Article
Multidisciplinary Sciences
Rabaa Algotiml, Ali Gab-Alla, Roshdi Seoudi, Hussein H. Abulreesh, Mahmoud Zaki El-Readi, Khaled Elbanna
Summary: The study successfully synthesized silver nanoparticles using different marine algae extracts, which showed potential applications in antimicrobial, anticancer, and antifungal activities. Particularly, silver nanoparticles capped with Ulva rigida extract exhibited high anticancer activity.
SCIENTIFIC REPORTS
(2022)
Article
Plant Sciences
Kelthoum Tarfaoui, Najiba Brhadda, Rabea Ziri, Asmaa Oubihi, Hamada Imtara, Sara Haida, Omkulthom M. Al Kamaly, Asmaa Saleh, Mohammad Khalid Parvez, Saad Fettach, Mohammed Ouhssine
Summary: This study analyzed the essential oil composition of ginger and cardamom, identified numerous compounds, and tested their antibacterial activity against bacteria and yeast. Additionally, the antioxidant activity of the oils and extracts was evaluated.
Article
Materials Science, Multidisciplinary
M. F. H. Abd El-Kader, M. T. Elabbasy, M. K. Ahmed, A. A. Menazea
Summary: AgNPs@PVA/PVP blends fabricated using laser ablation technique exhibit controlled particle size and distribution, with increased particle size as ablation time is prolonged. The addition of silver nanoparticles leads to reduced contact angle and improved cell viability, along with strong antibacterial activity against Escherichia coli and Staphylococcus aureus.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Article
Biochemistry & Molecular Biology
Aftab Alam, Najeeb Ur Rehman, Mohd Nazam Ansari, Amber Hanif Palla
Summary: The chemical composition, antimicrobial properties, and gastrointestinal activity of the essential oils of Elettaria cardamomum harvested in India (EC-I) and Guatemala (EC-G) were compared. EC-I showed higher concentration of monoterpenes and exhibited stronger inhibitory effects against bacteria and more effective treatment in a diarrhea model compared to EC-G.
Article
Nanoscience & Nanotechnology
N. Reddy, Huizhen Li, Tianyu Hou, M. S. Bethu, Zhiqing Ren, Zhijun Zhang
Summary: This study successfully synthesized PF@AgNPs using Perilla frutescens leaf extract, which possess antibacterial, antioxidant, and anticancer activities. PF@AgNPs showed good physical properties and significant inhibition activities against various cancer cell lines.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Plant Sciences
Nenad L. Vukovic, Milena D. Vukic, Ana D. Obradovic, Milos M. Matic, Lucia Galovicova, Miroslava Kacaniova
Summary: This study evaluated the effects of Spanish marjoram and cardamom essential oils on human breast cancer cells, antimicrobial activity, and antibiofilm effect. The results showed inhibitory effects of both essential oils on cell viability, antioxidative potential, and nitric oxide levels of breast cancer cells after long-term treatment. The essential oils also exhibited antimigratory effects, suggesting their potential in preventing tumor progression and growth. Antimicrobial tests revealed that marjoram essential oil was most effective against Candida glabrata and Listeria monocytogenes, while cardamom essential oil showed the best antibiofilm activity against Pseudomas fluorescens. The study highlights the potential use of these essential oils in various industries.
Article
Nanoscience & Nanotechnology
Wei Ha, Jun-Li Yang, Yan-Ping Shi
Summary: In recent years, there has been increasing attention on antibacterial nanosystems for cancer treatment involving bacterial infection. Silver nanoparticles (AgNPs) are widely used for their long-lasting and broad-spectrum antibacterial activity, but their inert surfaces make it difficult to load and deliver anticancer agents directly. This study developed biocompatible silver nanoparticles (TA-AgNPs) using tannic acid as a reducing and stabilizing agent. The TA-AgNPs exhibited low cytotoxicity and significant antibacterial activity. They could also effectively load and deliver the anticancer drug epirubicin hydrochloride (EPI), and showed pH- and GSH-sensitive drug release performance. The TA-AgNPs/EPI nanodrug demonstrated equal cytotoxicity to free EPI against cancer cells and prevented the influence of bacteria on EPI cytotoxicity.
ACS APPLIED NANO MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Yingshan Jin, Yuting Lu, Anbazhagan Sathiyaseelan, Xin Zhang, Kumar Vishven Naveen, Myeong-Hyeon Wang
Summary: Peony seed cake extract (PSCE) was used to synthesize silver nanoparticles (Ag NPs) with antibacterial, antioxidant, and cytotoxicity properties. The PSCE-Ag NPs showed a spherical shape, average size of 105.6 ± 3.49 nm, and a zeta potential of -41.8 ± 12.6 mV. They effectively inhibited the growth and biofilm formation of various bacteria and exhibited strong free radical scavenging ability. Furthermore, the PSCE-Ag NPs were non-toxic to erythrocytes, egg-chorioallantoic membrane, and human embryonic kidney cells (HEK293), while significantly suppressing breast cancer cell (BT474) growth.
Article
Materials Science, Multidisciplinary
Samuel Ruiz, Fei Wang, Lei Liu, Yongfeng Lu, Bin Duan, Lee E. Korshoj, Tammy Kielian, Bai Cui
Summary: Ag nanoparticles were synthesized using a nanosecond pulsed laser ablation process, and their antibacterial properties were studied, showing potential for biomedical applications.
JOURNAL OF LASER APPLICATIONS
(2022)
Article
Multidisciplinary Sciences
Mohamed Taha Yassin, Ashraf Abdel-Fattah Mostafa, Abdulaziz Abdulrahman Al-Askar, Abdulrahman S. Alkhelaif
Summary: Antimicrobial resistance is a significant issue in food poisoning strains, but Elettaria cardamomum extracts show strong antibacterial activity and can potentially be used as food preservatives to replace chemical preservatives and reduce the side effects of chemotherapy drugs.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Optics
A. S. Nikolov, N. E. Stankova, D. B. Karashanova, N. N. Nedyalkov, E. L. Pavlov, K. Tz Koev, Hr Najdenski, V Kussovski, L. A. Avramov, C. Ristoscu, M. Badiceanu, I. N. Mihailescu
Summary: This paper discusses the production of Ag nanoparticles in water solution through a two-phase pulsed laser method for therapeutic ophthalmological applications. By adjusting laser parameters, nanoparticles with sizes less than 10 nm and narrow size distribution were successfully obtained. The synthesized AgNPs colloidal aqueous solutions showed antimicrobial properties, especially against Pseudomonas aeruginosa and Escherichia coli, suggesting a potential non-invasive method for ocular infections prevention and treatment.
OPTICS AND LASER TECHNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Mayra Z. Trevino-Garza, Ana Karen Saldivar-Vazquez, Sonia Martha Lopez-Villarreal, Maria del Refugio Lara-Banda, Joel Horacio Elizondo-Luevano, Abelardo Chavez-Montes, Juan Gabriel Baez-Gonzalez, Osvelia Esmeralda Rodriguez-Luis
Summary: This research evaluated the performance of films based on developed linseed mucilage loaded with E. cardamom, C. officinalis, and both compounds. The inclusion of the active compounds altered the color and had no effect on film thickness. The films released the active compounds in artificial saliva within a solubilization time of 9 to 12 minutes. Additionally, the incorporation of these compounds increased the total phenolic content and antioxidant activity, while decreasing hardness, deformation, and fracturability of the films.
Article
Chemistry, Physical
Susan Hasan, Khawla S. S. Khashan, Aseel A. A. Hadi
Summary: In this study, Pd@Ag(core/shell) nanoparticles were synthesized using Q-switched Nd:YAG laser at a wavelength of 1064 nm in distilled water. The synthesized nanoparticles were characterized by various techniques, including UV-visible spectrophotometry, FT-IR, XRD, TEM, and EDS. The results showed that the Pd@Ag core-shell nanoparticles exhibited excellent antibacterial activity, especially against Gram-positive pathogens. The use of PLAL-prepared Pd@Ag core-shell nanoparticles as antimicrobial agents shows promising potential.
Article
Materials Science, Multidisciplinary
Kiseok Han, Anbazhagan Sathiyaseelan, Kandasamy Saravanakumar, Myeong-Hyeon Wang
Summary: In this study, quercetin was used to synthesize silver nanoparticles for enhanced antioxidant and antibacterial activity. The synthesized nanoparticles exhibited promising results in inhibiting bacterial growth and showed no toxicity towards cells.
Article
Optics
Shamsuddeen A. Haladu, Khaled A. Elsayed, Ibrahim Olanrewaju Alade, Muidh Alheshibri, Abbad Al Baroot, Shaikh A. Ali, Essam Kotb, Abdullah A. Manda, Anwar Ul-Hamid, Hatim D. M. Dafalla, Q. A. Drmosh
Summary: The therapeutic utilization of biodegradable polymers for controlled drug delivery is a promising approach. In this study, a green synthesis technique called Pulsed Laser Ablation of solids in liquid (PLAL) was used to fabricate nanoparticles for enhanced safety. Polyaspartate (PASP), a biodegradable polymer, was prepared by polycondensation of L-aspartic acid, and the AgNPs were synthesized by ablation of silver plate using a Q-switched Nd:YAG laser. The size and dispersity of the AgNPs were investigated by varying PASP concentrations. Antibacterial efficiency of the AgNPs was tested and the nanoparticles showed promising inhibition effect against Escherichia coli. The findings suggest that biofriendly PASP can be used as a capping agent for AgNPs and has potential as growth inhibitors against pathogenic bacterial strains.
OPTICS AND LASER TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Afraa Ali Kadhim, Nahida R. Abbas, Hussam H. Kadhum, Salim Albukhaty, Majid S. Jabir, Amel Muhson Naji, Sawsan S. Hamzah, Mustafa K. A. Mohammed, Hassan Al-Karagoly
Summary: This study investigated the effects of novel zinc oxide nanoparticles synthesized using Papaver somniferum leaf on oxidative stress, necrosis, and apoptosis in THP-1 cells. The nanoparticles showed an irregular spherical morphology with a size ranging from 20 to 30 nm. They inhibited cell proliferation in a concentration-dependent manner and induced necrosis and apoptosis in the cancer cell line. The nanoparticles also increased the formation of intracellular ROS, which is important for deactivating leukemic cell development.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Engineering, Environmental
Mastafa H. Al-Musawi, Mohsen Rashidi, Vahid Mohammadzadeh, Salim Albukhaty, Elham Mahmoudi, Marjan Ghorbani
Summary: This study introduces an easy method to produce high strength composite chitosan hydrogel by using Gallic acid as a cross-linking agent. The cross-linked hydrogel shows dense microstructure, good mechanical properties, high porosity, thermal stability, high swelling ratio, high antioxidant activity, and good biocompatibility. Adding quercetin loaded-Zein microsphere in the optimal hydrogel further enhances its characteristics, making it a promising material for tissue engineering.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Article
Biochemistry & Molecular Biology
Amal A. Alyamani, Mastafa H. Al-Musawi, Salim Albukhaty, Ghassan M. Sulaiman, Kadhim M. Ibrahim, Elsadig M. Ahmed, Majid S. Jabir, Hassan Al-Karagoly, Abed Alsalam Aljahmany, Mustafa K. A. Mohammed
Summary: The aim of this study was to create an antibacterial agent for wound dressing by using nanofibers loaded with Cordia myxa fruit extract (CMFE) in a polycaprolactone/chitosan (PCL/CH) matrix. Various characteristics including morphology, physicochemical properties, surface wettability, antibacterial activity, cell viability, and drug release were examined. The addition of CMFE in PCL/CH increased swelling capability and weight loss. The nanofiber mat showed uniform topology and exhibited excellent antimicrobial activity against various bacteria. The inclusion of CMFE also resulted in lower water contact angle, high porosity, and swelling. The drug release from the nanofiber mat followed non-Fickian diffusion. The nanofiber membrane demonstrated cytocompatibility and can be utilized as an effective wound dressing material.
Article
Physics, Multidisciplinary
Mayyadah H. Mohsin, Khawla S. Khashan, Ghassan M. Sulaiman
Summary: In this paper, hexagonal BN, Gd2O3 nanoparticles, and BN@Gd2O3 hybrid nanocomposites were synthesized by novel laser ablation in liquid. Various analytical techniques were used to investigate their structural and optical properties. The results showed the formation of h-BN NPs, sheet-like and spherical nanoparticles, hexagonal-type nanoflake of Gd2O3, and needle-like shapes. The optical energy gap of h-BN, Gd2O3, and h-BN@Gd2O3 was found to be in the range of (4.5-5.5) eV.
Article
Chemistry, Medicinal
Atiaf Rhyaf, Hala Naji, Hassan Al-Karagoly, Salim Albukhaty, Ghassan M. Sulaiman, Abdulaziz Arif A. Alshammari, Hamdoon A. Mohammed, Majid Jabir, Riaz A. Khan
Summary: Combining bovine serum albumin with microemulsions as a biopolymer ingredient is an innovative method for addressing surface functionalization and stability issues in targeted payload deliveries. The current study aimed to develop an efficient microemulsion system encapsulating sesame oil as a model payload for efficient delivery. Characterization and analysis of the developed carrier were performed using UV-VIS, FT-IR, and FE-SEM. Physicochemical properties of the microemulsion were assessed and analyzed using dynamic light scattering, zeta potential, electron microscopy, and rheological behavior. In vitro and in vivo assays were conducted to evaluate cell viability, biocompatibility, and toxicity.
Article
Materials Science, Biomaterials
Sumaiya Naeema Hawar, Zainab K. Taha, Atyaf Saied Hamied, Hanady S. Al-Shmgani, Ghassan M. Sulaiman, Sobhy E. Elsilk
Summary: This study evaluated the antifungal activities of secondary metabolites from Paecilomyces sp. against the pathogenic fungus Rhizoctonia solani. The results showed that the secondary metabolites of Paecilomyces possessed inhibitory effects on the radial growth of Rhizoctonia solani. The ethyl acetate extract of Paecilomyces sp. contained several important chemical components.
INTERNATIONAL JOURNAL OF BIOMATERIALS
(2023)
Article
Chemistry, Physical
Ivan Pires de Oliveira, Caroline Honaiser Lescano, William James Nogueira Lima, Ulisses Alves Pereira, Charles Martins Aguilar, V. Velusamy, P. Sasikumar, M. Vimalan, K. Ganesh Kumar, K. Senthilkannan
Summary: Diesohol, consisting of ethanol and diesel, is a potential alternative for diesel. The physical parameters such as density, ultrasound velocity, viscosity, and surface tension were measured to obtain the inference results. The molecular association between the mixture and diesel is similar, indicating significant hydrogen bonding interaction.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Medicinal
Omar Messaoudi, Ibrahim Benamar, Ahmed Azizi, Salim Albukhaty, Yasmina Khane, Ghassan M. Sulaiman, Mounir M. Salem-Bekhit, Kaouthar Hamdi, Sirine Ghoummid, Abdelhalim Zoukel, Ilhem Messahli, Yacine Kerchich, Farouk Benaceur, Mohamed M. Salem, Mourad Bendahou
Summary: In this study, hybrid nanoparticles synthesized through the green method showed significant antimicrobial activity and the ability to remove biofilm.
Article
Biotechnology & Applied Microbiology
Ameer A. Imarah, Majid S. Jabir, Ali H. Abood, Ghassan M. Sulaiman, Salim Albukhaty, Hamdoon A. Mohammed, Riaz A. Khan, Hayder M. Al-Kuraishy, Ali Al-Gareeb, Waleed K. Al-Azzawi, Mazin A. Najm, Sabrean F. Jawad
Summary: In this study, the cytotoxic effects of graphene oxide nanoparticles (GONPs) were evaluated using MTT assays, observation of apoptotic markers, and oxidative stress. Significant cytotoxic and apoptotic effects were observed. Analyses of CYP2E1 and malondialdehyde concentrations confirmed the toxicity of GONPs, while the levels of glutathione showed a reduction compared to the control. The alterations in cytochrome CYP2E1, glutathione, malondialdehyde, and caspase-3 suggest an interlinked relationship.
Article
Agriculture, Multidisciplinary
Mahasen Khudier, Hassan A. Hammadi, Hiba T. Atyia, Hassan Al-Karagoly, Salim Albukhaty, Ghassan M. Sulaiman, Yaser H. Dewir, Hameed B. Mahood
Summary: Green synthesized selenium nanoparticles using Vaccinium arctostaphylos L. fruit extract were evaluated for their antibacterial activity against Staphylococcus aureus, Escherichia coli, and Corynebacterium diphtheriae. The synthesized nanoparticles exhibited spherical shape and uniform size. The results showed that the nanoparticles had a significant inhibitory effect on bacterial growth, making them a desirable option for preventing bacterial infections.
COGENT FOOD & AGRICULTURE
(2023)
Article
Chemistry, Physical
Yasameen K. Al-Majedy, Hiba H. Ibraheem, Ali Abdullah Issa, Majid S. Jabir, Buthenia A. Hasoon, Hanady S. Al-Shmgani, Ghassan M. Sulaiman
Summary: Coumarins and their derivatives, such as coumarinyl chalcone, have significant pharmacological effects, including antioxidant, antibacterial, and anticancer activity. This study synthesized different compounds and evaluated their biomedical properties, finding that compound (C) exhibited the highest antioxidant and antibacterial activity and inhibited the growth of breast cancer cells.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
