Unraveling the roles of aromatic cluster side-chain interactions on the structural stability and functional significance of psychrophilic Sphingomonas sp. glutaredoxin 3

Tyr76 is essential for the cold adaptation of a class II glutaredoxin 4 with a heat‐labile structure from the Arctic bacterium Sphingomonas sp.

(2023) Trang Hoang et al.   FEBS Open Bio

New insights on thioredoxins (Trxs) and glutaredoxins (Grxs) by in silico amino acid sequence, phylogenetic and comparative structural analyses in organisms of three domains of life

(2022) Soumila Mondal et al.   Heliyon

Hinge-shift mechanism as a protein design principle for the evolution of β-lactamases from substrate promiscuity to specificity

(2021) Tushar Modi et al.   Nature Communications

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Glutaredoxin: Discovery, redox defense and much more

(2021) Fernando T. Ogata et al.   Redox Biology

Essential roles of buried phenylalanine in the structural stability of thioredoxin from a psychrophilic Arctic bacterium Sphingomonas sp.

(2021) Thu-Thuy Nguyen et al.   PLoS One

The Role of Conformational Dynamics and Allostery in Modulating Protein Evolution

(2020) Paul Campitelli et al.   Annual Review of Biophysics

Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins

(2020) Linda Liedgens et al.   Nature Communications

Molecular basis for the distinct functions of redox-active and FeS-transfering glutaredoxins

(2020) Daniel Trnka et al.   Nature Communications

Protein folding stability and binding interactions through the lens of evolution: a dynamical perspective

(2020) Tushar Modi et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Hydrophobic surface residues can stabilize a protein through improved water‐protein interactions

(2019) Mohammad M. Islam et al.   FEBS Journal

Phylogenetic distribution and structural analyses of cyanobacterial glutaredoxins (Grxs)

(2019) Soumila Mondal et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Ancient thioredoxins evolved to modern-day stability–function requirement by altering native state ensemble

(2018) Tushar Modi et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Making sense of the past: hyperstability of ancestral thioredoxins explained by free energy simulations

(2017) Álvaro Cortés Cabrera et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Glutaredoxin catalysis requires two distinct glutathione interaction sites

(2017) Patricia Begas et al.   Nature Communications

The specificity of thioredoxins and glutaredoxins is determined by electrostatic and geometric complementarity

(2015) Carsten Berndt et al.   Chemical Science

Thioredoxins, Glutaredoxins, and Peroxiredoxins—Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling

(2013) Eva-Maria Hanschmann et al.   ANTIOXIDANTS & REDOX SIGNALING

The thioredoxin antioxidant system

(2013) Jun Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Utility of Synechocystis sp. PCC 6803 glutaredoxin A as a platform to study high-resolution mutagenesis of proteins

(2013) David B. Knaff et al.   Frontiers in Plant Science

Genome Sequence of Sphingomonas sp. Strain PAMC 26621, an Arctic-Lichen-Associated Bacterium Isolated from a Cetraria sp.

(2012) H. Lee et al.   JOURNAL OF BACTERIOLOGY

Polar and Alpine Microbial Collection (PAMC): a culture collection dedicated to polar and alpine microorganisms

(2012) Yung Mi Lee et al.   POLAR BIOLOGY

Single-molecule paleoenzymology probes the chemistry of resurrected enzymes

(2011) Raul Perez-Jimenez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Determinants of activity in glutaredoxins: anin vitroevolved Grx1-like variant ofEscherichia coliGrx3

(2010) Tobias H. Elgán et al.   BIOCHEMICAL JOURNAL

NMR structure of oxidized Escherichia coli glutaredoxin: Comparison with reduced E. coli glutaredoxin and functionally related proteins

(2010) Tai-He Xia et al.   PROTEIN SCIENCE

Evolution based on domain combinations: the case of glutaredoxins

(2009) Rui Alves et al.   BMC EVOLUTIONARY BIOLOGY

Evolution and diversity of glutaredoxins in photosynthetic organisms

(2009) Jérémy Couturier et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Glutaredoxins: roles in iron homeostasis

(2009) Nicolas Rouhier et al.   TRENDS IN BIOCHEMICAL SCIENCES

An Atlas of the Thioredoxin Fold Class Reveals the Complexity of Function-Enabling Adaptations

(2009) Holly J. Atkinson et al.   PLoS Computational Biology