Highly Potent Antisense Oligonucleotides Locked Nucleic Acid Gapmers Targeting the SARS-CoV-2 RNA Genome

Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection

(2023) Vignesh N. Hariharan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ex vivo and in vivo suppression of SARS-CoV-2 with combinatorial AAV/RNAi expression vectors

(2022) Jonas Becker et al.   MOLECULAR THERAPY

An intranasal ASO therapeutic targeting SARS-CoV-2

(2022) Chi Zhu et al.   Nature Communications

Understanding the Pharmacology of COVID-19 mRNA Vaccines: Playing Dice with the Spike?

(2022) Marco Cosentino et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms

(2021) Nicholas C. Huston et al.   MOLECULAR CELL

Genome-scale deconvolution of RNA structure ensembles

(2021) Edoardo Morandi et al.   NATURE METHODS

Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets

(2021) Rory D. de Vries et al.   SCIENCE

Silencing of SARS‐CoV‐2 with modified siRNA‐peptide dendrimer formulation

(2021) Musa Khaitov et al.   ALLERGY

A SARS-CoV-2 targeted siRNA-nanoparticle therapy for COVID-19

(2021) Adi Idris et al.   MOLECULAR THERAPY

REGEN-COV Antibody Combination and Outcomes in Outpatients with Covid-19

(2021) David M. Weinreich et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread

(2021) Shubhankar Ambike et al.   NUCLEIC ACIDS RESEARCH

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

SARS-CoV-2/COVID-19: a primer for cardiologists

(2020) A. A. F. de Vries   Netherlands Heart Journal

De novo design of picomolar SARS-CoV-2 miniprotein inhibitors

(2020) Longxing Cao et al.   SCIENCE

Structural and functional conservation of cis -acting RNA elements in coronavirus 5'-terminal genome regions

(2018) Ramakanth Madhugiri et al.   VIROLOGY

Small molecules targeting viral RNA

(2016) Thomas Hermann   Wiley Interdisciplinary Reviews-RNA

The structure and functions of coronavirus genomic 3′ and 5′ ends

(2015) Dong Yang et al.   VIRUS RESEARCH

RNA therapeutics: beyond RNA interference and antisense oligonucleotides

(2012) Ryszard Kole et al.   NATURE REVIEWS DRUG DISCOVERY