Article
Multidisciplinary Sciences
Brato Chakrabarti, Sebastian Furthauer, Michael J. Shelley
Summary: The study reveals the formation mechanism of metachronal waves generated by motile cilia under the action of internal molecular motors. The research also highlights the important role of boundaries and inhomogeneities in nonuniform ciliary tissues in promoting metachronal waves.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Automation & Control Systems
Hao Jiang, Hongri Gu, Bradley J. Nelson, Teng Zhang
Summary: A computational model is developed to simulate the deformation of single cilium, metachronal wave motion of multiple cilia, and locomotion of magnetic cilia soft robots. The simulations provide insights into the spatial and temporal variation of friction forces and trajectories of cilia tips, contributing to the understanding of metachronal wave-modulated locomotion. The developed model also has the potential to guide the design and optimization of magnetic soft robots.
ADVANCED INTELLIGENT SYSTEMS
(2023)
Article
Mathematics, Interdisciplinary Applications
Hina Sadaf, Zeeshan Asghar, Naheeda Iftikhar
Summary: This report presents a comprehensive analysis of the laminar cross fluid model with cilia-driven flow in a horizontal channel, discussing the development, results, and comparisons with peristaltic channels. The study utilizes non-Newtonian rheologies and transforms the equations of momentum and energy into ordinary differential equations. Numerical solutions are obtained using MATLAB's bvp4c technique, and graphical representations of stream function, velocity, pressure rise, and pressure gradient are provided. The proposed model focuses on the transportation of fundamental substances through ductus efferentes, considering the potential chemical reactions. The findings offer valuable insights for understanding the cilia's role in chemical impacts within the human body.
COMPUTATIONAL PARTICLE MECHANICS
(2023)
Article
Mechanics
Zeeshan Asghar, Muhammad Waris Saeed Khan, Amjad Ali Pasha, Mustafa Mutiur Rahman, L. Sankaralingam, Mohammad Irfan Alam
Summary: This study combines magnetohydrodynamics, Hall effects, and porous medium with cilia-driven flow. The findings suggest that combining high magnetic field and porous media with Carreau-Yasuda fluid improves the performance of pumping equipment compared to viscous liquid, and metachronal ciliary motion improves fluid movement in biological organs. This study is predicted to make a significant contribution to the upgrading and advancement of various types of drug-delivery technologies in biomedical engineering.
Article
Physics, Fluids & Plasmas
Timothy A. Westwood, Eric E. Keaveny
Summary: The study focuses on simulating hundreds of interacting active filaments on spherical surfaces, revealing that defects alter filament beating and cause sphere movement once released. This motion feedback to the filaments, resulting in a whirling state with metachronal behavior along the equator.
PHYSICAL REVIEW FLUIDS
(2021)
Article
Engineering, Chemical
A. A. Farooq, M. Kahshan, S. Saleem, Mohammad Rahimi-Gorji, Fahad S. Al-Mubaddel
Summary: The study investigates entropy production rate induced by ciliary pumping systems in bio-magnetic viscous materials, considering the effects of Hall currents, Hartmann number, and cilia length parameters on flow characteristics. It is found that the inclusion of Hall current can overcome the damping effects of magnetic field and control the disorderliness of thermodynamic systems, while longer cilia lengths stimulate momentum transfer and promote pumping rates in the axial flow direction.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2021)
Article
Multidisciplinary Sciences
Zhiwei Cui, Ye Wang, Shuaizhong Zhang, Tongsheng Wang, Jaap M. J. den Toonder
Summary: Researchers have developed a new method to generate periodic motion by integrating a paramagnetic substructure in the substrate underneath artificial cilia. By changing the relative positions of the substructure and artificial cilia, different types of periodic motion can be created. This research breaks the size limitation barrier in metachronal artificial cilia and showcases the potential of nature-inspired engineering.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Mathematics, Applied
Mubbashar Nazeer, Farooq Hussain, Sadia Iftikhar, Muhammad Ijaz Khan, K. Ramesh, Nasir Shehzad, Afifa Baig, Seifedine Kadry, Yu-Ming Chu
Summary: Peristaltic transport of couple stress fluid with heat transfer is studied in a channel with flexible walls furnished with hair-like structures. The simultaneous propagation of metachronal waves and peristaltic waves is found to be responsible for the locomotion of biological fluids. The study also highlights the resistive behavior of magnetic fields, viscous dissipation, and entropy generation in the two-dimensional rheological flow. Finally, a closed-form solution for the nonlinear coupled differential equation is achieved, showing the potential for efficiently removing mucus from the lungs and bloodstream through the manufacture of a ciliate bronchial tube.
NUMERICAL METHODS FOR PARTIAL DIFFERENTIAL EQUATIONS
(2021)
Article
Nanoscience & Nanotechnology
Shuaizhong Zhang, Zhiwei Cui, Ye Wang, Jaap den Toonder
Summary: A simple method to create metachronal microscopic magnetic artificial cilia (mu MAC) is demonstrated, allowing for strong microfluidic pumping and soft robot locomotion. These metachronal mu MAC show twice the pumping efficiency and three times the locomotion speed of synchronously moving mu MAC. The design also results in soft robots with unprecedented slope climbing ability and strong cargo-carrying capacity in dry and wet conditions.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Automation & Control Systems
Sunwoo Sohn, Hyoryong Lee, Hyeonwoo Kee, Sukho Park
Summary: This article introduces a self-assembly method to create a reprogrammable magnetically actuated cilia array that mimics the movement of motile cilia. By applying different magnetic fields, fluid mixing and pumping can be achieved.
ADVANCED INTELLIGENT SYSTEMS
(2023)
Article
Thermodynamics
Abdou Al-Zubaidi, Mubbashar Nazeer, Khadija Khalid, Sidra Yaseen, Salman Saleem, Farooq Hussain
Summary: This paper investigates heat and mass transfer analyses for Newtonian, Pseudo-plastic, and Dilatant fluids through a horizontal inclined channel with the motion of cilia. The study uses a perturbation method to analyze the behavior of velocity, temperature, and concentration profiles for all three types of fluids.
ADVANCES IN MECHANICAL ENGINEERING
(2021)
Article
Thermodynamics
S. Shaheen, H. Huang, M. B. Arain, A. Al-Zubaidi, Elsayed M. Tag-eldin
Summary: This study investigates the flow characteristics of cilia-induced fluid flow in a horizontal asymmetric channel with different viscosity, density, and thermal conductivity. The findings provide valuable insights for understanding and applying this phenomenon in the field of physiology.
CASE STUDIES IN THERMAL ENGINEERING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yusi Miao, Joseph C. Jing, Lidek Chou, Zhikai Zhu, Brian J. F. Wong, Zhongping Chen
Summary: The study presents a label-free high-speed visualization technique for ciliary metachronal wave propagations in freshly-excised tracheal explants. The technique can reliably and efficiently capture the spatial distribution and function of the waves. The phase-resolved dynamic wavefront imaging (PRDWI) method offers a more distinct visualization of the direction and coordination of collective cilia movement.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Multidisciplinary Sciences
Muhammad Sohail, Essam R. El-Zahar, Abd Allah A. Mousa, Umar Nazir, Saad Althobaiti, Ali Althobaiti, Nehad Ali Shah, Jae Dong Chung
Summary: This research discusses the enhancement of thermal performance by mixing nanoparticles in base fluid and conducts a study on a two-dimensional porous stretching sheet using a pseudo-plastic fluid model. The solution is approximated using the finite element method and the contribution of emerging parameters is displayed.
SCIENTIFIC REPORTS
(2022)
Article
Mathematics, Applied
Pramod Kumar Yadav, Amit Kumar Verma
Summary: The flow behavior of two immiscible fluids in an inclined channel made of two rigid plates is analyzed in this study, with the flow governed by Brinkman's equation. By solving the mathematical model, the effects of different parameters on linear velocity, microrotational velocity, flow rate, and stresses are evaluated and presented graphically. The results are validated against previous established results.
MATHEMATICAL METHODS IN THE APPLIED SCIENCES
(2022)