Evaluation of the non-linearity of NA808 in liver not reflected in plasma using a rat pharmacokinetic study and PBPK modelling

Construction of a culture protocol for functional bile canaliculi formation to apply human iPS cell-derived hepatocytes for cholestasis evaluation

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Evaluation of Drug Biliary Excretion Using Sandwich-Cultured Human Hepatocytes

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Comparison of uptake transporter functions in hepatocytes in different species to determine the optimal model for evaluating drug transporter activities in humans

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Stereoselective synthesis of the viridiofungin analogue NA808 from a chiral tetrahydrofuran-carboxylic acid

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OATP and MRP2-mediated hepatic uptake and biliary excretion of eprosartan in rat and human

(2014) Pengyuan Sun et al.   Pharmacological Reports

A Serine Palmitoyltransferase Inhibitor Blocks Hepatitis C Virus Replication in Human Hepatocytes

(2013) Asao Katsume et al.   GASTROENTEROLOGY

ATP-dependent transport of statins by human and rat MRP2/Mrp2

(2013) Lucy C.J. Ellis et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Self-Enhancement of Hepatitis C Virus Replication by Promotion of Specific Sphingolipid Biosynthesis

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Physiologically Based Pharmacokinetic Modeling to Predict Transporter-Mediated Clearance and Distribution of Pravastatin in Humans

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