A computational framework for interspecies pharmacokinetics, exposure and toxicity assessment of gold nanoparticles

Nanomaterial Categorization for Assessing Risk Potential To Facilitate Regulatory Decision-Making

(2015) Hilary Godwin et al.   ACS Nano

Development and Application of a Multiroute Physiologically Based Pharmacokinetic Model for Oxytetracycline in Dogs and Humans

(2015) Zhoumeng Lin et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Predicting the impact of biocorona formation kinetics on interspecies extrapolations of nanoparticle biodistribution modeling

(2015) Faryad Darabi Sahneh et al.   Nanomedicine

Computational modeling in nanomedicine: prediction of multiple antibacterial profiles of nanoparticles using a quantitative structure–activity relationship perturbation model

(2015) Alejandro Speck-Planche et al.   Nanomedicine

In vivo integrity of polymer-coated gold nanoparticles

(2015) Wolfgang G. Kreyling et al.   Nature Nanotechnology

Biomedical applications of gold nanomaterials: opportunities and challenges

(2015) Abhilash Sasidharan et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Computational Tool for Risk Assessment of Nanomaterials: Novel QSTR-Perturbation Model for Simultaneous Prediction of Ecotoxicity and Cytotoxicity of Uncoated and Coated Nanoparticles under Multiple Experimental Conditions

(2014) Valeria V. Kleandrova et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Short- and long-term distribution and toxicity of gold nanoparticles in the rat after a single-dose intravenous administration

(2014) Sónia Fraga et al.   Nanomedicine-Nanotechnology Biology and Medicine

Using physiologically based pharmacokinetic (PBPK) modeling for dietary risk assessment of titanium dioxide (TiO2) nanoparticles

(2014) Gerald Bachler et al.   Nanotoxicology

Physiologically based pharmacokinetic modeling of polyethylene glycol-coated polyacrylamide nanoparticles in rats

(2014) Dingsheng Li et al.   Nanotoxicology

An integrated approach for the in vitro dosimetry of engineered nanomaterials

(2014) Joel M Cohen et al.   Particle and Fibre Toxicology

Species Extrapolation of Life-Stage Physiologically-Based Pharmacokinetic (PBPK) Models to Investigate the Developmental Toxicology of Ethanol Using In vitro to In vivo (IVIVE) Methods

(2014) Sheppard A. Martin et al.   TOXICOLOGICAL SCIENCES

Pharmacokinetics of metallic nanoparticles

(2014) Zhoumeng Lin et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Facing the Truth about Nanotechnology in Drug Delivery

(2013) Kinam Park   ACS Nano

Uptake of Engineered Gold Nanoparticles into Mammalian Cells

(2013) Lev A. Dykman et al.   CHEMICAL REVIEWS

Of mice, men and nanoparticle biocoronas: arein vitrotoin vivocorrelations and interspecies extrapolations realistic?

(2013) Jim E Riviere   Nanomedicine

Nano-SAR Development for Bioactivity of Nanoparticles with Considerations of Decision Boundaries

(2013) Rong Liu et al.   Small

Estimation of placental and lactational transfer and tissue distribution of atrazine and its main metabolites in rodent dams, fetuses, and neonates with physiologically based pharmacokinetic modeling

(2013) Zhoumeng Lin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Toxico-/biokinetics of nanomaterials

(2012) Robert Landsiedel et al.   ARCHIVES OF TOXICOLOGY

Development of screening assays for nanoparticle toxicity assessment in human blood: preliminary studies with charged Au nanoparticles

(2012) Sara A Love et al.   Nanomedicine

Factors Controlling Nanoparticle Pharmacokinetics: An Integrated Analysis and Perspective

(2011) S.M. Moghimi et al.   Annual Review of Pharmacology and Toxicology

Effect of surface coating on the biodistribution profile of gold nanoparticles in the rat

(2011) Tiago Morais et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Using nano-QSAR to predict the cytotoxicity of metal oxide nanoparticles

(2011) Tomasz Puzyn et al.   Nature Nanotechnology

Silica and titanium dioxide nanoparticles cause pregnancy complications in mice

(2011) Kohei Yamashita et al.   Nature Nanotechnology

Development and application of a physiologically based pharmacokinetic model for triadimefon and its metabolite triadimenol in rats and humans

(2011) Susan Ritger Crowell et al.   TOXICOLOGY LETTERS

Physiologically Based Pharmacokinetic Modeling of Nanoparticles

(2010) Mingguang Li et al.   ACS Nano

Biodistribution and toxicity of engineered gold nanoparticles: a review of in vitro and in vivo studies

(2010) Nikolai Khlebtsov et al.   CHEMICAL SOCIETY REVIEWS

Phase I and Pharmacokinetic Studies of CYT-6091, a Novel PEGylated Colloidal Gold-rhTNF Nanomedicine

(2010) S. K. Libutti et al.   CLINICAL CANCER RESEARCH

Gold nanoparticles cellular toxicity and recovery: Effect of size, concentration and exposure time

(2010) Tatsiana Mironava et al.   Nanotoxicology

An index for characterization of nanomaterials in biological systems

(2010) Xin-Rui Xia et al.   Nature Nanotechnology

A Predictive Toxicological Paradigm for the Safety Assessment of Nanomaterials

(2009) Huan Meng et al.   ACS Nano

Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rats

(2009) Suresh K. Balasubramanian et al.   BIOMATERIALS

Comparison of Quantum Dot Biodistribution with a Blood-Flow-Limited Physiologically Based Pharmacokinetic Model

(2009) Hyun A. Lee et al.   NANO LETTERS

Biodistribution of maltose and gum arabic hybrid gold nanoparticles after intravenous injection in juvenile swine

(2009) Genevieve M. Fent et al.   Nanomedicine-Nanotechnology Biology and Medicine

Organ weights and blood flows of sheep and pig for physiological pharmacokinetic modelling

(2008) Richard N. Upton   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS