Cryptolepine, a Plant Alkaloid, Inhibits the Growth of Non-Melanoma Skin Cancer Cells through Inhibition of Topoisomerase and Induction of DNA Damage

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Bioactive proanthocyanidins inhibit growth and induce apoptosis in human melanoma cells by decreasing the accumulation of β-catenin

(2015) MUDIT VAID et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells

(2015) Harish Chandra Pal et al.   Oncotarget

Honokiol inhibits the growth of head and neck squamous cell carcinoma by targeting epidermal growth factor receptor

(2015) Tripti Singh et al.   Oncotarget

Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the US Population, 2012

(2015) Howard W. Rogers et al.   JAMA Dermatology

Down-regulation of miRNA-106b inhibits growth of melanoma cells by promoting G1-phase cell cycle arrest and reactivation of p21/WAF1/Cip1 protein

(2015) Ram Prasad et al.   Oncotarget

Anti-neuroinflammatory properties of synthetic cryptolepine in human neuroblastoma cells: Possible involvement of NF-κB and p38 MAPK inhibition

(2013) Olumayokun A. Olajide et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of Neuroinflammation in LPS-Activated Microglia by Cryptolepine

(2013) Olumayokun A. Olajide et al.   Evidence-based Complementary and Alternative Medicine

Fisetin inhibits growth, induces G2/M arrest and apoptosis of human epidermoid carcinoma A431 cells: role of mitochondrial membrane potential disruption and consequent caspases activation

(2013) Harish C. Pal et al.   EXPERIMENTAL DERMATOLOGY

Proteomic Identification of a Direct Role for Cyclin D1 in DNA Damage Repair

(2012) S. Jirawatnotai et al.   CANCER RESEARCH

Acetylation is indispensable for p53 antiviral activity

(2011) Cesar Muñoz-Fontela et al.   CELL CYCLE

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA

(2011) Michael G. Kemp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Silymarin Protects Epidermal Keratinocytes from Ultraviolet Radiation-Induced Apoptosis and DNA Damage by Nucleotide Excision Repair Mechanism

(2011) Santosh K. Katiyar et al.   PLoS One

DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs

(2010) Yves Pommier et al.   CHEMISTRY & BIOLOGY

A Journey in the World of DNA Rings and Beyond

(2009) James C. Wang   Annual Review of Biochemistry

Cyclin E Is Stabilized in Response to Replication Fork Barriers Leading to Prolonged S Phase Arrest

(2009) Xiaoyan Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-inflammatory properties of cryptolepine

(2009) Olumayokun A. Olajide et al.   PHYTOTHERAPY RESEARCH

Acetylation Is Indispensable for p53 Activation

(2008) Yi Tang et al.   CELL

Characterization of the cytotoxic activity of the indoloquinoline alkaloid cryptolepine in human tumour cell lines and primary cultures of tumour cells from patients

(2008) Daniel Laryea et al.   INVESTIGATIONAL NEW DRUGS