xu, Yu Zhao, Xu Yin, Haihong Niu, Xun-Cheng Su, Linqi Shi
Summary: The development of a nanochaperone (α-S-nChap) tailored for alpha-synuclein regulation shows promise in preventing neurodegenerative diseases by controlling protein misassembly. This nanochaperone has the ability to specifically recognize, capture, and stabilize the monomeric form of alpha-synuclein, ultimately impeding its oligomerization. The strategy of using nanochaperones to regulate aberrant protein assembly provides important insights into potential therapeutic interventions for Parkinson's disease.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Physical
Niki Baccile, Alexandre Poirier, Chloe Seyrig, Patrick Le Griel, Javier Perez, Daniel Hermida-Merino, Petra Pernot, Sophie L. K. W. Roelants, Wim Soetaert
Summary: This study demonstrates the chameleonic self-assembly behavior of a low molecular weight amphiphile, which can form various phases depending on pH, temperature, and counterions. This compound shows rich phase behavior and has potential applications in biocompatible and biodegradable self-assembled materials.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Kwaku Twum, Sanaz Nadimi, Frank Boateng Osei, Rakesh Puttreddy, Yvonne Bessem Ojong, John J. Hayward, Kari Rissanen, John F. Trant, Ngong Kodiah Beyeh
Summary: In this study, the formation of a three-component halogen-bonded ternary assembly in a protic polar solvent system is achieved by utilizing the binding of fused aromatic N-heterocycles in an open resorcinarene cavity to template the assembly. This approach overcomes the challenges posed by the overwhelming quantity of competing solvent.
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Article
Pharmacology & Pharmacy
Jiangtao Wu, Xiangbin Du, Dongmei Zhang, Jicheng Cui, Xiaoxia Zhang, Xine Duan, John F. Trant, Yingqi Li
Summary: This study developed a dual-gated folate-functionalized nanodiamond drug delivery system that selectively delivers drugs to cancer cells, reducing side effects. The system has activatable fluorescence and cytotoxicity and releases drugs through high levels of glutathione.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Chemistry, Medicinal
Zakir Ali, Ambika Goyal, Ayush Jhunjhunwala, Abhijit Mitra, John F. Trant, Purshotam Sharma
Summary: This study analyzed different stacking geometries in RNA crystal structures and identified 1,735,481 stacking contacts. It found preferential occurrences of specific stacking arrangements in certain regions of RNA architectures. Quantum chemical calculations showed that 88 of the contacts possessed intrinsically stable stacking geometries.
JOURNAL OF CHEMICAL INFORMATION AND MODELING
(2023)
Article
Polymer Science
Esra Aydinlioglu, Mona Abdelghani, Gaelle Le Fer, Jan C. M. van Hest, Olivier Sandre, Sebastien Lecommandoux
Summary: Two pairs of oppositely charged PEO-b-poly(amino acid) copolymers were synthesized and self-assembled into stable polyion complexes (PICsomes) with high potential as biocompatible nanocarriers for RNA interference. These PICsomes exhibited good stability even in high salinity media due to hydrophobic interactions between the phenylalanine residues. They successfully loaded small interfering RNA (siRNA) and showed minimal cell cytotoxicity while demonstrating superior gene silencing efficacy compared to free siRNA and a standard lipofectamine-siRNA complex.
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2023)
Article
Materials Science, Biomaterials
Xudong Cai, Bo Fan, San H. Thang, Calum J. Drummond, Nhiem Tran, Jiali Zhai
Summary: Responsive nanoparticle delivery systems have potential for reducing off-target side effects in chemotherapeutic treatment. In this study, lipid-based cubosomes loaded with paclitaxel were formulated and stabilized by novel amphiphilic block copolymers containing pH-responsive and/or hydrogen peroxide-responsive blocks. The cubosomes demonstrated high encapsulation efficiency and controlled release of the drug in response to pH and H2O2 changes. In vitro cytotoxicity and cell uptake studies showed that the cubosomes had higher toxicity and cell internalization efficiency compared to free paclitaxel and cubosomes stabilized by non-responsive block copolymers. The results highlight the potential of responsive block copolymers in stabilizing lipid cubosomes and enhancing drug release and cellular uptake.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Chemistry, Multidisciplinary
Clemence Schvartzman, Hang Zhao, Emmanuel Ibarboure, Vusala Ibrahimova, Elisabeth Garanger, Sebastien Lecommandoux
Summary: In response to osmotic stress, cells release excess water to avoid bursting and death. By encapsulating functional elastin-like polypeptide (ELP) biomacromolecular conjugates into lipid vesicles using a microfluidic system, researchers mimic the formation of membraneless organelles induced by water expulsion. The local concentration increase and decrease in cloud point temperature (T-cp) of ELP bioconjugates due to hypertonic shock lead to the formation of coacervates, which mimic cellular stress-induced organelle assemblies. This dynamic response to osmotic stress can increase the local concentration and accelerate the enzymatic reaction.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Physical
Mehdi Noura, Maryam Kosar, Abbas Rahdar, John F. Trant
Summary: Hydrogen is a clean energy storage method in a post-fossil fuel era. Physical adsorption on graphene and nanotubes provides an efficient approach for hydrogen storage, and magnesium-doped boron nitride nanotubes hold promise in this area. Theoretical calculations show that highly magnesium-doped boron nitride nanotubes can achieve high hydrogen storage capacity, surpassing the targets set by the US Department of Energy.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Pharmacology & Pharmacy
Anouk Martin, Pierre Lalanne, Amelie Weber-Vax, Angela Mutschler, Sebastien Lecommandoux
Summary: The self-assembly of PEG-b-PTMC copolymers into vesicles, also known as polymersomes, was evaluated using microfluidic systems. Two microfluidic chips with different flow regimes were used to investigate the impact of process conditions on vesicle formation. A solvent exchange approach was developed to allow direct use of the polymersomes in biological evaluation. The size of the polymersomes was influenced by the total flow rate and copolymer concentration, but not by the organic/aqueous solvent ratio.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Multidisciplinary Sciences
Christopher Jonkergouw, Ngong Kodiah Beyeh, Ekaterina Osmekhina, Katarzyna Leskinen, S. Maryamdokht Taimoory, Dmitrii Fedorov, Eduardo Anaya-Plaza, Mauri A. Kostiainen, John F. Trant, Robin H. A. Ras, Paivi Saavalainen, Markus B. Linder
Summary: A water-soluble synthetic macrocycle, Pillar[5]arene, has been identified to bind to key virulence factors in Gram-negative pathogens, suppressing toxins and biofilms and enhancing the efficacy of standard antibiotics. It evades existing antibiotic resistance mechanisms and shows promise as a dual-acting anti-virulence treatment against Top Priority pathogens.
NATURE COMMUNICATIONS
(2023)
Article
Pharmacology & Pharmacy
Sarfraz Ahmad, Muhammad Usman Mirza, John F. Trant
Summary: Peptide-based therapeutics are gaining attention in biomedicine due to their high specificity and low toxicity. This study provides a dataset of all di-, tri-, tetra-, and penta-peptide sequences for screening against protein targets. Access to this dataset will accelerate small peptide screening workflows and encourage their use in drug discovery campaigns.
JOURNAL OF PHARMACEUTICAL ANALYSIS
(2023)
Article
Biochemistry & Molecular Biology
Chloe Grazon, Elisabeth Garanger, Pierre Lalanne, Emmanuel Ibarboure, James E. Galagan, Mark W. Grinstaff, Sebastien Lecommandoux
Summary: Polymeric micelles based on natural diblocks, such as elastin-like polypeptide (ELP) and oligonucleotide (ON), have advantageous properties in terms of molecular recognition, biocompatibility, and biodegradability. This study reports a straightforward synthesis of ON-b-ELP diblock bioconjugates through copper-catalyzed azide-alkyne cycloaddition. The resulting micelles self-assemble above their critical micelle temperature (CMT) to form stable structures, and they retain their stability and temperature sensitivity when binding with proteins.
Article
Chemistry, Physical
Mehdi Shakourian-Fard, Hamid Reza Ghenaatian, Ganesh Kamath, Farouq S. Mjalli, John F. Trant
Summary: Density functional theory (DFT) calculations were used to evaluate the intermolecular interactions between deep eutectic solvents (DESs) and boron nitride nanotubes. DESs were found to spontaneously adsorb onto the nanotubes through van der Waals interactions and charge transfer from the DESs to the nanotubes. Nanotubes with a boron vacancy exhibited higher affinity. The adsorption of DESs onto boron nitride was stronger than onto carbon nanotubes. DESs incorporating benzoic acid showed stronger interactions with the surfaces, possibly due to 7C-7C interactions that are not available to other DESs.
CHEMICAL PHYSICS LETTERS
(2023)
Article
Pharmacology & Pharmacy
Jicheng Cui, Wenjing Zhao, Jiangtao Wu, Dongmei Zhang, Longguang Liu, Hui Qiao, Zeyu Yan, Yuejun Fu, John F. Trant, Yingqi Li
Summary: Combination chemotherapy using mitoxantrone and doxorubicin loaded onto a nanodiamond scaffold showed enhanced synergistic effect, slow and effective drug release, and targeted delivery. This nanodrug exhibited excellent stability, entered cells through specific pathways, and primarily remained within the lysosomes. It demonstrated strong tumor growth suppression with reduced toxic side effects in animal experiments.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Review
Chemistry, Organic
Abhinandan Banerjee, John J. Hayward, John F. Trant
Summary: THC and CBD, the major cannabinoids, face challenges in their incorporation into clinical and nutraceutical preparations due to limited bioavailability, low water solubility, and variable pharmacokinetic profiles. Derivatization offers potential solutions to these issues by providing labile pro-drugs with enhanced bioavailability or interesting pharmacological properties. This review explores advanced derivatization strategies for the major cannabinoids, using pure phytocannabinoids as starting materials to produce cannabinoid pro-drugs or novel pharmacoactive materials.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Saira Naseem, Samra Khan, Safdar Hussain, Muhammad Usman Mirza, Muhammad Ashraf, Zahid Shafiq, John F. Trant
Summary: This study describes the design and synthesis of xanthene-based thiosemicarbazones that show effective inhibition of acetylcholinesterase (AChE) associated with Alzheimer's Disease. These compounds demonstrate selectivity for AChE over butyrylcholinesterase (BChE) and can serve as preliminary hits for further development. Molecular docking analysis reveals the importance of the xanthene scaffold for AChE binding and the aryl R2 moiety for BChE interactions. Some compounds also show dual enzyme targeting, suggesting their potential as monotherapies for cholinesterase-related neurodegenerative diseases like Alzheimer's Disease.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Chemistry, Multidisciplinary
Laetitia Bardet, Herve Roussel, Stefano Saroglia, Masoud Akbari, David Munoz-Rojas, Carmen Jimenez, Aurore Denneulin, Daniel Bellet
Summary: The thermal instability of silver nanowires leads to increased electrical resistance in AgNW networks. Understanding the relationship between structural and electrical properties of AgNW networks is crucial for their integration as transparent electrodes in flexible optoelectronics. In situ X-ray diffraction measurements were used to study the crystallographic evolution of Ag-specific Bragg peaks during thermal ramping, revealing differences in thermal and structural transitions between bare and SnO2-coated AgNW networks.
Article
Chemistry, Multidisciplinary
Nathalia Cancino-Fuentes, Arnau Manasanch, Joana Covelo, Alex Suarez-Perez, Enrique Fernandez, Stratis Matsoukis, Christoph Guger, Xavi Illa, Anton Guimera-Brunet, Maria V. Sanchez-Vives
Summary: This study provides a comprehensive characterization of graphene-based solution-gated field-effect transistors (gSGFETs) for brain recordings, highlighting their potential clinical applications.
Article
Chemistry, Multidisciplinary
Sikandar Aftab, Hailiang Liu, Dhanasekaran Vikraman, Sajjad Hussain, Jungwon Kang, Abdullah A. Al-Kahtani
Summary: This study examines the effects of hybrid nanoparticles made of NiO@rGO and NiO@CNT on the active layers of polymer solar cells and X-ray photodetectors. The findings show that these hybrid nanoparticles can enhance the charge carrier capacities and exciton dissociation properties of the active layers. Among the tested configurations, the NiO@CNT device demonstrates superior performance in converting sunlight into electricity, and achieves the best sensitivity for X-ray detection.
Article
Chemistry, Multidisciplinary
Hyo Jung Shin, Seung Gyu Choi, Fengrui Qu, Min-Hee Yi, Choong-Hyun Lee, Sang Ryong Kim, Hyeong-Geug Kim, Jaewon Beom, Yoonyoung Yi, Do Kyung Kim, Eun-Hye Joe, Hee-Jung Song, Yonghyun Kim, Dong Woon Kim
Summary: This study investigates the role of SOX9 in reactive astrocytes following ischemic brain damage using a PLGA nanoparticle plasmid delivery system. The results demonstrate that PLGA nanoparticles can reduce ischemia-induced neurological deficits and infarct volume, providing a potential opportunity for stroke treatment.
Article
Chemistry, Multidisciplinary
Anurag Chaudhury, Koushik Debnath, Nikhil R. Jana, Jaydeep K. Basu
Summary: The study investigates the interaction between nanoparticles and cell membranes, and identifies key parameters, including charge, crowding, and membrane fluidity, that determine the adsorbed concentration and unbinding transition of nanoparticles.
Article
Chemistry, Multidisciplinary
Sina Sadeghi, Fazel Bateni, Taekhoon Kim, Dae Yong Son, Jeffrey A. Bennett, Negin Orouji, Venkat S. Punati, Christine Stark, Teagan D. Cerra, Rami Awad, Fernando Delgado-Licona, Jinge Xu, Nikolai Mukhin, Hannah Dickerson, Kristofer G. Reyes, Milad Abolhasani
Summary: In this study, an autonomous approach for the development of lead-free metal halide perovskite nanocrystals is presented, which integrates a modular microfluidic platform with machine learning-assisted synthesis modeling. This approach enables rapid and optimized synthesis of copper-based lead-free nanocrystals.
Article
Chemistry, Multidisciplinary
Zahir Abbas, Nissar Hussain, Surender Kumar, Shaikh M. Mobin
Summary: The rational construction of free-standing and flexible electrodes for electrochemical energy storage devices is an emerging research focus. In this study, a redox-active metal-organic framework (MOF) was prepared on carbon nanofibers using an in situ approach, resulting in a flexible electrode with high redox-active behavior and unique properties such as high flexibility and lightweight. The prepared electrode showed excellent cyclic retention and rate capability in supercapacitor applications. Additionally, it could be used as a freestanding electrode in flexible devices at different bending angles.
Article
Chemistry, Multidisciplinary
Lishan Zhang, Xiaoting Zhang, Hui Ran, Ze Chen, Yicheng Ye, Jiamiao Jiang, Ziwei Hu, Miral Azechi, Fei Peng, Hao Tian, Zhili Xu, Yingfeng Tu
Summary: Photodynamic therapy (PDT) is a promising local treatment modality in cancer therapy, but its therapeutic efficacy is restricted by ineffective delivery of photosensitizers and tumor hypoxia. In this study, a phototactic Chlorella-based near-infrared (NIR) driven green affording-oxygen microrobot system was developed for enhanced PDT. The system exhibited desirable phototaxis and continuous oxygen generation, leading to the inhibition of tumor growth in mice. This study demonstrates the potential of using a light-driven green affording-oxygen microrobot to enhance photodynamic therapy.
Article
Chemistry, Multidisciplinary
Yujin Li, Jing Xu, Xinqi Luo, Futing Wang, Zhong Dong, Ke-Jing Huang, Chengjie Hu, Mengyi Hou, Ren Cai
Summary: In this study, hollow heterostructured materials were constructed using an innovative template-engaged method as cathodes for zinc-ion batteries. The materials exhibited fast Zn2+ transport channels, improved electrical conductivity, and controlled volume expansion during cycling. The designed structure allowed for an admirable reversible capacity and high coulombic efficiency.
Article
Chemistry, Multidisciplinary
Paritosh Mahato, Shashi Shekhar, Rahul Yadav, Saptarshi Mukherjee
Summary: This study comprehensively elucidates the role of the core and electrostatic surface of metal nanoclusters in catalytic reduction reactions. The electrostatic surface dramatically modulates the reactivity of metal nanoclusters.
Article
Chemistry, Multidisciplinary
Pei Liu, Mengdi Liang, Zhengwei Liu, Haiyu Long, Han Cheng, Jiahe Su, Zhongbiao Tan, Xuewen He, Min Sun, Xiangqian Li, Shuai He
Summary: This study demonstrates a simple and environmentally-friendly method for the synthesis of zinc oxide nanozymes (ZnO NZs) using wasted hop extract (WHE). The WHE-ZnO NZs exhibit exceptional peroxidase-like activity and serve as effective catalysts for the oxidation of 3,3,5,5-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2). In addition, a straightforward colorimetric technique for detecting both H2O2 and glucose was developed using the WHE-ZnO NZs as peroxidase-like catalysts.
Article
Chemistry, Multidisciplinary
Hyunkyu Oh, Young Jun Lee, Eun Ji Kim, Jinseok Park, Hee-Eun Kim, Hyunsoo Lee, Hyunjoo Lee, Bumjoon J. Kim
Summary: Mesoporous carbon particles have unique structural properties that make them suitable as support materials for catalytic applications. This study investigates the impact of channel nanostructures on the catalytic activity of porous carbon particles (PCPs) by fabricating PCPs with controlled channel exposure on the carbon surface. The results show that PCPs with highly open channel nanostructures exhibit significantly higher catalytic activity compared to those with closed channel nanostructures.
Article
Chemistry, Multidisciplinary
Yunjie Lu, Zhaohui Li, Zewei Li, Shihao Zhou, Ning Zhang, Jianming Zhang, Lu Zong
Summary: A tough, long-lasting adhesive and highly conductive nanocomposite hydrogel (PACPH) was fabricated via the synergy of interfacial entanglement and adhesion group densification. PACPH possesses excellent mechanical properties, interfacial adhesion strength, and conductivity, making it a promising material for long-term monitoring of human activities and electrocardiogram signals.
Article
Chemistry, Multidisciplinary
Zichao Wei, Audrey Vandergriff, Chung-Hao Liu, Maham Liaqat, Mu-Ping Nieh, Yu Lei, Jie He
Summary: We have developed a simple method to prepare polymer-grafted plasmonic metal nanoparticles with pH-responsive surface-enhanced Raman scattering. By using pH-responsive polymers as ligands, the aggregation of nanoparticles can be controlled, leading to enhanced SERS. The pH-responsive polymer-grafted nanoparticles show high reproducibility and sensitivity in solution, providing a novel approach for SERS without the need for sample pre-concentration.
Article
Chemistry, Multidisciplinary
Melis Ozge Alas Colak, Ahmet Gungor, Merve Buldu Akturk, Emre Erdem, Rukan Genc
Summary: This research investigates the effect of functionalizing carbon dots with hydroxyl polymers on their performance as electrode materials in a supercapacitor. The results show that the functionalized carbon dots exhibit excellent electrochemical performance and improved stability.
