Article
Food Science & Technology
Lubomir Lapcik, David Repka, Barbora Lapcikova, Daniela Sumczynski, Shweta Gautam, Peng Li, Tomas Valenta
Summary: Corn silk extracts contain a variety of functional biological substances, such as flavonoids, polysaccharides, steroids, and polyphenols, which contribute to their antioxidant activity. The maturity stage of corn silk and the extraction method affect the radical scavenging capacity. Different maturity stages of corn silk samples exhibit varied antioxidant activity.
Article
Chemistry, Analytical
Yan Fang, Yangzom Dawa, Qilan Wang, Yue Lv, Wei Yu, Gang Li, Jun Dang
Summary: In this study, a technique was devised to separate 1,1-diphenyl-2-picrylhydrazyl inhibitors from Saxifraga atrata, an important traditional Tibetan medicine. The targeted separation process involved using medium-pressure liquid chromatography and reverse-phase liquid chromatography, resulting in the isolation of two 1,1-diphenyl-2-picrylhydrazyl inhibitors with high purity and inhibitory activity.
JOURNAL OF SEPARATION SCIENCE
(2022)
Article
Genetics & Heredity
Mohan Lal, Sunita Munda, Twahira Begum, Tanmita Gupta, Manabi Paw, Sanjoy Kumar Chanda, Himangshu Lekhak
Summary: Through the study of 135 genotypes of C. caesia, five high-yielding genotypes were identified, and one genotype was found to have the highest yield and stability in various environments. This research will contribute to the conservation and genetic resource management of C. caesia.
Article
Horticulture
Brigitte Liliana Moreno-Medina, Fanor Casierra-Posada, Oscar Julio Medina-Vargas
Summary: The aim of this study is to determine the phenolic profile and antioxidant capacity in blackberry fruits grown in Boyaca, Colombia. The study found that blackberries contain rich phenolic compounds and anthocyanins, which have antioxidant and various bioactive properties. Additionally, certain compounds were identified to significantly contribute to the color, antioxidant capacity, and other bioactive attributes of blackberries.
Article
Chemistry, Applied
Mohammad Al-Amin, Nagla Mustafa Eltayeb, Melati Khairuddean, Salizawati Muhamad Salhimi
Summary: The study isolated new compounds from Curcuma caesia and identified bioactive compounds, with curcuzederone showing significant inhibition of cancer cell migration, indicating its potential as a promising drug for cancer treatment.
NATURAL PRODUCT RESEARCH
(2021)
Article
Biotechnology & Applied Microbiology
Nurul Najiha Ain Ibrahim, Nurkhalida Kamal, Ahmed Mediani, Azliana Abu Bakar Sajak, Soo Yee Lee, Khozirah Shaari, Hafeedza Abdul Rahman
Summary: This study aims to determine the phenolic content, antioxidant, and alpha-glucosidase inhibitory activity of Curcuma caesia rhizome and leaves. The freeze-dried rhizome extracted with 100:0 ethanol and water showed the highest phenolic content, antioxidant activity, and alpha-glucosidase inhibitory activity. These findings suggest that the rhizomes of C. caesia are a valuable natural source of active ingredients for pharmaceutical and food industries.
FOOD TECHNOLOGY AND BIOTECHNOLOGY
(2023)
Article
Biochemical Research Methods
Lei Dai, Wei Huang, Lin-Lin Chen, Xiao Fang, Lin Wang, Xiao-Ping Ding, Jun-Feng Liu
Summary: A novel UPLC-PDC-DAD analysis technique was developed and successfully applied to screen active ingredients in Huanglian Jiedu decoction. The study identified the main active ingredients in Huanglian Jiedu decoction and found that there are multiple components with effective properties against diseases.
Article
Plant Sciences
Avinash Gangal, Manisha Duseja, Neeraj K. Sethiya
Summary: The study analyzed the phytochemical composition of the essential oil extracted from black turmeric rhizomes, and found that it contains various important compounds with potent antioxidant and alpha-amylase inhibitory activities.
JOURNAL OF ESSENTIAL OIL BEARING PLANTS
(2023)
Article
Environmental Sciences
Malgorzata Tatarczak-Michalewska, Jolanta Flieger
Summary: Antioxidant activity can be analyzed by various methods, but the widely used colorimetric method has limitations due to interference from photosynthetic pigments. DPPH-HPLC eliminates these limitations and enables simultaneous analysis of antioxidants and evaluation of their activity.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Infectious Diseases
Trusha Nana, Olga Perovic, Vindana Chibabhai
Summary: This laboratory-based study compared the carbapenem MICs yielded by Sensititre, Vitek 2, MicroScan WalkAway plus, and Etest for OXA-48-like Klebsiella pneumoniae isolates. The results showed substantial variability in carbapenem MICs, emphasizing the need for performance characteristics verification of MIC methods to ensure accurate reporting.
CLINICAL MICROBIOLOGY AND INFECTION
(2022)
Article
Chemistry, Multidisciplinary
Surya Iryana Ihsanpuro, Setiyo Gunawan, Roshita Ibrahim, Hakun Wirawasista Aparamarta
Summary: This study used microwave-assisted extraction (MAE) to extract the pericarp and seeds of mangosteen and compared the antioxidant activity of the two extracts. The results showed that the pericarp extract exhibited stronger antioxidant activity than the seed extract and slightly better than ascorbic acid.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Article
Oncology
Maryam Bayanati, Bahram Daraei, Afshin Zarghi
Summary: Cancer is the second leading cause of death worldwide, and selective cyclooxygenase-2 (COX-2) inhibitors have been found to have chemopreventive effects against different types of cancer. This study aimed to introduce a new COX-2 inhibitor structure with fewer side effects, and the results showed promising COX-2 inhibitory and anti-platelet activities for the synthesized compounds.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
(2023)
Article
Chemistry, Physical
L. Athishu Anthony, P. Nethaji, G. Sundararajan, D. Rajaraman
Summary: A novel compound BMNDPI was synthesized and characterized, and its properties were investigated using various analysis methods. The results of molecular docking suggest that BMNDPI may be a potential agent against COVID-19.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Applied
Manaswini Dash, Subhashree Singh, Bhaskar Chandra Sahoo, Suprava Sahoo, Rajesh Kumar Sahoo, Sanghamitra Nayak, Basudeba Kar
Summary: The study analyzed the volatile components in Piper longum leaf and fruit, showing that the fruit volatiles had higher antioxidant and free radical scavenging activities, exhibiting strong activity against multidrug resistant bacteria, particularly Acinetobacter baumannii. Therefore, dried fruits may be used for drug development.
NATURAL PRODUCT RESEARCH
(2022)
Review
Plant Sciences
Bhaskar Chandra Sahoo, Suprava Sahoo, Sanghamitra Nayak, Basudeba Kar
Summary: Zingerone is a nonvolatile and nontoxic compound found in ginger, with multiple pharmacological activities such as antimicrobial, antioxidant, and anti-inflammatory effects. This review summarizes the diverse pharmacological activities of zingerone against important diseases like cancer, inflammation, and infection, and discusses its molecular regulation.
PLANT SCIENCE TODAY
(2022)
Article
Biochemistry & Molecular Biology
Subhashree Singh, Suprava Sahoo, Bhaskar Chandra Sahoo, Manaswini Dash, Sanghamitra Nayak, Basudeba Kar
Summary: The essential oil of Kaempferia galanga L., commonly known as sand ginger, has been in high demand in the national and international market. This study evaluated the essential oil yield and constituents of 36 accessions from three provinces in Eastern India. It identified quality chemovars that can be used for commercial cultivation and further improvement of the taxa.
Article
Plant Sciences
Chandra Sekhar Tripathy, Bhaskar Chandra Sahoo, Manaswini Dash, Debasis Sahoo, Suprava Sahoo, Basudeba Kar
Summary: In this study, the physiochemical parameters of C. zedoaria cytochrome proteins were estimated using Expasy ProtParam web tool, and the secondary and tertiary structures were modeled and validated using SOPMA, MODELLER, QMEAN, and ProSA tools. These findings provide a basis for further research on the crystal structure, physiochemical properties, and protein-protein interactions of cytochrome proteins in this plant.
PLANT SCIENCE TODAY
(2022)
Article
Chemistry, Analytical
Bhaskar Chandra Sahoo, Subhashree Singh, Suprava Sahoo, Basudeba Kar
Summary: In this study, betelvine leaf essential oils from two landraces were analyzed using GC x GC TOFMS for the first time. A total of 181 constituents were identified, with 86 of them reported for the first time in the leaf essential oil. The major constituents identified were eugenol, chavibetol acetate, 4-ally-1,2-diacetoxybenzene, eugenol acetate, and chavibetol. This study provides a detailed characterization of betelvine oil and can contribute to novel drug discovery.
ANALYTICAL LETTERS
(2023)
Article
Genetics & Heredity
Suprava Sahoo, Bhaskar Chandra Sahoo, Subhashree Singh, Basudeba Kar, Sanghamitra Nayak
Summary: In this study, four Alpinia species and three Kaempferia species were analyzed using three PCR based molecular markers. The results showed that each marker produced unique banding patterns, and specific primers such as D20, D18, and D8 in RAPD markers, and (GA)8T, (GA)9T, and (GTGC)4 in ISSR markers, were found to be the most efficient. Although SSR markers are more advanced, the use of multiple markers still has significant importance in DNA fingerprinting studies.
Article
Chemistry, Analytical
Manaswini Dash, Subhashree Singh, Suprava Sahoo, Basudeba Kar
Summary: The volatile constituents of Piper longum L. leaf were characterized for the first time using two-dimensional gas chromatography-time-of-flight mass spectrometry. A total of 104 constituents were identified, including 20 reported for the first time. Oxygenated sesquiterpenes were found to be the major group, with E-nerolidol as the dominant compound.
ANALYTICAL LETTERS
(2023)
Article
Agricultural Engineering
Snehalata Khuntia, Bhaskar Chandra Sahoo, Jyotirmayee Lenka, Basudeba Kar, Suprava Sahoo
Summary: This study aimed to predict the in-silico interactions of C. caesia volatile constituents against the protein responsible for oxidative and microbial stress in order to investigate their potential for industrial and pharmaceutical applications. The in vitro validation of the antioxidant, antibacterial, and antifungal activity of the essential oils (EOs) derived from C. caesia rhizome and leaves confirmed the accuracy of the in-silico predictions. The major constituents in C. caesia EOs were curzerenone, camphor, eucalyptol, epicurzerenone, germacrone, viridifloral, muurola-4,10(14)-dien-1-ol, and globulol, which may be valuable sources for developing antioxidant and antimicrobial drugs.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Plant Sciences
Bhaskar Chandra Sahoo, Manaswini Dash, Debasis Sahoo, Suprava Sahoo, Basudeba Kar
Summary: Betelvine is an important cash crop in India and other Asian countries, but it faces the threat of anthracnose disease caused by Colletotrichum capsici. This study identified and characterized resistant genes in betelvine against anthracnose disease. The study provides valuable information for the development of resistant betelvine lines.
PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY
(2023)
