IL-36 receptor deletion attenuates lung injury and decreases mortality in murine influenza pneumonia

IL-36γ is secreted in microparticles and exosomes by lung macrophages in response to bacteria and bacterial components

(2016) Melissa A. Kovach et al.   JOURNAL OF LEUKOCYTE BIOLOGY

IL-36γ Transforms the Tumor Microenvironment and Promotes Type 1 Lymphocyte-Mediated Antitumor Immune Responses

(2015) Xuefeng Wang et al.   CANCER CELL

Regulation and function of interleukin-36 cytokines in homeostasis and pathological conditions

(2015) Cem Gabay et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Interleukin-36γ is expressed by neutrophils and can activate microglia, but has no role in experimental autoimmune encephalomyelitis

(2015) Lusine Bozoyan et al.   Journal of Neuroinflammation

Respiratory Infections Cause the Release of Extracellular Vesicles: Implications in Exacerbation of Asthma/COPD

(2014) Suffwan Eltom et al.   PLoS One

P2X4 receptor regulates P2X7 receptor-dependent IL-1β and IL-18 release in mouse bone marrow-derived dendritic cells

(2013) Hayato Sakaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Monoclonal antibody against CXCL-10/IP-10 ameliorates influenza A (H1N1) virus induced acute lung injury

(2013) Wei Wang et al.   CELL RESEARCH

Cytokine and Chemokine Levels in Patients Infected With the Novel Avian Influenza A (H7N9) Virus in China

(2013) Y. Chi et al.   JOURNAL OF INFECTIOUS DISEASES

Pathogenesis of influenza-induced acute respiratory distress syndrome

(2013) Kirsty R Short et al.   LANCET INFECTIOUS DISEASES

Gateway to understanding microparticles: standardized isolation and identification of plasma membrane-derived vesicles

(2013) Sip Dinkla et al.   Nanomedicine

Macrophage-expressed IFN-β Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia

(2013) Katrin Högner et al.   PLoS Pathogens

CXCL10-CXCR3 Enhances the Development of Neutrophil-mediated Fulminant Lung Injury of Viral and Nonviral Origin

(2012) Akihiko Ichikawa et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells

(2012) S. Vigne et al.   BLOOD

Role of microparticles in sepsis

(2012) V.L. Reid et al.   BRITISH JOURNAL OF ANAESTHESIA

Psoriasiform dermatitis is driven by IL-36–mediated DC-keratinocyte crosstalk

(2012) Luigi Tortola et al.   JOURNAL OF CLINICAL INVESTIGATION

The Double-Stranded RNA Analogue Polyinosinic-Polycytidylic Acid Induces Keratinocyte Pyroptosis and Release of IL-36γ

(2012) Li-Hua Lian et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study

(2012) Fatimah S Dawood et al.   LANCET INFECTIOUS DISEASES

IL-36α Exerts Pro-Inflammatory Effects in the Lungs of Mice

(2012) Ravisankar A. Ramadas et al.   PLoS One

Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis

(2011) Teluguakula Narasaraju et al.   AMERICAN JOURNAL OF PATHOLOGY

An Official American Thoracic Society Workshop Report: Features and Measurements of Experimental Acute Lung Injury in Animals

(2011) Gustavo Matute-Bello et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IL-17 response mediates acute lung injury induced by the 2009 Pandemic Influenza A (H1N1) Virus

(2011) Chenggang Li et al.   CELL RESEARCH

IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression

(2011) A. Johnston et al.   JOURNAL OF IMMUNOLOGY

Inter-Regulation of Th17 Cytokines and the IL-36 Cytokines In Vitro and In Vivo: Implications in Psoriasis Pathogenesis

(2011) Yijun Carrier et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Contribution of neutrophil-derived myeloperoxidase in the early phase of fulminant acute respiratory distress syndrome induced by influenza virus infection

(2011) Ryuichi Sugamata et al.   MICROBIOLOGY AND IMMUNOLOGY

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(2011) Jochen Grommes et al.   MOLECULAR MEDICINE

Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis

(2011) Slaheddine Marrakchi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interleukin-1 Family Member 9 Stimulates Chemokine Production and Neutrophil Influx in Mouse Lungs

(2010) Ravisankar A. Ramadas et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Regulation and Function of the IL-1 Family Cytokine IL-1F9 in Human Bronchial Epithelial Cells

(2010) Regina T. Chustz et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Delayed Clearance of Viral Load and Marked Cytokine Activation in Severe Cases of Pandemic H1N1 2009 Influenza Virus Infection

(2010) Kelvin K. W. To et al.   CLINICAL INFECTIOUS DISEASES

Activation of pulmonary invariant NKT cells leads to exacerbation of acute lung injury caused by LPS through local production of IFN-  and TNF-  by Gr-1+ monocytes

(2010) T. Aoyagi et al.   INTERNATIONAL IMMUNOLOGY

Externalization of the Leaderless Cytokine IL-1F6 Occurs in Response to Lipopolysaccharide/ATP Activation of Transduced Bone Marrow Macrophages

(2009) U. Martin et al.   JOURNAL OF IMMUNOLOGY

Critical Role of IL-17RA in Immunopathology of Influenza Infection

(2009) C. R. Crowe et al.   JOURNAL OF IMMUNOLOGY

Critical Role of IL-1 Receptor-Associated Kinase-M in Regulating Chemokine-Dependent Deleterious Inflammation in Murine Influenza Pneumonia

(2009) M. Seki et al.   JOURNAL OF IMMUNOLOGY

Tc17, a Unique Subset of CD8 T Cells That Can Protect against Lethal Influenza Challenge

(2009) H. Hamada et al.   JOURNAL OF IMMUNOLOGY

Lung epithelial apoptosis in influenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligand

(2008) Susanne Herold et al.   JOURNAL OF EXPERIMENTAL MEDICINE