Article
Health Care Sciences & Services
Valentina Varalta, Paola Poiese, Serena Recchia, Barbara Montagnana, Cristina Fonte, Mirko Filippetti, Michele Tinazzi, Nicola Smania, Alessandro Picelli
Summary: This study investigated the effects of consecutive physiotherapy and cognitive rehabilitation on cognitive, motor, and psychological aspects in Parkinson's disease patients. Results showed that patients who received consecutive training performed better in functional mobility and memory tasks, supporting the hypothesis that consecutive physiotherapy plus cognitive rehabilitation may be more beneficial than physiotherapy alone.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Neurosciences
Alberto Cucca, Claudia Virginia Manara, Mauro Catalan, Marco Liccari, Lucia Antonutti, Tiziana Maria Isabella Lombardo, Valentina Cenacchi, Sophie Rangan, Serena Mingolo, Carmelo Crisafulli, Franca Dore, Mauro Murgia, Tiziano Agostini, Paolo Manganotti
Summary: Visual hallucinations are common symptoms of Parkinson's Disease, and are associated with impairments in perceptual processing and modulation. This study found that perceptual performance in PD patients is related to the presence of hallucinations, as well as abnormal top-down perceptual modulation.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Psychiatry
Shaynna N. Herrera, Vance Zemon, Nadine Revheim, Gail Silipo, James Gordon, Pamela D. Butler
Summary: Individuals with schizophrenia who exhibit deficits in visual contrast processing also show impairment in neurocognition and functional outcomes. This study found that contrast sensitivity, particularly to low spatial frequencies, is associated with cognitive function as a mediator for independent living capacity. Perceptual organization and memory-related domains were identified as key factors in mediating this relationship.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Article
Neurosciences
Tatiana Usnich, Bjoern Hauptmann, Henrike Hanssen, Jannik Prasuhn, Alexander Balck, Max Borsche, Vera Tadic, Annika Klee, Greta Noblejas-Sanchez, Eva-Juliane Vollstedt, Christine Klein, Norbert Brueggemann, Meike Kasten, EPIPARK Study Grp
Summary: Depressive symptoms in Parkinson's disease (PD) are multifactorial, including both dopaminergic deficit and chronic illness-related reactions. The prevalence and severity of depressive symptoms are similar between PD patients and disease controls (DC), though PD patients use antidepressants, especially Mirtazapine, more frequently. However, a significant proportion of patients in both groups with clinically significant depressive symptoms were not receiving medication. The diagnosis and treatment of depressive symptoms in both PD and DC should be improved.
NPJ PARKINSONS DISEASE
(2023)
Article
Neurosciences
Kishoree Sangarapillai, Benjamin M. Norman, Quincy J. Almeida
Summary: Falls are common and harmful for people with Parkinson's disease, with medication having limited effectiveness in reducing them. Exercise therapy can help reduce falls objectively, but improving both self-perceived and objective fall risk is important for enhancing overall quality of life in PD patients.
Article
Multidisciplinary Sciences
David Avraham, Yitzhak Yitzhaky
Summary: This study aimed to improve the restoration effect of retinal prostheses on vision for blind individuals using object isolation algorithm and image processing techniques. The results indicated an enhancement in perceived shape, contrast, and dynamic range of objects in the phosphene image.
Review
Medicine, General & Internal
Jianhua Liu, Jige Dong, Yaping Chen, Weidong Zhang, Shuai Tong, Jiangzhou Guo
Summary: This meta-analysis of 52 RCTs suggests that low vision rehabilitation has significant effects on improving vision-related QoL and visual functioning in visually impaired adults. However, compared to active comparators, no significant difference was found in health-related QoL and adaptation to vision loss.
Article
Ophthalmology
Filippos Vingopoulos, Itika Garg, Esther Lee Kim, Merina Thomas, Rebecca F. Silverman, Megan Kasetty, Zakariyya Y. Hassan, Gina Yu, Katherine Joltikov, Eun Young Choi, Ines Lains, Leo A. Kim, David N. Zacks, John B. Miller
Summary: The study revealed that contrast sensitivity is significantly reduced in CSCR and strongly correlates with subjective visual impairment. Different structural biomarkers are associated with contrast thresholds reductions at different spatial frequencies.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Clinical Neurology
Rocio Del Pino, Marian Acera, Ane Murueta-Goyena, Olaia Lucas-Jimenez, Natalia Ojeda, Naroa Ibarretxe-Bilbao, Javier Pena, Paula Reyero, Jesus Cortes, Beatriz Tijero, Marta Galdos, Juan Carlos Gomez-Esteban, Inigo Gabilondo
Summary: This study demonstrated a strong association between lower-level visual dysfunction and cognitive performance in Parkinson's disease, especially when cognitive tests are based on visual input. High and low-contrast visual acuity were significantly correlated with visual cognition in PD patients.
PARKINSONISM & RELATED DISORDERS
(2021)
Review
Behavioral Sciences
Marcella Montagnese, Miriam Vignando, Dominic Ffytche, Mitul A. Mehta
Summary: This meta-analysis investigated visual and cognitive impairments in Parkinson's Disease Psychosis (PDP) patients. The results showed that PD patients with visual hallucinations (PDVH) performed worse than those without hallucinations (PDnoVH) in various measures of cognition and visual processing, with executive functions, attention, episodic memory, and visual processing showing the greatest differences. This study highlights the need for a broader range of cognitive and processing domains to be considered in models of PDVH.
Article
Multidisciplinary Sciences
Joon Hyung Yeo, Seon Ha Bae, Seung Hyeun Lee, Kyoung Woo Kim, Nam Ju Moon
Summary: The study evaluated the efficacy of a wearable smartphone-based low vision aid in patients with visual impairment, showing significant improvements in visual function and positive impact on the quality of life in younger patients.
SCIENTIFIC REPORTS
(2022)
Article
Clinical Neurology
Naomi Hannaway, Angeliki Zarkali, Louise-Ann Leyland, Fion Bremner, Jennifer M. Nicholas, Siegfried K. Wagner, Matthew Roig, Pearse A. Keane, Ahmed Toosy, Jeremy Chataway, Rimona Sharon Weil
Summary: Visual dysfunction in Parkinson's disease predicts dementia and poor outcomes, while retinal thickness has less predictive power. This suggests that cortical structures play a role in the progression of Parkinson's dementia, and visual tests may be useful for stratification in clinical trials.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Article
Neurosciences
Chiara Capparini, Michelle P. S. To, Vincent M. Reid
Summary: Human infants are sensitive to social information in their visual world. A study measured 9-month-old infants' sensitivities to face-like configurations and found that infants' performance dropped beyond a certain eccentricity, indicating lower sensitivity to face-like stimuli far from the center of their visual field.
Article
Psychology, Clinical
Helene Verdoux, Clelia Quiles, Laura Bon, Isabelle Chereau-Boudet, Julien Dubreucq, Lucia Fiegi, Nathalie Guillard-Bouhet, Catherine Massoubre, Julien Plasse, Nicolas Franck
Summary: The study found that high-anticholinergic load is significantly associated with lower stage of recovery, poor mental well-being, poor self-rated medication adherence, and poorer delayed-episodic memory. Additionally, high-anticholinergic score is also related to faster completion time on tests exploring executive performance.
PSYCHOLOGICAL MEDICINE
(2021)
Review
Engineering, Biomedical
Susana Moleirinho, Andrew J. Whalen, Shelley Fried, John S. Pezaris
Summary: The development of visual prosthesis devices faces challenges in understanding factors such as phosphenes and how electrical patterns influence phosphenes generation. Research on synchronous and asynchronous electrical stimulation across multiple electrodes is crucial for creating a clinically successful prosthesis.
JOURNAL OF NEURAL ENGINEERING
(2021)