Asiatic Acid Attenuates Myocardial Ischemia/Reperfusion Injury via Akt/GSK-3β/HIF-1α Signaling in Rat H9c2 Cardiomyocytes

Hydroxytyrosol Protects against Myocardial Ischemia/Reperfusion Injury through a PI3K/Akt-Dependent Mechanism

(2016) Ying-hao Pei et al.   MEDIATORS OF INFLAMMATION

Neuroprotective effect of asiatic acid on rotenone-induced mitochondrial dysfunction and oxidative stress-mediated apoptosis in differentiated SH-SYS5Y cells

(2016) Jagatheesan Nataraj et al.   NUTRITIONAL NEUROSCIENCE

Glucose uptake through translocation and activation of GLUT4 in PI3K/Akt signaling pathway by asiatic acid in diabetic rats

(2015) V Ramachandran et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Antioxidative and Antiinflammatory Activities of Asiatic Acid, Glycyrrhizic Acid, and Oleanolic Acid in Human Bronchial Epithelial Cells

(2015) Shih-ming Tsao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Asiatic acid inhibits left ventricular remodeling and improves cardiac function in a rat model of myocardial infarction

(2015) LIANYING HUO et al.   Experimental and Therapeutic Medicine

Anti-apoptotic and anti-glycative effects of asiatic acid in the brain of d-galactose treated mice

(2015) Pei-chun Chao et al.   Food & Function

HIF-1 reduces ischaemia–reperfusion injury in the heart by targeting the mitochondrial permeability transition pore

(2014) Sang-Ging Ong et al.   CARDIOVASCULAR RESEARCH

Asiatic Acid Alleviates Hemodynamic and Metabolic Alterations via Restoring eNOS/iNOS Expression, Oxidative Stress, and Inflammation in Diet-Induced Metabolic Syndrome Rats

(2014) Poungrat Pakdeechote et al.   Nutrients

HIF-1α in heart: Protective mechanisms

(2013) Joe Wu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hydrogen sulfide prevents OGD/R-induced apoptosis via improving mitochondrial dysfunction and suppressing an ROS-mediated caspase-3 pathway in cortical neurons

(2013) Yougen Luo et al.   NEUROCHEMISTRY INTERNATIONAL

Asiatic acid, a pentacyclic triterpene in Centella asiatica, attenuates glutamate-induced cognitive deficits in mice and apoptosis in SH-SY5Y cells

(2012) Min-fang Xu et al.   ACTA PHARMACOLOGICA SINICA

Aldose reductase modulates cardiac glycogen synthase kinase-3β phosphorylation during ischemia-reperfusion

(2012) Mariane Abdillahi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Activation of HIF-1 by metallothionein contributes to cardiac protection in the diabetic heart

(2012) Wanli Xue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Redox Signaling in Cardiac Physiology and Pathology

(2012) Joseph R. Burgoyne et al.   CIRCULATION RESEARCH

Asiatic acid protects primary neurons against C2-ceramide-induced apoptosis

(2012) Xiangnan Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Hypoxia-inducible factor as a therapeutic target for cardioprotection

(2012) Sang-Ging Ong et al.   PHARMACOLOGY & THERAPEUTICS

Asiatic Acid Attenuates Infarct Volume, Mitochondrial Dysfunction, and Matrix Metalloproteinase-9 Induction After Focal Cerebral Ischemia

(2012) Ki Yong Lee et al.   STROKE

Nogo-A knockdown inhibits hypoxia/reoxygenation-induced activation of mitochondrial-dependent apoptosis in cardiomyocytes

(2011) J.P. Sarkey et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Oxidative stress caused by mitochondrial calcium overload

(2010) Tsung-I Peng et al.   Annals of the New York Academy of Sciences

HIF-1 inhibition decreases systemic vascular remodelling diseases by promoting apoptosis through a hexokinase 2-dependent mechanism

(2010) Caroline M. Lambert et al.   CARDIOVASCULAR RESEARCH

Asiatic acid preserves beta cell mass and mitigates hyperglycemia in streptozocin-induced diabetic rats

(2010) Jun Liu et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Expression of phosphorylated Akt in oral carcinogenesis and its induction by nicotine and alkaline stimulation

(2010) Ho-Tai Wu et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Role of Glycogen Synthase Kinase-3β in Cardioprotection

(2009) Magdalena Juhaszova et al.   CIRCULATION RESEARCH

Asiatic acid, a pentacyclic triterpene fromCentella asiatica, is neuroprotective in a mouse model of focal cerebral ischemia

(2009) Rajanikant G. Krishnamurthy et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Tissue kallikrein promotes neovascularization and improves cardiac function by the Akt-glycogen synthase kinase-3  pathway

(2008) Y.-Y. Yao et al.   CARDIOVASCULAR RESEARCH

Inhibition of GSK3β by Postconditioning Is Required to Prevent Opening of the Mitochondrial Permeability Transition Pore During Reperfusion

(2008) Ludovic Gomez et al.   CIRCULATION

Hypoxia-induced compensatory effect as related to Shh and HIF-1α in ischemia embryo rat heart

(2008) Jin-Ming Hwang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mechanisms Underlying Acute Protection From Cardiac Ischemia-Reperfusion Injury

(2008) Elizabeth Murphy et al.   PHYSIOLOGICAL REVIEWS